Project measure / variable:   Berndt2   resp_flow_mch10

ID, description, units MPD:35156   resp_flow_mch10   respiratory flow rate   [mL/kg/s]  10 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - respiratory flow rate 10 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.869   mL/kg/s 1.04   mL/kg/s
Median of the strain means0.869   mL/kg/s 0.984   mL/kg/s
SD of the strain means± 0.319 ± 0.361
Coefficient of variation (CV)0.367 0.348
Min–max range of strain means0.390   –   1.85   mL/kg/s 0.506   –   2.05   mL/kg/s
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.8691 2.8691 43.1579 < 0.0001
strain 28 50.7282 1.8117 27.2525 < 0.0001
sex:strain 28 3.0622 0.1094 1.6451 0.022
Residuals 412 27.3894 0.0665


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.641 0.272   8 0.0961 0.424 0.376, 1.17 -0.71
129S1/SvImJ m 0.871 0.305   8 0.108 0.351 0.448, 1.2 -0.46
A/J f 0.959 0.22   8 0.0777 0.229 0.706, 1.23 0.28
A/J m 0.944 0.151   8 0.0533 0.16 0.719, 1.16 -0.26
AKR/J f 1.06 0.441   8 0.156 0.415 0.579, 1.91 0.6
AKR/J m 1.13 0.292   8 0.103 0.259 0.673, 1.52 0.26
BALB/cByJ f 1.21 0.235   8 0.083 0.194 0.962, 1.66 1.07
BALB/cByJ m 1.21 0.294   8 0.104 0.243 0.555, 1.53 0.48
BALB/cJ f 1.56 0.498   10 0.158 0.32 0.842, 2.45 2.16
BALB/cJ m 1.74 0.316   10 0.1 0.182 1.15, 2.18 1.95
BTBR T+ Itpr3tf/J f 1.85 0.278   8 0.0984 0.15 1.51, 2.19 3.07
BTBR T+ Itpr3tf/J m 2.05 0.312   8 0.11 0.153 1.36, 2.42 2.81
BUB/BnJ f 0.869 0.201   7 0.076 0.231 0.584, 1.11 0.0
BUB/BnJ m 1.13 0.255   8 0.09 0.224 0.849, 1.52 0.26
C3H/HeJ f 0.634 0.124   8 0.0437 0.195 0.404, 0.775 -0.74
C3H/HeJ m 0.693 0.275   8 0.0973 0.397 0.313, 1.26 -0.96
C57BL/10J f 0.999 0.146   8 0.0517 0.146 0.808, 1.28 0.41
C57BL/10J m 1.56 0.265   7 0.1 0.169 1.24, 2.07 1.45
C57BL/6J f 0.769 0.133   7 0.0502 0.173 0.575, 0.907 -0.31
C57BL/6J m 0.897 0.304   13 0.0842 0.338 0.505, 1.5 -0.39
C57BLKS/J f 0.968 0.195   11 0.0588 0.202 0.729, 1.35 0.31
C57BLKS/J m 1.28 0.575   8 0.203 0.45 0.485, 1.85 0.67
C57BR/cdJ f 0.89 0.323   6 0.132 0.362 0.589, 1.37 0.07
C57BR/cdJ m 1.18 0.328   8 0.116 0.279 0.798, 1.82 0.39
C57L/J f 0.849 0.198   8 0.0702 0.234 0.593, 1.11 -0.06
C57L/J m 1.32 0.329   8 0.116 0.249 0.805, 1.84 0.78
CBA/J f 0.943 0.105   8 0.037 0.111 0.81, 1.06 0.23
CBA/J m 0.984 0.189   8 0.0668 0.192 0.756, 1.31 -0.15
CE/J f 0.636 0.185   8 0.0653 0.29 0.363, 0.872 -0.73
CE/J m 0.872 0.267   9 0.089 0.306 0.552, 1.38 -0.46
DBA/1J f 0.932 0.241   10 0.0761 0.258 0.552, 1.36 0.2
DBA/1J m 1.08 0.209   8 0.0741 0.195 0.678, 1.32 0.12
DBA/2J f 0.869 0.157   8 0.0554 0.18 0.6, 1.04 0.0
DBA/2J m 0.776 0.138   10 0.0436 0.178 0.561, 1.04 -0.73
FVB/NJ f 0.717 0.114   8 0.0403 0.159 0.56, 0.858 -0.48
FVB/NJ m 1.34 0.341   7 0.129 0.255 0.847, 1.88 0.84
I/LnJ f 0.756 0.237   7 0.0897 0.314 0.399, 0.976 -0.35
I/LnJ m 0.941 0.324   5 0.145 0.344 0.652, 1.49 -0.27
KK/HlJ f 1.02 0.226   8 0.08 0.222 0.786, 1.51 0.47
KK/HlJ m 1.12 0.359   6 0.147 0.319 0.59, 1.66 0.23
LP/J f 0.463 0.133   8 0.0471 0.288 0.321, 0.668 -1.27
LP/J m 0.568 0.242   8 0.0854 0.426 0.418, 1.15 -1.3
NOD/ShiLtJ f 0.877 0.222   8 0.0785 0.253 0.622, 1.2 0.02
NOD/ShiLtJ m 1.0 0.296   8 0.104 0.295 0.644, 1.37 -0.1
NON/ShiLtJ f 0.39 0.0629   8 0.0222 0.161 0.305, 0.507 -1.5
NON/ShiLtJ m 0.597 0.211   8 0.0746 0.353 0.388, 0.955 -1.22
NZW/LacJ f 0.79 0.151   8 0.0534 0.191 0.51, 1.06 -0.25
NZW/LacJ m 0.824 0.286   8 0.101 0.347 0.545, 1.4 -0.59
PL/J f 0.408 0.127   8 0.0448 0.311 0.253, 0.563 -1.44
PL/J m 0.547 0.101   8 0.0358 0.185 0.447, 0.724 -1.36
RIIIS/J f 0.8 0.134   8 0.0474 0.168 0.664, 1.07 -0.22
RIIIS/J m 0.794 0.135   8 0.0476 0.17 0.618, 0.975 -0.68
SJL/J f 0.538 0.165   8 0.0584 0.307 0.392, 0.866 -1.04
SJL/J m 0.506 0.161   8 0.0569 0.318 0.348, 0.814 -1.47
SM/J f 1.26 0.27   8 0.0954 0.214 0.911, 1.6 1.22
SM/J m 1.4 0.341   8 0.121 0.243 1.02, 1.95 1.0
SWR/J f 0.546 0.162   8 0.0572 0.296 0.363, 0.773 -1.01
SWR/J m 0.743 0.265   9 0.0883 0.356 0.463, 1.27 -0.82


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.6407 0.0912 0.8199 0.4616
129S1/SvImJ m 0.8705 0.0912 1.0497 0.6913
A/J f 0.9586 0.0912 1.1378 0.7794
A/J m 0.9443 0.0912 1.1234 0.7651
AKR/J f 1.0621 0.0912 1.2413 0.8829
AKR/J m 1.1285 0.0912 1.3077 0.9493
BALB/cByJ f 1.2078 0.0912 1.3869 1.0286
BALB/cByJ m 1.2069 0.0912 1.3861 1.0277
BALB/cJ f 1.5582 0.0815 1.7185 1.3979
BALB/cJ m 1.737 0.0815 1.8973 1.5767
BTBR T+ Itpr3tf/J f 1.8512 0.0912 2.0304 1.6721
BTBR T+ Itpr3tf/J m 2.0475 0.0912 2.2267 1.8683
BUB/BnJ f 0.8689 0.0975 1.0604 0.6773
BUB/BnJ m 1.1346 0.0912 1.3138 0.9554
C3H/HeJ f 0.6344 0.0912 0.8136 0.4552
C3H/HeJ m 0.693 0.0912 0.8722 0.5138
C57BL/10J f 0.999 0.0912 1.1782 0.8198
C57BL/10J m 1.5643 0.0975 1.7559 1.3727
C57BL/6J f 0.7686 0.0975 0.9601 0.577
C57BL/6J m 0.8974 0.0715 1.038 0.7568
C57BLKS/J f 0.9675 0.0777 1.1204 0.8147
C57BLKS/J m 1.2779 0.0912 1.4571 1.0987
C57BR/cdJ f 0.8905 0.1053 1.0974 0.6836
C57BR/cdJ m 1.1778 0.0912 1.3569 0.9986
C57L/J f 0.8489 0.0912 1.0281 0.6697
C57L/J m 1.3231 0.0912 1.5023 1.1439
CBA/J f 0.9426 0.0912 1.1218 0.7634
CBA/J m 0.9844 0.0912 1.1636 0.8052
CE/J f 0.6362 0.0912 0.8154 0.4571
CE/J m 0.8722 0.0859 1.0412 0.7033
DBA/1J f 0.9323 0.0815 1.0926 0.772
DBA/1J m 1.0759 0.0912 1.2551 0.8967
DBA/2J f 0.869 0.0912 1.0482 0.6898
DBA/2J m 0.7764 0.0815 0.9367 0.6161
FVB/NJ f 0.7166 0.0912 0.8958 0.5374
FVB/NJ m 1.3367 0.0975 1.5283 1.1451
I/LnJ f 0.7556 0.0975 0.9471 0.564
I/LnJ m 0.9406 0.1153 1.1673 0.7139
KK/HlJ f 1.0186 0.0912 1.1978 0.8394
KK/HlJ m 1.125 0.1053 1.3319 0.9181
LP/J f 0.4629 0.0912 0.6421 0.2837
LP/J m 0.5677 0.0912 0.7469 0.3886
NOD/ShiLtJ f 0.8765 0.0912 1.0557 0.6973
NOD/ShiLtJ m 1.0008 0.0912 1.1799 0.8216
NON/ShiLtJ f 0.3899 0.0912 0.5691 0.2107
NON/ShiLtJ m 0.597 0.0912 0.7762 0.4178
NZW/LacJ f 0.7897 0.0912 0.9689 0.6106
NZW/LacJ m 0.8242 0.0912 1.0034 0.6451
PL/J f 0.4084 0.0912 0.5876 0.2292
PL/J m 0.5471 0.0912 0.7263 0.3679
RIIIS/J f 0.8003 0.0912 0.9794 0.6211
RIIIS/J m 0.7938 0.0912 0.9729 0.6146
SJL/J f 0.5382 0.0912 0.7174 0.3591
SJL/J m 0.5059 0.0912 0.6851 0.3267
SM/J f 1.2614 0.0912 1.4406 1.0822
SM/J m 1.405 0.0912 1.5842 1.2258
SWR/J f 0.5459 0.0912 0.7251 0.3667
SWR/J m 0.7434 0.0859 0.9124 0.5745


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.7556 0.0645 0.8823 0.6289
A/J both 0.9514 0.0645 1.0781 0.8247
AKR/J both 1.0953 0.0645 1.222 0.9686
BALB/cByJ both 1.2073 0.0645 1.334 1.0806
BALB/cJ both 1.6476 0.0577 1.7609 1.5343
BTBR T+ Itpr3tf/J both 1.9494 0.0645 2.0761 1.8227
BUB/BnJ both 1.0017 0.0667 1.1329 0.8706
C3H/HeJ both 0.6637 0.0645 0.7904 0.537
C57BL/10J both 1.2816 0.0667 1.4128 1.1505
C57BL/6J both 0.833 0.0604 0.9518 0.7142
C57BLKS/J both 1.1227 0.0599 1.2405 1.005
C57BR/cdJ both 1.0341 0.0696 1.171 0.8973
C57L/J both 1.086 0.0645 1.2127 0.9593
CBA/J both 0.9635 0.0645 1.0902 0.8368
CE/J both 0.7542 0.0626 0.8774 0.6311
DBA/1J both 1.0041 0.0612 1.1243 0.8839
DBA/2J both 0.8227 0.0612 0.9429 0.7025
FVB/NJ both 1.0267 0.0667 1.1578 0.8955
I/LnJ both 0.8481 0.0755 0.9965 0.6997
KK/HlJ both 1.0718 0.0696 1.2087 0.935
LP/J both 0.5153 0.0645 0.642 0.3886
NOD/ShiLtJ both 0.9386 0.0645 1.0653 0.8119
NON/ShiLtJ both 0.4934 0.0645 0.6201 0.3667
NZW/LacJ both 0.807 0.0645 0.9337 0.6803
PL/J both 0.4778 0.0645 0.6045 0.351
RIIIS/J both 0.797 0.0645 0.9237 0.6703
SJL/J both 0.5221 0.0645 0.6488 0.3954
SM/J both 1.3332 0.0645 1.4599 1.2065
SWR/J both 0.6447 0.0626 0.7678 0.5215




  GWAS USING LINEAR MIXED MODELS