Project measure / variable:   Berndt2   resp_flow_mch20

ID, description, units MPD:35157   resp_flow_mch20   respiratory flow rate   [mL/kg/s]  20 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - respiratory flow rate 20 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means1.08   mL/kg/s 1.20   mL/kg/s
Median of the strain means1.11   mL/kg/s 1.22   mL/kg/s
SD of the strain means± 0.364 ± 0.379
Coefficient of variation (CV)0.338 0.316
Min–max range of strain means0.436   –   1.84   mL/kg/s 0.591   –   1.72   mL/kg/s
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.0509 2.0509 25.1214 < 0.0001
strain 28 57.3254 2.0473 25.0783 < 0.0001
sex:strain 28 4.9616 0.1772 2.1706 0.0006
Residuals 412 33.6348 0.0816


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.26 0.418   8 0.148 0.332 0.767, 2.04 0.51
129S1/SvImJ m 1.32 0.433   8 0.153 0.329 0.549, 1.85 0.31
A/J f 0.677 0.171   8 0.0603 0.252 0.48, 1.04 -1.09
A/J m 0.669 0.109   8 0.0386 0.163 0.551, 0.872 -1.4
AKR/J f 1.24 0.515   8 0.182 0.414 0.717, 2.41 0.45
AKR/J m 1.62 0.333   8 0.118 0.206 1.04, 1.97 1.1
BALB/cByJ f 1.22 0.348   8 0.123 0.284 0.911, 1.98 0.4
BALB/cByJ m 1.45 0.403   8 0.143 0.278 0.741, 2.0 0.66
BALB/cJ f 1.33 0.211   10 0.0668 0.159 0.958, 1.71 0.7
BALB/cJ m 1.5 0.279   10 0.0882 0.186 0.864, 1.8 0.79
BTBR T+ Itpr3tf/J f 1.4 0.244   8 0.0861 0.174 1.17, 1.93 0.89
BTBR T+ Itpr3tf/J m 1.65 0.299   8 0.106 0.181 1.07, 2.0 1.18
BUB/BnJ f 1.23 0.382   7 0.144 0.312 0.531, 1.77 0.43
BUB/BnJ m 1.01 0.312   8 0.11 0.31 0.604, 1.64 -0.5
C3H/HeJ f 0.786 0.252   8 0.089 0.32 0.473, 1.17 -0.8
C3H/HeJ m 0.891 0.415   8 0.147 0.466 0.308, 1.58 -0.82
C57BL/10J f 1.53 0.277   8 0.0981 0.181 1.09, 1.93 1.25
C57BL/10J m 1.63 0.294   7 0.111 0.18 1.28, 2.11 1.13
C57BL/6J f 1.39 0.323   7 0.122 0.232 1.0, 1.81 0.86
C57BL/6J m 1.71 0.409   13 0.113 0.239 0.766, 2.21 1.34
C57BLKS/J f 1.39 0.411   11 0.124 0.295 0.66, 1.89 0.86
C57BLKS/J m 1.54 0.371   8 0.131 0.242 1.1, 2.24 0.89
C57BR/cdJ f 1.84 0.46   6 0.188 0.25 1.16, 2.53 2.1
C57BR/cdJ m 1.68 0.362   8 0.128 0.216 1.05, 2.15 1.26
C57L/J f 1.41 0.223   8 0.0788 0.158 1.03, 1.63 0.92
C57L/J m 1.64 0.152   8 0.0538 0.0926 1.45, 1.86 1.16
CBA/J f 1.49 0.208   8 0.0734 0.139 1.21, 1.79 1.14
CBA/J m 1.62 0.179   8 0.0632 0.111 1.36, 1.77 1.1
CE/J f 0.89 0.28   8 0.0989 0.314 0.634, 1.38 -0.51
CE/J m 0.867 0.189   9 0.063 0.218 0.554, 1.11 -0.88
DBA/1J f 1.03 0.224   10 0.0709 0.218 0.736, 1.57 -0.12
DBA/1J m 0.881 0.167   8 0.0592 0.19 0.637, 1.08 -0.85
DBA/2J f 1.02 0.196   8 0.0694 0.192 0.814, 1.4 -0.15
DBA/2J m 1.08 0.214   10 0.0678 0.198 0.789, 1.59 -0.32
FVB/NJ f 0.882 0.328   8 0.116 0.373 0.481, 1.29 -0.53
FVB/NJ m 1.72 0.27   7 0.102 0.157 1.17, 2.02 1.37
I/LnJ f 0.854 0.349   7 0.132 0.409 0.33, 1.34 -0.61
I/LnJ m 1.22 0.55   5 0.246 0.452 0.606, 1.66 0.05
KK/HlJ f 1.32 0.288   8 0.102 0.218 0.851, 1.84 0.67
KK/HlJ m 1.22 0.188   6 0.0769 0.154 0.988, 1.48 0.05
LP/J f 0.456 0.22   8 0.0779 0.483 0.152, 0.827 -1.7
LP/J m 0.807 0.325   8 0.115 0.403 0.543, 1.53 -1.04
NOD/ShiLtJ f 1.41 0.292   8 0.103 0.207 1.05, 1.93 0.92
NOD/ShiLtJ m 1.36 0.234   8 0.0826 0.171 1.09, 1.65 0.42
NON/ShiLtJ f 0.601 0.134   8 0.0475 0.224 0.411, 0.823 -1.3
NON/ShiLtJ m 0.715 0.149   8 0.0527 0.208 0.572, 0.937 -1.28
NZW/LacJ f 0.901 0.147   8 0.0519 0.163 0.634, 1.09 -0.48
NZW/LacJ m 0.953 0.328   8 0.116 0.344 0.544, 1.37 -0.66
PL/J f 0.436 0.147   8 0.052 0.337 0.256, 0.717 -1.76
PL/J m 0.591 0.275   8 0.0973 0.466 0.404, 1.2 -1.61
RIIIS/J f 0.989 0.17   8 0.0602 0.172 0.828, 1.37 -0.24
RIIIS/J m 0.846 0.187   8 0.0662 0.221 0.653, 1.2 -0.94
SJL/J f 0.563 0.2   8 0.0706 0.355 0.35, 0.944 -1.41
SJL/J m 0.63 0.16   8 0.0566 0.254 0.462, 0.955 -1.51
SM/J f 1.11 0.119   8 0.0419 0.107 0.986, 1.29 0.1
SM/J m 1.14 0.165   8 0.0584 0.144 0.911, 1.38 -0.16
SWR/J f 0.529 0.139   8 0.0493 0.263 0.35, 0.732 -1.5
SWR/J m 0.879 0.147   9 0.0489 0.167 0.657, 1.1 -0.85


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.2585 0.101 1.4571 1.0599
129S1/SvImJ m 1.3182 0.101 1.5168 1.1197
A/J f 0.6769 0.101 0.8755 0.4783
A/J m 0.6685 0.101 0.8671 0.4699
AKR/J f 1.2447 0.101 1.4433 1.0462
AKR/J m 1.6163 0.101 1.8148 1.4177
BALB/cByJ f 1.2226 0.101 1.4212 1.024
BALB/cByJ m 1.4526 0.101 1.6512 1.254
BALB/cJ f 1.3318 0.0904 1.5094 1.1542
BALB/cJ m 1.5014 0.0904 1.679 1.3238
BTBR T+ Itpr3tf/J f 1.4012 0.101 1.5998 1.2027
BTBR T+ Itpr3tf/J m 1.65 0.101 1.8486 1.4514
BUB/BnJ f 1.2259 0.108 1.4381 1.0136
BUB/BnJ m 1.0085 0.101 1.2071 0.8099
C3H/HeJ f 0.7861 0.101 0.9847 0.5875
C3H/HeJ m 0.8913 0.101 1.0898 0.6927
C57BL/10J f 1.535 0.101 1.7336 1.3364
C57BL/10J m 1.6271 0.108 1.8394 1.4149
C57BL/6J f 1.3929 0.108 1.6051 1.1806
C57BL/6J m 1.7135 0.0792 1.8693 1.5578
C57BLKS/J f 1.3948 0.0861 1.5642 1.2255
C57BLKS/J m 1.535 0.101 1.7336 1.3364
C57BR/cdJ f 1.8383 0.1166 2.0676 1.609
C57BR/cdJ m 1.6775 0.101 1.8761 1.4789
C57L/J f 1.4125 0.101 1.6111 1.2139
C57L/J m 1.6425 0.101 1.8411 1.4439
CBA/J f 1.4937 0.101 1.6923 1.2952
CBA/J m 1.6163 0.101 1.8148 1.4177
CE/J f 0.8899 0.101 1.0885 0.6913
CE/J m 0.8669 0.0952 1.0541 0.6797
DBA/1J f 1.0297 0.0904 1.2073 0.8521
DBA/1J m 0.8812 0.101 1.0798 0.6827
DBA/2J f 1.0242 0.101 1.2228 0.8257
DBA/2J m 1.0827 0.0904 1.2603 0.9051
FVB/NJ f 0.8817 0.101 1.0803 0.6832
FVB/NJ m 1.72 0.108 1.9323 1.5077
I/LnJ f 0.8544 0.108 1.0667 0.6421
I/LnJ m 1.219 0.1278 1.4702 0.9678
KK/HlJ f 1.3201 0.101 1.5187 1.1215
KK/HlJ m 1.2213 0.1166 1.4506 0.992
LP/J f 0.4562 0.101 0.6548 0.2577
LP/J m 0.807 0.101 1.0056 0.6084
NOD/ShiLtJ f 1.41 0.101 1.6086 1.2114
NOD/ShiLtJ m 1.365 0.101 1.5636 1.1664
NON/ShiLtJ f 0.6012 0.101 0.7998 0.4027
NON/ShiLtJ m 0.7145 0.101 0.9131 0.5159
NZW/LacJ f 0.9009 0.101 1.0995 0.7023
NZW/LacJ m 0.953 0.101 1.1516 0.7544
PL/J f 0.436 0.101 0.6346 0.2374
PL/J m 0.5909 0.101 0.7895 0.3923
RIIIS/J f 0.9888 0.101 1.1873 0.7902
RIIIS/J m 0.8461 0.101 1.0447 0.6475
SJL/J f 0.5626 0.101 0.7612 0.364
SJL/J m 0.63 0.101 0.8286 0.4314
SM/J f 1.107 0.101 1.3056 0.9084
SM/J m 1.1435 0.101 1.3421 0.9449
SWR/J f 0.5293 0.101 0.7278 0.3307
SWR/J m 0.8787 0.0952 1.0659 0.6914


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.2884 0.0714 1.4288 1.148
A/J both 0.6727 0.0714 0.8131 0.5323
AKR/J both 1.4305 0.0714 1.5709 1.2901
BALB/cByJ both 1.3376 0.0714 1.478 1.1972
BALB/cJ both 1.4166 0.0639 1.5422 1.291
BTBR T+ Itpr3tf/J both 1.5256 0.0714 1.666 1.3852
BUB/BnJ both 1.1172 0.0739 1.2625 0.9718
C3H/HeJ both 0.8387 0.0714 0.9791 0.6983
C57BL/10J both 1.5811 0.0739 1.7264 1.4357
C57BL/6J both 1.5532 0.067 1.6849 1.4215
C57BLKS/J both 1.4649 0.0664 1.5954 1.3344
C57BR/cdJ both 1.7579 0.0772 1.9096 1.6063
C57L/J both 1.5275 0.0714 1.6679 1.3871
CBA/J both 1.555 0.0714 1.6954 1.4146
CE/J both 0.8784 0.0694 1.0148 0.7419
DBA/1J both 0.9555 0.0678 1.0887 0.8223
DBA/2J both 1.0535 0.0678 1.1867 0.9203
FVB/NJ both 1.3009 0.0739 1.4462 1.1555
I/LnJ both 1.0367 0.0837 1.2012 0.8723
KK/HlJ both 1.2707 0.0772 1.4224 1.1191
LP/J both 0.6316 0.0714 0.772 0.4912
NOD/ShiLtJ both 1.3875 0.0714 1.5279 1.2471
NON/ShiLtJ both 0.6579 0.0714 0.7983 0.5175
NZW/LacJ both 0.9269 0.0714 1.0674 0.7865
PL/J both 0.5134 0.0714 0.6539 0.373
RIIIS/J both 0.9174 0.0714 1.0579 0.777
SJL/J both 0.5963 0.0714 0.7367 0.4559
SM/J both 1.1253 0.0714 1.2657 0.9848
SWR/J both 0.704 0.0694 0.8404 0.5675




  GWAS USING LINEAR MIXED MODELS