Project measure / variable:   Berndt2   insp_flow_saline

ID, description, units MPD:35141   insp_flow_saline   inspiratory flow rate   [mL/kg/s]  saline  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - inspiratory flow rate saline



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means3.07   mL/kg/s 3.23   mL/kg/s
Median of the strain means2.86   mL/kg/s 3.32   mL/kg/s
SD of the strain means± 0.697 ± 0.735
Coefficient of variation (CV)0.227 0.228
Min–max range of strain means1.90   –   4.85   mL/kg/s 1.87   –   4.74   mL/kg/s
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3.7225 3.7225 6.0563 0.0143
strain 28 219.4075 7.836 12.7488 < 0.0001
sex:strain 28 26.8778 0.9599 1.5617 0.036
Residuals 412 253.2342 0.6146


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.78 0.341   8 0.121 0.123 2.04, 3.17 -0.41
129S1/SvImJ m 2.64 0.495   8 0.175 0.187 1.66, 3.17 -0.8
A/J f 3.35 0.461   8 0.163 0.138 2.45, 3.94 0.41
A/J m 3.45 0.62   8 0.219 0.18 2.53, 4.32 0.3
AKR/J f 2.92 0.744   8 0.263 0.255 1.95, 4.14 -0.21
AKR/J m 2.86 0.747   8 0.264 0.262 1.72, 3.84 -0.5
BALB/cByJ f 4.05 0.768   8 0.272 0.19 2.43, 4.87 1.41
BALB/cByJ m 4.41 1.06   8 0.375 0.241 3.41, 6.71 1.61
BALB/cJ f 4.85 1.3   10 0.413 0.269 2.84, 7.69 2.56
BALB/cJ m 4.52 0.867   10 0.274 0.192 3.05, 5.67 1.76
BTBR T+ Itpr3tf/J f 4.0 0.766   8 0.271 0.191 2.52, 4.83 1.34
BTBR T+ Itpr3tf/J m 4.74 0.666   8 0.235 0.141 3.87, 5.93 2.06
BUB/BnJ f 3.52 1.37   7 0.519 0.39 1.95, 5.41 0.65
BUB/BnJ m 3.32 0.903   8 0.319 0.272 2.28, 4.82 0.13
C3H/HeJ f 2.98 0.542   8 0.192 0.182 2.21, 4.08 -0.13
C3H/HeJ m 2.66 0.544   8 0.192 0.205 1.99, 3.47 -0.77
C57BL/10J f 4.03 0.949   8 0.335 0.235 3.4, 6.27 1.38
C57BL/10J m 3.86 0.781   7 0.295 0.202 2.72, 5.26 0.86
C57BL/6J f 3.38 0.757   7 0.286 0.224 2.58, 4.29 0.45
C57BL/6J m 4.22 1.34   13 0.372 0.318 2.72, 7.18 1.35
C57BLKS/J f 3.26 0.613   11 0.185 0.188 2.28, 3.97 0.28
C57BLKS/J m 3.64 0.638   8 0.226 0.175 2.69, 4.42 0.56
C57BR/cdJ f 3.47 1.12   6 0.458 0.323 2.35, 5.54 0.58
C57BR/cdJ m 3.15 0.511   8 0.18 0.162 2.36, 3.71 -0.11
C57L/J f 3.51 0.25   8 0.0884 0.0713 3.22, 3.94 0.64
C57L/J m 3.52 0.894   8 0.316 0.253 2.3, 5.25 0.4
CBA/J f 2.73 0.485   8 0.171 0.178 2.03, 3.35 -0.48
CBA/J m 3.32 0.781   8 0.276 0.235 2.11, 4.25 0.13
CE/J f 3.69 1.28   8 0.453 0.346 2.11, 6.45 0.89
CE/J m 3.54 0.456   9 0.152 0.129 2.94, 4.31 0.43
DBA/1J f 2.25 0.592   10 0.187 0.263 1.11, 2.9 -1.17
DBA/1J m 2.41 0.65   8 0.23 0.27 1.64, 3.26 -1.11
DBA/2J f 2.67 0.407   8 0.144 0.152 2.16, 3.51 -0.57
DBA/2J m 2.99 0.579   10 0.183 0.194 2.16, 4.02 -0.32
FVB/NJ f 2.38 0.957   8 0.338 0.402 1.56, 4.22 -0.99
FVB/NJ m 3.64 1.71   7 0.646 0.47 1.82, 6.56 0.56
I/LnJ f 2.79 0.481   7 0.182 0.172 1.88, 3.35 -0.4
I/LnJ m 3.15 0.257   5 0.115 0.0818 2.89, 3.57 -0.11
KK/HlJ f 4.0 1.35   8 0.478 0.339 2.61, 6.52 1.34
KK/HlJ m 3.34 0.668   6 0.273 0.2 2.43, 4.36 0.15
LP/J f 2.0 0.447   8 0.158 0.224 1.4, 2.56 -1.53
LP/J m 2.75 0.633   8 0.224 0.23 2.16, 3.89 -0.65
NOD/ShiLtJ f 2.71 0.569   8 0.201 0.21 2.09, 3.84 -0.51
NOD/ShiLtJ m 2.45 0.302   8 0.107 0.123 2.12, 2.93 -1.06
NON/ShiLtJ f 2.86 0.806   8 0.285 0.282 1.66, 3.95 -0.3
NON/ShiLtJ m 3.95 0.885   8 0.313 0.224 3.07, 5.88 0.98
NZW/LacJ f 2.42 0.599   8 0.212 0.248 1.71, 3.3 -0.93
NZW/LacJ m 2.04 0.307   8 0.109 0.151 1.64, 2.63 -1.61
PL/J f 2.76 0.447   8 0.158 0.162 2.07, 3.39 -0.44
PL/J m 2.81 0.658   8 0.233 0.234 2.24, 4.16 -0.57
RIIIS/J f 2.73 0.929   8 0.328 0.341 1.97, 4.77 -0.48
RIIIS/J m 2.72 0.374   8 0.132 0.138 2.3, 3.44 -0.69
SJL/J f 2.34 0.373   8 0.132 0.16 1.66, 2.78 -1.04
SJL/J m 1.87 0.687   8 0.243 0.367 1.13, 2.81 -1.85
SM/J f 2.62 0.474   8 0.168 0.181 1.93, 3.6 -0.64
SM/J m 3.47 1.04   8 0.368 0.3 2.23, 4.97 0.33
SWR/J f 1.9 0.576   8 0.203 0.303 1.31, 2.85 -1.67
SWR/J m 2.15 0.616   9 0.205 0.287 1.24, 3.0 -1.46


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.7775 0.2772 3.3224 2.2326
129S1/SvImJ m 2.6413 0.2772 3.1861 2.0964
A/J f 3.3475 0.2772 3.8924 2.8026
A/J m 3.4525 0.2772 3.9974 2.9076
AKR/J f 2.9213 0.2772 3.4661 2.3764
AKR/J m 2.855 0.2772 3.3999 2.3101
BALB/cByJ f 4.05 0.2772 4.5949 3.5051
BALB/cByJ m 4.41 0.2772 4.9549 3.8651
BALB/cJ f 4.852 0.2479 5.3393 4.3647
BALB/cJ m 4.519 0.2479 5.0063 4.0317
BTBR T+ Itpr3tf/J f 3.9988 0.2772 4.5436 3.4539
BTBR T+ Itpr3tf/J m 4.7375 0.2772 5.2824 4.1926
BUB/BnJ f 3.5214 0.2963 4.1039 2.9389
BUB/BnJ m 3.3238 0.2772 3.8686 2.7789
C3H/HeJ f 2.9775 0.2772 3.5224 2.4326
C3H/HeJ m 2.6575 0.2772 3.2024 2.1126
C57BL/10J f 4.0312 0.2772 4.5761 3.4864
C57BL/10J m 3.86 0.2963 4.4425 3.2775
C57BL/6J f 3.3829 0.2963 3.9653 2.8004
C57BL/6J m 4.2238 0.2174 4.6513 3.7964
C57BLKS/J f 3.2582 0.2364 3.7228 2.7935
C57BLKS/J m 3.635 0.2772 4.1799 3.0901
C57BR/cdJ f 3.4683 0.3201 4.0975 2.8392
C57BR/cdJ m 3.1488 0.2772 3.6936 2.6039
C57L/J f 3.5087 0.2772 4.0536 2.9639
C57L/J m 3.525 0.2772 4.0699 2.9801
CBA/J f 2.7288 0.2772 3.2736 2.1839
CBA/J m 3.3188 0.2772 3.8636 2.7739
CE/J f 3.695 0.2772 4.2399 3.1501
CE/J m 3.5422 0.2613 4.0559 3.0285
DBA/1J f 2.248 0.2479 2.7353 1.7607
DBA/1J m 2.41 0.2772 2.9549 1.8651
DBA/2J f 2.6737 0.2772 3.2186 2.1289
DBA/2J m 2.991 0.2479 3.4783 2.5037
FVB/NJ f 2.3825 0.2772 2.9274 1.8376
FVB/NJ m 3.6357 0.2963 4.2182 3.0532
I/LnJ f 2.79 0.2963 3.3725 2.2075
I/LnJ m 3.146 0.3506 3.8352 2.4568
KK/HlJ f 3.9963 0.2772 4.5411 3.4514
KK/HlJ m 3.3433 0.3201 3.9725 2.7142
LP/J f 1.995 0.2772 2.5399 1.4501
LP/J m 2.755 0.2772 3.2999 2.2101
NOD/ShiLtJ f 2.71 0.2772 3.2549 2.1651
NOD/ShiLtJ m 2.45 0.2772 2.9949 1.9051
NON/ShiLtJ f 2.86 0.2772 3.4049 2.3151
NON/ShiLtJ m 3.9538 0.2772 4.4986 3.4089
NZW/LacJ f 2.4175 0.2772 2.9624 1.8726
NZW/LacJ m 2.04 0.2772 2.5849 1.4951
PL/J f 2.7625 0.2772 3.3074 2.2176
PL/J m 2.81 0.2772 3.3549 2.2651
RIIIS/J f 2.7262 0.2772 3.2711 2.1814
RIIIS/J m 2.7188 0.2772 3.2636 2.1739
SJL/J f 2.3387 0.2772 2.8836 1.7939
SJL/J m 1.8725 0.2772 2.4174 1.3276
SM/J f 2.615 0.2772 3.1599 2.0701
SM/J m 3.47 0.2772 4.0149 2.9251
SWR/J f 1.8988 0.2772 2.4436 1.3539
SWR/J m 2.1478 0.2613 2.6615 1.6341


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.7094 0.196 3.0947 2.3241
A/J both 3.4 0.196 3.7853 3.0147
AKR/J both 2.8881 0.196 3.2734 2.5028
BALB/cByJ both 4.23 0.196 4.6153 3.8447
BALB/cJ both 4.6855 0.1753 5.0301 4.3409
BTBR T+ Itpr3tf/J both 4.3681 0.196 4.7534 3.9828
BUB/BnJ both 3.4226 0.2029 3.8214 3.0238
C3H/HeJ both 2.8175 0.196 3.2028 2.4322
C57BL/10J both 3.9456 0.2029 4.3444 3.5468
C57BL/6J both 3.8034 0.1838 4.1646 3.4421
C57BLKS/J both 3.4466 0.1821 3.8046 3.0885
C57BR/cdJ both 3.3085 0.2117 3.7247 2.8924
C57L/J both 3.5169 0.196 3.9022 3.1316
CBA/J both 3.0238 0.196 3.409 2.6385
CE/J both 3.6186 0.1905 3.993 3.2442
DBA/1J both 2.329 0.1859 2.6945 1.9635
DBA/2J both 2.8324 0.1859 3.1979 2.4669
FVB/NJ both 3.0091 0.2029 3.4079 2.6103
I/LnJ both 2.968 0.2295 3.4192 2.5168
KK/HlJ both 3.6698 0.2117 4.0859 3.2536
LP/J both 2.375 0.196 2.7603 1.9897
NOD/ShiLtJ both 2.58 0.196 2.9653 2.1947
NON/ShiLtJ both 3.4069 0.196 3.7922 3.0216
NZW/LacJ both 2.2288 0.196 2.614 1.8435
PL/J both 2.7863 0.196 3.1715 2.401
RIIIS/J both 2.7225 0.196 3.1078 2.3372
SJL/J both 2.1056 0.196 2.4909 1.7203
SM/J both 3.0425 0.196 3.4278 2.6572
SWR/J both 2.0233 0.1905 2.3977 1.6488




  GWAS USING LINEAR MIXED MODELS