Project measure / variable:   Berndt2   resp_flow_mch5

ID, description, units MPD:35155   resp_flow_mch5   respiratory flow rate   [mL/kg/s]  5 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - respiratory flow rate 5 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.824   mL/kg/s 0.908   mL/kg/s
Median of the strain means0.779   mL/kg/s 0.832   mL/kg/s
SD of the strain means± 0.209 ± 0.300
Coefficient of variation (CV)0.254 0.330
Min–max range of strain means0.527   –   1.35   mL/kg/s 0.584   –   2.13   mL/kg/s
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.8173 0.8173 12.7148 0.0004
strain 28 26.9333 0.9619 14.9639 < 0.0001
sex:strain 28 3.9189 0.14 2.1773 0.0006
Residuals 412 26.4839 0.0643


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.575 0.163   8 0.0577 0.284 0.389, 0.84 -1.19
129S1/SvImJ m 0.662 0.297   8 0.105 0.449 0.375, 1.15 -0.82
A/J f 0.945 0.158   8 0.0557 0.167 0.756, 1.18 0.58
A/J m 0.934 0.166   8 0.0587 0.178 0.727, 1.23 0.09
AKR/J f 0.977 0.355   8 0.125 0.363 0.583, 1.74 0.73
AKR/J m 0.764 0.175   8 0.0619 0.229 0.584, 1.11 -0.48
BALB/cByJ f 1.04 0.191   8 0.0676 0.183 0.736, 1.3 1.03
BALB/cByJ m 1.18 0.234   8 0.0826 0.198 0.796, 1.51 0.91
BALB/cJ f 1.35 0.26   10 0.0821 0.193 0.92, 1.72 2.51
BALB/cJ m 1.43 0.308   10 0.0975 0.215 1.11, 2.12 1.74
BTBR T+ Itpr3tf/J f 1.31 0.484   8 0.171 0.369 0.711, 2.29 2.32
BTBR T+ Itpr3tf/J m 2.13 0.321   8 0.113 0.15 1.75, 2.68 4.08
BUB/BnJ f 0.923 0.269   7 0.102 0.291 0.544, 1.34 0.47
BUB/BnJ m 0.755 0.28   8 0.099 0.371 0.47, 1.32 -0.51
C3H/HeJ f 0.668 0.177   8 0.0625 0.265 0.356, 0.925 -0.75
C3H/HeJ m 0.777 0.289   8 0.102 0.372 0.449, 1.38 -0.44
C57BL/10J f 0.976 0.175   8 0.0618 0.179 0.691, 1.28 0.72
C57BL/10J m 1.07 0.251   7 0.0948 0.234 0.768, 1.52 0.54
C57BL/6J f 0.779 0.103   7 0.039 0.132 0.632, 0.935 -0.22
C57BL/6J m 0.823 0.253   13 0.07 0.307 0.422, 1.38 -0.28
C57BLKS/J f 0.821 0.208   11 0.0627 0.253 0.425, 1.04 -0.02
C57BLKS/J m 0.853 0.235   8 0.0832 0.276 0.487, 1.12 -0.18
C57BR/cdJ f 1.18 0.683   6 0.279 0.581 0.685, 2.53 1.7
C57BR/cdJ m 0.992 0.388   8 0.137 0.391 0.619, 1.7 0.28
C57L/J f 0.836 0.123   8 0.0436 0.148 0.644, 0.969 0.06
C57L/J m 0.972 0.161   8 0.057 0.166 0.739, 1.28 0.21
CBA/J f 0.777 0.0513   8 0.0181 0.066 0.684, 0.853 -0.23
CBA/J m 0.838 0.131   8 0.0462 0.156 0.643, 0.989 -0.23
CE/J f 0.732 0.19   8 0.0672 0.26 0.361, 1.04 -0.44
CE/J m 0.832 0.202   9 0.0675 0.243 0.393, 1.09 -0.25
DBA/1J f 0.717 0.21   10 0.0664 0.293 0.355, 1.02 -0.51
DBA/1J m 0.919 0.17   8 0.0601 0.185 0.671, 1.17 0.04
DBA/2J f 0.806 0.154   8 0.0545 0.191 0.539, 0.992 -0.09
DBA/2J m 0.793 0.149   10 0.047 0.188 0.556, 0.99 -0.38
FVB/NJ f 0.77 0.319   8 0.113 0.415 0.47, 1.28 -0.26
FVB/NJ m 1.16 0.558   7 0.211 0.483 0.653, 2.17 0.84
I/LnJ f 0.747 0.217   7 0.0818 0.29 0.44, 1.07 -0.37
I/LnJ m 0.888 0.126   5 0.0562 0.142 0.695, 1.01 -0.07
KK/HlJ f 0.822 0.114   8 0.0403 0.139 0.612, 0.941 -0.01
KK/HlJ m 0.743 0.201   6 0.082 0.27 0.506, 1.03 -0.55
LP/J f 0.527 0.236   8 0.0834 0.448 0.237, 0.903 -1.42
LP/J m 0.653 0.266   8 0.0939 0.407 0.269, 1.09 -0.85
NOD/ShiLtJ f 0.64 0.248   8 0.0878 0.388 0.455, 1.23 -0.88
NOD/ShiLtJ m 0.865 0.477   8 0.169 0.552 0.531, 1.89 -0.14
NON/ShiLtJ f 0.693 0.22   8 0.0778 0.318 0.42, 1.15 -0.63
NON/ShiLtJ m 0.83 0.228   8 0.0806 0.274 0.599, 1.12 -0.26
NZW/LacJ f 0.867 0.169   8 0.0596 0.195 0.604, 1.02 0.2
NZW/LacJ m 0.777 0.143   8 0.0506 0.184 0.565, 1.01 -0.44
PL/J f 0.599 0.117   8 0.0412 0.195 0.474, 0.824 -1.08
PL/J m 0.619 0.172   8 0.0608 0.278 0.421, 0.88 -0.97
RIIIS/J f 0.712 0.1   8 0.0354 0.141 0.606, 0.833 -0.54
RIIIS/J m 0.803 0.0951   8 0.0336 0.118 0.648, 0.949 -0.35
SJL/J f 0.59 0.232   8 0.0819 0.393 0.321, 0.923 -1.12
SJL/J m 0.584 0.216   8 0.0763 0.369 0.38, 0.938 -1.08
SM/J f 0.969 0.261   8 0.0923 0.269 0.638, 1.38 0.69
SM/J m 1.06 0.43   8 0.152 0.407 0.662, 1.99 0.51
SWR/J f 0.559 0.146   8 0.0516 0.261 0.356, 0.746 -1.27
SWR/J m 0.634 0.134   9 0.0446 0.211 0.482, 0.917 -0.92


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.5752 0.0896 0.7515 0.399
129S1/SvImJ m 0.6621 0.0896 0.8383 0.4859
A/J f 0.9447 0.0896 1.121 0.7685
A/J m 0.934 0.0896 1.1102 0.7578
AKR/J f 0.9768 0.0896 1.153 0.8005
AKR/J m 0.764 0.0896 0.9402 0.5878
BALB/cByJ f 1.0449 0.0896 1.2211 0.8687
BALB/cByJ m 1.1774 0.0896 1.3536 1.0012
BALB/cJ f 1.347 0.0802 1.5046 1.1894
BALB/cJ m 1.434 0.0802 1.5916 1.2764
BTBR T+ Itpr3tf/J f 1.3114 0.0896 1.4876 1.1352
BTBR T+ Itpr3tf/J m 2.135 0.0896 2.3112 1.9588
BUB/BnJ f 0.9233 0.0958 1.1117 0.7349
BUB/BnJ m 0.7549 0.0896 0.9311 0.5787
C3H/HeJ f 0.668 0.0896 0.8442 0.4918
C3H/HeJ m 0.7766 0.0896 0.9528 0.6004
C57BL/10J f 0.9764 0.0896 1.1526 0.8002
C57BL/10J m 1.0701 0.0958 1.2585 0.8818
C57BL/6J f 0.7789 0.0958 0.9672 0.5905
C57BL/6J m 0.8228 0.0703 0.961 0.6845
C57BLKS/J f 0.8211 0.0764 0.9714 0.6708
C57BLKS/J m 0.8528 0.0896 1.029 0.6765
C57BR/cdJ f 1.1758 0.1035 1.3793 0.9724
C57BR/cdJ m 0.9924 0.0896 1.1686 0.8162
C57L/J f 0.8356 0.0896 1.0118 0.6594
C57L/J m 0.9724 0.0896 1.1486 0.7962
CBA/J f 0.7774 0.0896 0.9536 0.6012
CBA/J m 0.838 0.0896 1.0142 0.6618
CE/J f 0.7322 0.0896 0.9085 0.556
CE/J m 0.8322 0.0845 0.9984 0.6661
DBA/1J f 0.717 0.0802 0.8746 0.5594
DBA/1J m 0.9188 0.0896 1.095 0.7425
DBA/2J f 0.8064 0.0896 0.9826 0.6302
DBA/2J m 0.7931 0.0802 0.9507 0.6355
FVB/NJ f 0.7695 0.0896 0.9457 0.5933
FVB/NJ m 1.1554 0.0958 1.3438 0.9671
I/LnJ f 0.7467 0.0958 0.9351 0.5583
I/LnJ m 0.8876 0.1134 1.1105 0.6647
KK/HlJ f 0.8225 0.0896 0.9987 0.6463
KK/HlJ m 0.7427 0.1035 0.9461 0.5392
LP/J f 0.5269 0.0896 0.7031 0.3507
LP/J m 0.6528 0.0896 0.829 0.4765
NOD/ShiLtJ f 0.6395 0.0896 0.8157 0.4633
NOD/ShiLtJ m 0.8646 0.0896 1.0408 0.6884
NON/ShiLtJ f 0.6927 0.0896 0.869 0.5165
NON/ShiLtJ m 0.8304 0.0896 1.0066 0.6542
NZW/LacJ f 0.8669 0.0896 1.0431 0.6907
NZW/LacJ m 0.7771 0.0896 0.9533 0.6009
PL/J f 0.5985 0.0896 0.7747 0.4223
PL/J m 0.6191 0.0896 0.7953 0.4429
RIIIS/J f 0.7119 0.0896 0.8881 0.5357
RIIIS/J m 0.8028 0.0896 0.979 0.6265
SJL/J f 0.5897 0.0896 0.766 0.4135
SJL/J m 0.5845 0.0896 0.7607 0.4083
SM/J f 0.9689 0.0896 1.1451 0.7927
SM/J m 1.056 0.0896 1.2322 0.8798
SWR/J f 0.5593 0.0896 0.7355 0.383
SWR/J m 0.6344 0.0845 0.8006 0.4683


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.6187 0.0634 0.7433 0.4941
A/J both 0.9394 0.0634 1.064 0.8148
AKR/J both 0.8704 0.0634 0.995 0.7458
BALB/cByJ both 1.1111 0.0634 1.2357 0.9865
BALB/cJ both 1.3905 0.0567 1.5019 1.2791
BTBR T+ Itpr3tf/J both 1.7232 0.0634 1.8478 1.5986
BUB/BnJ both 0.8391 0.0656 0.9681 0.7101
C3H/HeJ both 0.7223 0.0634 0.8469 0.5977
C57BL/10J both 1.0233 0.0656 1.1522 0.8943
C57BL/6J both 0.8008 0.0594 0.9176 0.684
C57BLKS/J both 0.8369 0.0589 0.9527 0.7211
C57BR/cdJ both 1.0841 0.0685 1.2187 0.9495
C57L/J both 0.904 0.0634 1.0286 0.7794
CBA/J both 0.8077 0.0634 0.9323 0.6831
CE/J both 0.7822 0.0616 0.9033 0.6611
DBA/1J both 0.8179 0.0601 0.9361 0.6997
DBA/2J both 0.7997 0.0601 0.9179 0.6815
FVB/NJ both 0.9625 0.0656 1.0914 0.8335
I/LnJ both 0.8172 0.0742 0.9631 0.6712
KK/HlJ both 0.7826 0.0685 0.9172 0.648
LP/J both 0.5898 0.0634 0.7144 0.4652
NOD/ShiLtJ both 0.7521 0.0634 0.8767 0.6275
NON/ShiLtJ both 0.7616 0.0634 0.8862 0.637
NZW/LacJ both 0.822 0.0634 0.9466 0.6974
PL/J both 0.6088 0.0634 0.7334 0.4842
RIIIS/J both 0.7573 0.0634 0.8819 0.6327
SJL/J both 0.5871 0.0634 0.7117 0.4625
SM/J both 1.0124 0.0634 1.137 0.8878
SWR/J both 0.5968 0.0616 0.7179 0.4758




  GWAS USING LINEAR MIXED MODELS