Project measure / variable:   Berndt2   airway_res_mch3

ID, description, units MPD:35183   airway_res_mch3   airway resistance (H20 pressure)   [cm/mL/s]  3 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure ventilator
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  STRAIN COMPARISON PLOT
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Berndt2 - airway resistance (H20 pressure) 3 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.677   cm/mL/s 0.767   cm/mL/s
Median of the strain means0.698   cm/mL/s 0.707   cm/mL/s
SD of the strain means± 0.205 ± 0.203
Coefficient of variation (CV)0.303 0.265
Min–max range of strain means0.374   –   1.11   cm/mL/s 0.412   –   1.22   cm/mL/s
Mean sample size per strain8.7   mice 9.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.8844 0.8844 19.3937 < 0.0001
strain 28 16.6526 0.5947 13.0415 < 0.0001
sex:strain 28 4.2035 0.1501 3.292 < 0.0001
Residuals 462 21.0688 0.0456


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.379 0.0787   9 0.0262 0.208 0.29, 0.52 -1.45
129S1/SvImJ m 0.48 0.184   8 0.0649 0.383 0.36, 0.92 -1.42
A/J f 0.97 0.284   10 0.0897 0.292 0.61, 1.53 1.43
A/J m 1.22 0.311   9 0.104 0.254 0.64, 1.59 2.23
AKR/J f 0.702 0.172   9 0.0574 0.245 0.38, 0.98 0.12
AKR/J m 1.09 0.308   8 0.109 0.282 0.55, 1.4 1.59
BALB/cByJ f 0.63 0.146   8 0.0515 0.231 0.47, 0.94 -0.23
BALB/cByJ m 0.858 0.389   8 0.138 0.454 0.52, 1.66 0.45
BALB/cJ f 0.674 0.136   8 0.0481 0.202 0.5, 0.9 -0.01
BALB/cJ m 0.881 0.229   10 0.0724 0.26 0.66, 1.43 0.56
BTBR T+ Itpr3tf/J f 0.68 0.213   10 0.0675 0.314 0.33, 1.01 0.02
BTBR T+ Itpr3tf/J m 0.77 0.135   10 0.0428 0.176 0.59, 1.01 0.01
BUB/BnJ f 0.91 0.255   9 0.0849 0.28 0.61, 1.4 1.14
BUB/BnJ m 0.677 0.118   10 0.0374 0.175 0.48, 0.87 -0.45
C3H/HeJ f 0.772 0.218   10 0.0689 0.282 0.47, 1.17 0.46
C3H/HeJ m 0.77 0.158   9 0.0528 0.206 0.62, 1.08 0.01
C57BL/10J f 0.428 0.092   9 0.0307 0.215 0.34, 0.64 -1.21
C57BL/10J m 0.643 0.0815   10 0.0258 0.127 0.54, 0.78 -0.61
C57BL/6J f 0.43 0.148   8 0.0522 0.344 0.26, 0.65 -1.2
C57BL/6J m 0.777 0.23   8 0.0814 0.296 0.44, 1.05 0.05
C57BLKS/J f 0.387 0.114   9 0.0382 0.296 0.27, 0.66 -1.41
C57BLKS/J m 0.672 0.227   12 0.0655 0.338 0.39, 1.04 -0.47
C57BR/cdJ f 0.679 0.19   7 0.0718 0.28 0.38, 0.92 0.01
C57BR/cdJ m 0.743 0.222   10 0.07 0.298 0.53, 1.3 -0.12
C57L/J f 0.708 0.239   6 0.0978 0.338 0.42, 1.0 0.15
C57L/J m 0.629 0.141   10 0.0446 0.224 0.41, 0.83 -0.68
CBA/J f 0.865 0.249   8 0.0881 0.288 0.59, 1.29 0.92
CBA/J m 0.653 0.0914   10 0.0289 0.14 0.47, 0.76 -0.56
CE/J f 0.744 0.309   9 0.103 0.415 0.43, 1.47 0.33
CE/J m 0.738 0.144   9 0.0481 0.196 0.53, 0.94 -0.14
DBA/1J f 0.698 0.232   9 0.0775 0.333 0.44, 1.2 0.1
DBA/1J m 0.707 0.233   10 0.0737 0.33 0.37, 1.14 -0.3
DBA/2J f 0.534 0.0919   10 0.0291 0.172 0.37, 0.65 -0.7
DBA/2J m 0.781 0.144   10 0.0454 0.184 0.57, 1.1 0.07
FVB/NJ f 0.817 0.305   10 0.0963 0.373 0.4, 1.49 0.68
FVB/NJ m 0.611 0.317   10 0.1 0.52 0.21, 1.17 -0.77
I/LnJ f 1.11 0.265   9 0.0885 0.239 0.56, 1.45 2.11
I/LnJ m 1.07 0.368   8 0.13 0.343 0.55, 1.6 1.49
KK/HlJ f 1.04 0.305   9 0.102 0.293 0.48, 1.42 1.77
KK/HlJ m 1.09 0.263   10 0.0833 0.241 0.64, 1.56 1.59
LP/J f 0.374 0.06   9 0.02 0.16 0.31, 0.5 -1.48
LP/J m 0.612 0.0757   10 0.0239 0.124 0.5, 0.74 -0.77
NOD/ShiLtJ f 0.656 0.271   9 0.0902 0.413 0.31, 1.25 -0.1
NOD/ShiLtJ m 0.956 0.363   9 0.121 0.38 0.68, 1.85 0.93
NON/ShiLtJ f 0.866 0.281   7 0.106 0.324 0.62, 1.47 0.92
NON/ShiLtJ m 0.703 0.162   7 0.0611 0.23 0.54, 0.93 -0.32
NZW/LacJ f 0.427 0.0936   8 0.0331 0.219 0.27, 0.53 -1.22
NZW/LacJ m 0.412 0.0432   10 0.0136 0.105 0.36, 0.49 -1.75
PL/J f 0.752 0.182   9 0.0607 0.242 0.53, 1.09 0.37
PL/J m 1.17 0.138   8 0.0486 0.118 1.04, 1.47 1.98
RIIIS/J f 0.79 0.356   6 0.145 0.451 0.39, 1.31 0.55
RIIIS/J m 0.688 0.202   9 0.0674 0.294 0.4, 1.11 -0.39
SJL/J f 0.47 0.0974   8 0.0344 0.207 0.37, 0.65 -1.01
SJL/J m 0.659 0.15   9 0.05 0.227 0.48, 0.89 -0.53
SM/J f 0.733 0.269   10 0.085 0.367 0.48, 1.28 0.27
SM/J m 0.703 0.144   8 0.0511 0.206 0.55, 0.96 -0.32
SWR/J f 0.404 0.0835   9 0.0278 0.207 0.28, 0.52 -1.33
SWR/J m 0.491 0.13   10 0.0411 0.265 0.38, 0.79 -1.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.3789 0.0712 0.5188 0.239
129S1/SvImJ m 0.48 0.0755 0.6284 0.3316
A/J f 0.97 0.0675 1.1027 0.8373
A/J m 1.2244 0.0712 1.3643 1.0846
AKR/J f 0.7022 0.0712 0.8421 0.5623
AKR/J m 1.095 0.0755 1.2434 0.9466
BALB/cByJ f 0.63 0.0755 0.7784 0.4816
BALB/cByJ m 0.8575 0.0755 1.0059 0.7091
BALB/cJ f 0.6737 0.0755 0.8221 0.5254
BALB/cJ m 0.881 0.0675 1.0137 0.7483
BTBR T+ Itpr3tf/J f 0.68 0.0675 0.8127 0.5473
BTBR T+ Itpr3tf/J m 0.77 0.0675 0.9027 0.6373
BUB/BnJ f 0.91 0.0712 1.0499 0.7701
BUB/BnJ m 0.677 0.0675 0.8097 0.5443
C3H/HeJ f 0.772 0.0675 0.9047 0.6393
C3H/HeJ m 0.77 0.0712 0.9099 0.6301
C57BL/10J f 0.4278 0.0712 0.5677 0.2879
C57BL/10J m 0.643 0.0675 0.7757 0.5103
C57BL/6J f 0.43 0.0755 0.5784 0.2816
C57BL/6J m 0.7775 0.0755 0.9259 0.6291
C57BLKS/J f 0.3867 0.0712 0.5265 0.2468
C57BLKS/J m 0.6717 0.0616 0.7928 0.5505
C57BR/cdJ f 0.6786 0.0807 0.8372 0.52
C57BR/cdJ m 0.743 0.0675 0.8757 0.6103
C57L/J f 0.7083 0.0872 0.8797 0.537
C57L/J m 0.629 0.0675 0.7617 0.4963
CBA/J f 0.865 0.0755 1.0134 0.7166
CBA/J m 0.653 0.0675 0.7857 0.5203
CE/J f 0.7444 0.0712 0.8843 0.6046
CE/J m 0.7378 0.0712 0.8777 0.5979
DBA/1J f 0.6978 0.0712 0.8377 0.5579
DBA/1J m 0.707 0.0675 0.8397 0.5743
DBA/2J f 0.534 0.0675 0.6667 0.4013
DBA/2J m 0.781 0.0675 0.9137 0.6483
FVB/NJ f 0.817 0.0675 0.9497 0.6843
FVB/NJ m 0.611 0.0675 0.7437 0.4783
I/LnJ f 1.11 0.0712 1.2499 0.9701
I/LnJ m 1.0725 0.0755 1.2209 0.9241
KK/HlJ f 1.0422 0.0712 1.1821 0.9023
KK/HlJ m 1.092 0.0675 1.2247 0.9593
LP/J f 0.3744 0.0712 0.5143 0.2346
LP/J m 0.612 0.0675 0.7447 0.4793
NOD/ShiLtJ f 0.6556 0.0712 0.7954 0.5157
NOD/ShiLtJ m 0.9556 0.0712 1.0954 0.8157
NON/ShiLtJ f 0.8657 0.0807 1.0243 0.7071
NON/ShiLtJ m 0.7029 0.0807 0.8615 0.5442
NZW/LacJ f 0.4275 0.0755 0.5759 0.2791
NZW/LacJ m 0.412 0.0675 0.5447 0.2793
PL/J f 0.7522 0.0712 0.8921 0.6123
PL/J m 1.165 0.0755 1.3134 1.0166
RIIIS/J f 0.79 0.0872 0.9613 0.6187
RIIIS/J m 0.6878 0.0712 0.8277 0.5479
SJL/J f 0.47 0.0755 0.6184 0.3216
SJL/J m 0.6589 0.0712 0.7988 0.519
SM/J f 0.733 0.0675 0.8657 0.6003
SM/J m 0.7025 0.0755 0.8509 0.5541
SWR/J f 0.4044 0.0712 0.5443 0.2646
SWR/J m 0.491 0.0675 0.6237 0.3583


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.4294 0.0519 0.5314 0.3275
A/J both 1.0972 0.0491 1.1936 1.0008
AKR/J both 0.8986 0.0519 1.0006 0.7967
BALB/cByJ both 0.7438 0.0534 0.8487 0.6388
BALB/cJ both 0.7774 0.0506 0.8769 0.6778
BTBR T+ Itpr3tf/J both 0.725 0.0478 0.8188 0.6312
BUB/BnJ both 0.7935 0.0491 0.8899 0.6971
C3H/HeJ both 0.771 0.0491 0.8674 0.6746
C57BL/10J both 0.5354 0.0491 0.6318 0.439
C57BL/6J both 0.6038 0.0534 0.7087 0.4988
C57BLKS/J both 0.5292 0.0471 0.6217 0.4366
C57BR/cdJ both 0.7108 0.0526 0.8142 0.6074
C57L/J both 0.6687 0.0551 0.777 0.5603
CBA/J both 0.759 0.0506 0.8585 0.6595
CE/J both 0.7411 0.0503 0.84 0.6422
DBA/1J both 0.7024 0.0491 0.7988 0.606
DBA/2J both 0.6575 0.0478 0.7513 0.5637
FVB/NJ both 0.714 0.0478 0.8078 0.6202
I/LnJ both 1.0912 0.0519 1.1932 0.9893
KK/HlJ both 1.0671 0.0491 1.1635 0.9707
LP/J both 0.4932 0.0491 0.5896 0.3968
NOD/ShiLtJ both 0.8056 0.0503 0.9045 0.7066
NON/ShiLtJ both 0.7843 0.0571 0.8964 0.6721
NZW/LacJ both 0.4198 0.0506 0.5193 0.3202
PL/J both 0.9586 0.0519 1.0606 0.8567
RIIIS/J both 0.7389 0.0563 0.8495 0.6283
SJL/J both 0.5644 0.0519 0.6664 0.4625
SM/J both 0.7178 0.0506 0.8173 0.6182
SWR/J both 0.4477 0.0491 0.5441 0.3513




  GWAS USING LINEAR MIXED MODELS