Project measure / variable:   Brugnara1   gardos_channel

ID, description, units MPD:47407   gardos_channel   RBC calcium-activated potassium channel (KCNN4)   [mmol/L⋅min]  
Data set, strains Brugnara1   inbred   10 strains     sex: both     age: 8wks
Procedure ion transport assessment
Ontology mappings

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  STRAIN COMPARISON PLOT
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Brugnara1 - RBC calcium-activated potassium channel (KCNN4)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means0.0428   mmol/L⋅min 0.0603   mmol/L⋅min
Median of the strain means0.0391   mmol/L⋅min 0.0519   mmol/L⋅min
SD of the strain means± 0.0153 ± 0.0300
Coefficient of variation (CV)0.357 0.497
Min–max range of strain means0.0201   –   0.0702   mmol/L⋅min 0.0184   –   0.100   mmol/L⋅min
Mean sample size per strain11.2   mice 10.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0132 0.0132 60.9666 < 0.0001
strain 9 0.0651 0.0072 33.3682 < 0.0001
sex:strain 9 0.0398 0.0044 20.403 < 0.0001
Residuals 196 0.0425 0.0002


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.0201 0.00621   10 0.00196 0.309 0.011, 0.033 -1.49
129S1/SvImJ m 0.0184 0.00642   11 0.00194 0.35 0.008, 0.03 -1.4
A/J f 0.0577 0.0195   14 0.0052 0.337 0.03, 0.097 0.97
A/J m 0.0397 0.0139   12 0.00401 0.35 0.022, 0.066 -0.69
BALB/cJ f 0.0553 0.0171   11 0.00515 0.309 0.032, 0.079 0.82
BALB/cJ m 0.1 0.0347   11 0.0105 0.345 0.041, 0.156 1.32
C3H/HeJ f 0.0413 0.0153   13 0.00424 0.371 0.024, 0.07 -0.1
C3H/HeJ m 0.0337 0.00883   10 0.00279 0.262 0.022, 0.049 -0.89
C57BL/6J f 0.0369 0.0118   16 0.00295 0.32 0.019, 0.054 -0.39
C57BL/6J m 0.036 0.0115   10 0.00365 0.32 0.021, 0.065 -0.81
C57BLKS/J f 0.0702 0.0163   10 0.00515 0.232 0.051, 0.106 1.79
C57BLKS/J m 0.0602 0.0112   12 0.00324 0.187 0.042, 0.087 0.0
CBA/J f 0.0501 0.0154   12 0.00445 0.307 0.029, 0.078 0.48
CBA/J m 0.0879 0.00991   9 0.0033 0.113 0.076, 0.103 0.92
DBA/2J f 0.0327 0.0127   10 0.00403 0.39 0.018, 0.054 -0.66
DBA/2J m 0.0926 0.00974   8 0.00344 0.105 0.078, 0.104 1.07
NZW/LacJ f 0.0359 0.012   7 0.00452 0.334 0.023, 0.058 -0.45
NZW/LacJ m 0.0914 0.0149   10 0.00473 0.164 0.068, 0.12 1.03
SM/J f 0.028 0.00411   10 0.0013 0.147 0.021, 0.034 -0.97
SM/J m 0.0436 0.00828   10 0.00262 0.19 0.031, 0.053 -0.56


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.0201 0.0047 0.0293 0.0109
129S1/SvImJ m 0.0184 0.0044 0.0271 0.0096
A/J f 0.0577 0.0039 0.0655 0.05
A/J m 0.0397 0.0043 0.048 0.0313
BALB/cJ f 0.0553 0.0044 0.064 0.0465
BALB/cJ m 0.1005 0.0044 0.1092 0.0917
C3H/HeJ f 0.0413 0.0041 0.0494 0.0333
C3H/HeJ m 0.0337 0.0047 0.0429 0.0245
C57BL/6J f 0.0369 0.0037 0.0441 0.0296
C57BL/6J m 0.036 0.0047 0.0452 0.0268
C57BLKS/J f 0.0702 0.0047 0.0794 0.061
C57BLKS/J m 0.0602 0.0043 0.0685 0.0518
CBA/J f 0.0501 0.0043 0.0585 0.0417
CBA/J m 0.0879 0.0049 0.0976 0.0782
DBA/2J f 0.0327 0.0047 0.0419 0.0235
DBA/2J m 0.0926 0.0052 0.1029 0.0824
NZW/LacJ f 0.0359 0.0056 0.0468 0.0249
NZW/LacJ m 0.0914 0.0047 0.1006 0.0822
SM/J f 0.028 0.0047 0.0372 0.0188
SM/J m 0.0436 0.0047 0.0528 0.0344


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.0192 0.0032 0.0256 0.0129
A/J both 0.0487 0.0029 0.0544 0.043
BALB/cJ both 0.0779 0.0031 0.0841 0.0717
C3H/HeJ both 0.0375 0.0031 0.0436 0.0314
C57BL/6J both 0.0364 0.003 0.0423 0.0306
C57BLKS/J both 0.0652 0.0032 0.0714 0.059
CBA/J both 0.069 0.0032 0.0754 0.0626
DBA/2J both 0.0627 0.0035 0.0695 0.0558
NZW/LacJ both 0.0636 0.0036 0.0708 0.0565
SM/J both 0.0358 0.0033 0.0423 0.0293




  GWAS USING LINEAR MIXED MODELS