Project measure / variable:   Berndt2   resp_flow_saline

ID, description, units MPD:35154   resp_flow_saline   respiratory flow rate   [mL/kg/s]  saline  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - respiratory flow rate saline



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.915   mL/kg/s 0.984   mL/kg/s
Median of the strain means0.919   mL/kg/s 0.936   mL/kg/s
SD of the strain means± 0.226 ± 0.248
Coefficient of variation (CV)0.247 0.252
Min–max range of strain means0.543   –   1.52   mL/kg/s 0.634   –   1.66   mL/kg/s
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.671 0.671 6.8967 0.009
strain 28 23.8282 0.851 8.7469 < 0.0001
sex:strain 28 2.9038 0.1037 1.0659 0.377
Residuals 412 40.0846 0.0973


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.727 0.184   8 0.065 0.253 0.396, 0.962 -0.83
129S1/SvImJ m 0.771 0.194   8 0.0685 0.251 0.473, 1.05 -0.86
A/J f 0.969 0.163   8 0.0577 0.168 0.743, 1.19 0.24
A/J m 1.04 0.233   8 0.0823 0.224 0.754, 1.4 0.22
AKR/J f 0.919 0.308   8 0.109 0.336 0.549, 1.54 0.02
AKR/J m 0.816 0.217   8 0.0765 0.265 0.536, 1.19 -0.68
BALB/cByJ f 1.16 0.243   8 0.0859 0.209 0.656, 1.39 1.08
BALB/cByJ m 1.35 0.373   8 0.132 0.276 0.98, 2.17 1.47
BALB/cJ f 1.52 0.729   10 0.23 0.479 0.653, 3.31 2.67
BALB/cJ m 1.45 0.402   10 0.127 0.277 0.751, 2.07 1.88
BTBR T+ Itpr3tf/J f 1.29 0.348   8 0.123 0.269 0.744, 1.85 1.66
BTBR T+ Itpr3tf/J m 1.66 0.392   8 0.139 0.236 1.19, 2.27 2.72
BUB/BnJ f 1.07 0.5   7 0.189 0.466 0.613, 1.85 0.69
BUB/BnJ m 1.01 0.284   8 0.1 0.28 0.721, 1.53 0.1
C3H/HeJ f 0.834 0.234   8 0.0826 0.28 0.55, 1.35 -0.36
C3H/HeJ m 0.746 0.166   8 0.0587 0.223 0.556, 0.999 -0.96
C57BL/10J f 1.14 0.427   8 0.151 0.373 0.895, 2.16 1.0
C57BL/10J m 1.21 0.252   7 0.0954 0.209 0.864, 1.59 0.91
C57BL/6J f 0.998 0.343   7 0.13 0.344 0.703, 1.55 0.37
C57BL/6J m 1.21 0.548   13 0.152 0.452 0.676, 2.45 0.91
C57BLKS/J f 0.958 0.272   11 0.0821 0.284 0.586, 1.47 0.19
C57BLKS/J m 0.931 0.148   8 0.0525 0.159 0.707, 1.15 -0.21
C57BR/cdJ f 1.13 0.602   6 0.246 0.531 0.576, 2.26 0.95
C57BR/cdJ m 1.07 0.213   8 0.0752 0.2 0.808, 1.41 0.35
C57L/J f 0.994 0.156   8 0.055 0.157 0.782, 1.26 0.35
C57L/J m 0.936 0.254   8 0.0899 0.272 0.665, 1.37 -0.19
CBA/J f 0.749 0.132   8 0.0466 0.176 0.557, 0.904 -0.73
CBA/J m 0.957 0.273   8 0.0966 0.286 0.66, 1.43 -0.11
CE/J f 1.23 0.539   8 0.19 0.437 0.522, 2.37 1.39
CE/J m 1.12 0.189   9 0.0632 0.169 0.817, 1.42 0.55
DBA/1J f 0.734 0.218   10 0.069 0.297 0.296, 0.973 -0.8
DBA/1J m 0.746 0.202   8 0.0716 0.271 0.489, 1.02 -0.96
DBA/2J f 0.848 0.18   8 0.0635 0.212 0.639, 1.19 -0.29
DBA/2J m 1.01 0.205   10 0.065 0.203 0.748, 1.38 0.1
FVB/NJ f 0.754 0.311   8 0.11 0.413 0.492, 1.34 -0.71
FVB/NJ m 1.15 0.51   7 0.193 0.444 0.548, 2.04 0.67
I/LnJ f 0.733 0.147   7 0.0557 0.201 0.531, 0.953 -0.8
I/LnJ m 0.896 0.117   5 0.0525 0.131 0.756, 1.05 -0.36
KK/HlJ f 1.07 0.46   8 0.162 0.43 0.635, 1.83 0.69
KK/HlJ m 0.906 0.234   6 0.0955 0.258 0.733, 1.37 -0.32
LP/J f 0.543 0.152   8 0.0538 0.28 0.33, 0.803 -1.64
LP/J m 0.835 0.284   8 0.101 0.34 0.558, 1.32 -0.6
NOD/ShiLtJ f 0.662 0.192   8 0.0678 0.289 0.453, 1.05 -1.12
NOD/ShiLtJ m 0.654 0.158   8 0.0558 0.241 0.491, 0.949 -1.33
NON/ShiLtJ f 0.789 0.266   8 0.0942 0.338 0.437, 1.15 -0.55
NON/ShiLtJ m 1.21 0.359   8 0.127 0.297 0.916, 2.04 0.91
NZW/LacJ f 0.725 0.148   8 0.0523 0.204 0.544, 0.94 -0.84
NZW/LacJ m 0.698 0.123   8 0.0434 0.176 0.476, 0.844 -1.15
PL/J f 0.738 0.253   8 0.0895 0.343 0.442, 1.26 -0.78
PL/J m 0.797 0.353   8 0.125 0.443 0.574, 1.63 -0.75
RIIIS/J f 0.983 0.414   8 0.146 0.421 0.626, 1.84 0.3
RIIIS/J m 0.918 0.126   8 0.0444 0.137 0.713, 1.14 -0.27
SJL/J f 0.706 0.0969   8 0.0342 0.137 0.523, 0.85 -0.92
SJL/J m 0.634 0.196   8 0.0691 0.308 0.41, 0.887 -1.41
SM/J f 0.958 0.162   8 0.0572 0.169 0.712, 1.26 0.19
SM/J m 1.14 0.447   8 0.158 0.391 0.676, 1.93 0.63
SWR/J f 0.592 0.166   8 0.0587 0.281 0.446, 0.873 -1.43
SWR/J m 0.671 0.159   9 0.0529 0.237 0.415, 0.885 -1.26


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.7266 0.1103 0.9434 0.5098
129S1/SvImJ m 0.7713 0.1103 0.988 0.5545
A/J f 0.9687 0.1103 1.1855 0.752
A/J m 1.0379 0.1103 1.2547 0.8211
AKR/J f 0.9186 0.1103 1.1354 0.7018
AKR/J m 0.816 0.1103 1.0328 0.5992
BALB/cByJ f 1.1642 0.1103 1.381 0.9475
BALB/cByJ m 1.355 0.1103 1.5718 1.1382
BALB/cJ f 1.52 0.0986 1.7139 1.3261
BALB/cJ m 1.4501 0.0986 1.644 1.2562
BTBR T+ Itpr3tf/J f 1.2946 0.1103 1.5114 1.0778
BTBR T+ Itpr3tf/J m 1.6625 0.1103 1.8793 1.4457
BUB/BnJ f 1.0729 0.1179 1.3046 0.8411
BUB/BnJ m 1.0138 0.1103 1.2305 0.797
C3H/HeJ f 0.834 0.1103 1.0508 0.6172
C3H/HeJ m 0.7463 0.1103 0.963 0.5295
C57BL/10J f 1.1432 0.1103 1.36 0.9265
C57BL/10J m 1.2091 0.1179 1.4409 0.9774
C57BL/6J f 0.9983 0.1179 1.23 0.7665
C57BL/6J m 1.2145 0.0865 1.3845 1.0444
C57BLKS/J f 0.9585 0.094 1.1433 0.7736
C57BLKS/J m 0.9311 0.1103 1.1479 0.7143
C57BR/cdJ f 1.134 0.1273 1.3843 0.8837
C57BR/cdJ m 1.0654 0.1103 1.2822 0.8486
C57L/J f 0.9939 0.1103 1.2107 0.7771
C57L/J m 0.9356 0.1103 1.1524 0.7188
CBA/J f 0.7491 0.1103 0.9659 0.5323
CBA/J m 0.9565 0.1103 1.1733 0.7397
CE/J f 1.2325 0.1103 1.4493 1.0157
CE/J m 1.1181 0.104 1.3225 0.9137
DBA/1J f 0.7342 0.0986 0.9281 0.5403
DBA/1J m 0.7463 0.1103 0.963 0.5295
DBA/2J f 0.8482 0.1103 1.065 0.6315
DBA/2J m 1.0102 0.0986 1.2041 0.8163
FVB/NJ f 0.754 0.1103 0.9708 0.5372
FVB/NJ m 1.1493 0.1179 1.381 0.9175
I/LnJ f 0.7331 0.1179 0.9649 0.5014
I/LnJ m 0.8956 0.1395 1.1698 0.6214
KK/HlJ f 1.0679 0.1103 1.2847 0.8511
KK/HlJ m 0.9062 0.1273 1.1565 0.6558
LP/J f 0.543 0.1103 0.7598 0.3262
LP/J m 0.8351 0.1103 1.0519 0.6183
NOD/ShiLtJ f 0.6621 0.1103 0.8789 0.4453
NOD/ShiLtJ m 0.654 0.1103 0.8708 0.4372
NON/ShiLtJ f 0.7887 0.1103 1.0055 0.572
NON/ShiLtJ m 1.21 0.1103 1.4268 0.9932
NZW/LacJ f 0.7255 0.1103 0.9423 0.5087
NZW/LacJ m 0.6979 0.1103 0.9147 0.4811
PL/J f 0.7384 0.1103 0.9552 0.5216
PL/J m 0.7968 0.1103 1.0135 0.58
RIIIS/J f 0.9826 0.1103 1.1994 0.7658
RIIIS/J m 0.9179 0.1103 1.1347 0.7011
SJL/J f 0.7064 0.1103 0.9232 0.4896
SJL/J m 0.6342 0.1103 0.851 0.4175
SM/J f 0.9582 0.1103 1.175 0.7415
SM/J m 1.1433 0.1103 1.36 0.9265
SWR/J f 0.5919 0.1103 0.8087 0.3751
SWR/J m 0.6709 0.104 0.8753 0.4665


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.7489 0.078 0.9022 0.5957
A/J both 1.0033 0.078 1.1566 0.85
AKR/J both 0.8673 0.078 1.0206 0.714
BALB/cByJ both 1.2596 0.078 1.4129 1.1063
BALB/cJ both 1.485 0.0697 1.6222 1.3479
BTBR T+ Itpr3tf/J both 1.4786 0.078 1.6318 1.3253
BUB/BnJ both 1.0433 0.0807 1.202 0.8846
C3H/HeJ both 0.7901 0.078 0.9434 0.6368
C57BL/10J both 1.1762 0.0807 1.3349 1.0175
C57BL/6J both 1.1064 0.0731 1.2501 0.9626
C57BLKS/J both 0.9448 0.0725 1.0872 0.8023
C57BR/cdJ both 1.0997 0.0842 1.2653 0.9341
C57L/J both 0.9647 0.078 1.118 0.8115
CBA/J both 0.8528 0.078 1.0061 0.6995
CE/J both 1.1753 0.0758 1.3243 1.0263
DBA/1J both 0.7402 0.074 0.8856 0.5948
DBA/2J both 0.9292 0.074 1.0746 0.7838
FVB/NJ both 0.9516 0.0807 1.1103 0.793
I/LnJ both 0.8144 0.0913 0.9939 0.6349
KK/HlJ both 0.987 0.0842 1.1526 0.8215
LP/J both 0.6891 0.078 0.8423 0.5358
NOD/ShiLtJ both 0.6581 0.078 0.8113 0.5048
NON/ShiLtJ both 0.9994 0.078 1.1527 0.8461
NZW/LacJ both 0.7117 0.078 0.865 0.5584
PL/J both 0.7676 0.078 0.9208 0.6143
RIIIS/J both 0.9502 0.078 1.1035 0.797
SJL/J both 0.6703 0.078 0.8236 0.517
SM/J both 1.0507 0.078 1.204 0.8975
SWR/J both 0.6314 0.0758 0.7804 0.4824




  GWAS USING LINEAR MIXED MODELS