Phenotype measure:   Frankel1   L_MT_BH_TC

ID, description, units MPD:5613   L_MT_BH_TC   median effective dose (ED50) against maximal tonic hindlimb extension seizure (CC97), transcorneal stimulation (at BH)   [mg/kg]
lamotrigine study
Data set, strains Frankel1   inbred   3 strains     sex: m     age: 6-11wks
Procedure electroconvulsion test
Availability note:Individual animal data were not submitted. Some functionality not available.
Ontology mappings


  STRAIN COMPARISON PLOT
Dimensions Width:   px    Height:   px
Download Plot   
Visualization Options

Frankel1 - median effective dose (ED50) against maximal tonic hindlimb extension seizure (CC97), transcorneal stimulation (at BH)



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested3 strains
Mean of the strain means3.08   mg/kg
Median of the strain means3.01   mg/kg
SD of the strain means± 1.55
Coefficient of variation (CV)0.503
Min–max range of strain means1.57   –   4.67   mg/kg
Mean sample size per strain52.3   mice


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BALB/cByJ m 4.67 None   64 None None None, None 1.02
C3HeB/FeJ m 3.01 None   43 None None None, None -0.05
C57BL/6J m 1.57 None   50 None None None, None -0.98