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Examples
Phenotype measures associated with
ontology
term
MP:0000950 'abnormal seizure response to pharmacological agent'
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MGI
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This MP term has been mapped to these MPD phenotype measurements to help users find relevant data. It should be noted that MPD measurements typically have a mixture of high-end, low-end and "normal" readings.
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Data set
Procedure / Protocol
Treatment
Phenotype Measure / Variable (click to view)
Panel
No. of Strains
Sex
Age
Sample Size (Avg)
Year
Frankel1:10
Frankel1
electroconvulsion test
lamotrigine
median effective dose (ED
50
) against minimal clonic seizures (CC
97
), transcorneal stimulation (at BH) [mg/kg]
L_MC_BH_TC
5610
inbred
3
m
6-11wks
N=63
2000
Frankel1:12
Frankel1
electroconvulsion test
lamotrigine
median effective dose (ED
50
) against minimal clonic seizures (CC
97
), transcorneal stimulation (at SL) [mg/kg]
L_MC_SL_TC
5612
inbred
3
m
6-11wks
N=51
2000
Frankel1:13
Frankel1
electroconvulsion test
lamotrigine
median effective dose (ED
50
) against maximal tonic hindlimb extension seizure (CC
97
), transcorneal stimulation (at BH) [mg/kg]
L_MT_BH_TC
5613
inbred
3
m
6-11wks
N=52
2000
Frankel1:14
Frankel1
electroconvulsion test
lamotrigine
median effective dose (ED
50
) against maximal tonic hindlimb extension seizure (CC
97
), transcorneal stimulation (at SL) [mg/kg]
L_MT_SL_TC
5614
inbred
3
m
6-11wks
N=45
2000
Schauwecker1:1
Schauwecker1
health assessment
pilocarpine
pilocarpine dose required to induce status epilepticus, mg/kg body weight [mg/kg]
ED100
47701
inbred
8
m
8-10wks
N=4
2012
Schauwecker1:2
Schauwecker1
health assessment
pilocarpine
latency to onset of stage 4 status epilepticus seizures [min]
latency
47702
inbred
8
m
8-10wks
N=4
2012
Schauwecker1:3
Schauwecker1
health assessment
pilocarpine
duration of stage 4 status epilepticus seizures [min]
duration
47703
inbred
8
m
8-10wks
N=4
2012
Schauwecker1:4
Schauwecker1
health assessment
pilocarpine
status epilepticus seizure mortality (0=died; 1=survived) [designation]
survival
47704
inbred
11
m
8-10wks
N=18
2012
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