Project measure / variable:   Berndt2   insp_flow_mch10

ID, description, units MPD:35143   insp_flow_mch10   inspiratory flow rate   [mL/kg/s]  10 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - inspiratory flow rate 10 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means1.30   mL/kg/s 1.61   mL/kg/s
Median of the strain means1.25   mL/kg/s 1.52   mL/kg/s
SD of the strain means± 0.533 ± 0.612
Coefficient of variation (CV)0.408 0.381
Min–max range of strain means0.508   –   2.95   mL/kg/s 0.741   –   3.37   mL/kg/s
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 9.2788 9.2788 46.8945 < 0.0001
strain 28 143.102 5.1108 25.8295 < 0.0001
sex:strain 28 9.3082 0.3324 1.6801 0.0177
Residuals 412 81.521 0.1979


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.934 0.474   8 0.168 0.508 0.504, 1.91 -0.7
129S1/SvImJ m 1.35 0.496   8 0.175 0.368 0.651, 1.87 -0.42
A/J f 1.53 0.39   8 0.138 0.255 1.09, 2.01 0.42
A/J m 1.52 0.282   8 0.0996 0.185 1.09, 2.03 -0.14
AKR/J f 1.69 0.825   8 0.292 0.489 0.858, 3.4 0.72
AKR/J m 1.75 0.492   8 0.174 0.28 1.01, 2.45 0.23
BALB/cByJ f 1.82 0.378   8 0.134 0.207 1.43, 2.59 0.97
BALB/cByJ m 1.82 0.465   8 0.164 0.255 0.816, 2.39 0.35
BALB/cJ f 2.39 0.845   10 0.267 0.353 1.25, 4.0 2.04
BALB/cJ m 2.78 0.605   10 0.191 0.218 1.75, 3.59 1.92
BTBR T+ Itpr3tf/J f 2.95 0.573   8 0.203 0.194 2.28, 3.72 3.09
BTBR T+ Itpr3tf/J m 3.37 0.612   8 0.216 0.182 2.0, 4.13 2.88
BUB/BnJ f 1.27 0.318   7 0.12 0.25 0.808, 1.69 -0.07
BUB/BnJ m 1.75 0.454   8 0.16 0.259 1.26, 2.47 0.23
C3H/HeJ f 0.908 0.166   8 0.0585 0.182 0.587, 1.08 -0.74
C3H/HeJ m 0.99 0.44   8 0.156 0.444 0.399, 1.92 -1.01
C57BL/10J f 1.41 0.259   8 0.0916 0.183 1.1, 1.92 0.2
C57BL/10J m 2.44 0.454   7 0.171 0.186 1.95, 3.33 1.36
C57BL/6J f 1.08 0.213   7 0.0805 0.197 0.792, 1.28 -0.42
C57BL/6J m 1.3 0.506   13 0.14 0.389 0.724, 2.39 -0.5
C57BLKS/J f 1.43 0.325   11 0.0981 0.227 1.08, 2.08 0.23
C57BLKS/J m 2.04 1.0   8 0.354 0.492 0.675, 3.1 0.71
C57BR/cdJ f 1.3 0.553   6 0.226 0.424 0.821, 2.14 -0.01
C57BR/cdJ m 1.77 0.606   8 0.214 0.342 1.09, 3.01 0.27
C57L/J f 1.23 0.326   8 0.115 0.265 0.801, 1.65 -0.14
C57L/J m 2.03 0.582   8 0.206 0.287 1.12, 2.96 0.69
CBA/J f 1.46 0.184   8 0.0652 0.127 1.22, 1.75 0.29
CBA/J m 1.55 0.34   8 0.12 0.219 1.17, 2.08 -0.09
CE/J f 0.936 0.29   8 0.103 0.31 0.481, 1.33 -0.69
CE/J m 1.31 0.439   9 0.146 0.335 0.806, 2.17 -0.49
DBA/1J f 1.49 0.441   10 0.139 0.295 0.839, 2.38 0.35
DBA/1J m 1.73 0.414   8 0.146 0.24 0.966, 2.25 0.2
DBA/2J f 1.33 0.255   8 0.0902 0.192 0.858, 1.63 0.05
DBA/2J m 1.25 0.241   10 0.0762 0.193 0.851, 1.73 -0.58
FVB/NJ f 1.03 0.181   8 0.0641 0.176 0.782, 1.25 -0.52
FVB/NJ m 2.12 0.572   7 0.216 0.27 1.32, 3.02 0.84
I/LnJ f 1.11 0.325   7 0.123 0.292 0.664, 1.46 -0.37
I/LnJ m 1.38 0.492   5 0.22 0.355 0.999, 2.23 -0.37
KK/HlJ f 1.48 0.357   8 0.126 0.241 1.11, 2.26 0.33
KK/HlJ m 1.74 0.652   6 0.266 0.374 0.778, 2.7 0.22
LP/J f 0.638 0.194   8 0.0686 0.304 0.413, 0.923 -1.25
LP/J m 0.849 0.411   8 0.145 0.484 0.624, 1.85 -1.24
NOD/ShiLtJ f 1.23 0.334   8 0.118 0.272 0.845, 1.76 -0.14
NOD/ShiLtJ m 1.49 0.492   8 0.174 0.33 0.886, 2.15 -0.19
NON/ShiLtJ f 0.508 0.0952   8 0.0337 0.187 0.37, 0.669 -1.5
NON/ShiLtJ m 0.834 0.33   8 0.117 0.396 0.494, 1.37 -1.26
NZW/LacJ f 1.17 0.267   8 0.0944 0.228 0.645, 1.58 -0.25
NZW/LacJ m 1.26 0.412   8 0.146 0.328 0.858, 2.13 -0.57
PL/J f 0.534 0.178   8 0.0631 0.334 0.313, 0.748 -1.45
PL/J m 0.751 0.155   8 0.0547 0.206 0.596, 1.02 -1.4
RIIIS/J f 1.25 0.237   8 0.0837 0.19 0.972, 1.74 -0.1
RIIIS/J m 1.23 0.223   8 0.0789 0.182 0.944, 1.51 -0.62
SJL/J f 0.782 0.247   8 0.0873 0.316 0.53, 1.28 -0.98
SJL/J m 0.741 0.248   8 0.0876 0.334 0.479, 1.23 -1.42
SM/J f 2.13 0.539   8 0.191 0.253 1.48, 2.81 1.55
SM/J m 2.35 0.661   8 0.234 0.281 1.61, 3.37 1.21
SWR/J f 0.824 0.235   8 0.083 0.285 0.517, 1.12 -0.9
SWR/J m 1.13 0.392   9 0.131 0.346 0.693, 1.91 -0.78


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.934 0.1573 1.2431 0.6249
129S1/SvImJ m 1.3501 0.1573 1.6593 1.041
A/J f 1.53 0.1573 1.8391 1.2209
A/J m 1.5213 0.1573 1.8304 1.2121
AKR/J f 1.6879 0.1573 1.997 1.3787
AKR/J m 1.7538 0.1573 2.0629 1.4446
BALB/cByJ f 1.8225 0.1573 2.1316 1.5134
BALB/cByJ m 1.8245 0.1573 2.1336 1.5154
BALB/cJ f 2.394 0.1407 2.6705 2.1175
BALB/cJ m 2.775 0.1407 3.0515 2.4985
BTBR T+ Itpr3tf/J f 2.95 0.1573 3.2591 2.6409
BTBR T+ Itpr3tf/J m 3.3675 0.1573 3.6766 3.0584
BUB/BnJ f 1.274 0.1681 1.6045 0.9435
BUB/BnJ m 1.7488 0.1573 2.0579 1.4396
C3H/HeJ f 0.9075 0.1573 1.2166 0.5984
C3H/HeJ m 0.9904 0.1573 1.2995 0.6812
C57BL/10J f 1.4138 0.1573 1.7229 1.1046
C57BL/10J m 2.4414 0.1681 2.7719 2.1109
C57BL/6J f 1.0793 0.1681 1.4098 0.7488
C57BL/6J m 1.3018 0.1234 1.5444 1.0593
C57BLKS/J f 1.4327 0.1341 1.6964 1.1691
C57BLKS/J m 2.0386 0.1573 2.3478 1.7295
C57BR/cdJ f 1.3033 0.1816 1.6603 0.9464
C57BR/cdJ m 1.7713 0.1573 2.0804 1.4621
C57L/J f 1.2307 0.1573 1.5399 0.9216
C57L/J m 2.0275 0.1573 2.3366 1.7184
CBA/J f 1.455 0.1573 1.7641 1.1459
CBA/J m 1.5488 0.1573 1.8579 1.2396
CE/J f 0.9365 0.1573 1.2456 0.6274
CE/J m 1.3111 0.1483 1.6026 1.0196
DBA/1J f 1.4925 0.1407 1.769 1.216
DBA/1J m 1.727 0.1573 2.0361 1.4179
DBA/2J f 1.3322 0.1573 1.6414 1.0231
DBA/2J m 1.2481 0.1407 1.5246 0.9716
FVB/NJ f 1.0275 0.1573 1.3366 0.7184
FVB/NJ m 2.1229 0.1681 2.4534 1.7924
I/LnJ f 1.1121 0.1681 1.4426 0.7816
I/LnJ m 1.3838 0.1989 1.7748 0.9928
KK/HlJ f 1.4825 0.1573 1.7916 1.1734
KK/HlJ m 1.7413 0.1816 2.0983 1.3844
LP/J f 0.6375 0.1573 0.9466 0.3284
LP/J m 0.8485 0.1573 1.1576 0.5394
NOD/ShiLtJ f 1.2291 0.1573 1.5383 0.92
NOD/ShiLtJ m 1.4895 0.1573 1.7986 1.1804
NON/ShiLtJ f 0.5084 0.1573 0.8175 0.1992
NON/ShiLtJ m 0.8337 0.1573 1.1429 0.5246
NZW/LacJ f 1.1706 0.1573 1.4798 0.8615
NZW/LacJ m 1.2564 0.1573 1.5655 0.9472
PL/J f 0.534 0.1573 0.8431 0.2249
PL/J m 0.7508 0.1573 1.0599 0.4416
RIIIS/J f 1.249 0.1573 1.5581 0.9399
RIIIS/J m 1.2299 0.1573 1.539 0.9207
SJL/J f 0.7819 0.1573 1.091 0.4727
SJL/J m 0.7407 0.1573 1.0499 0.4316
SM/J f 2.1287 0.1573 2.4379 1.8196
SM/J m 2.3525 0.1573 2.6616 2.0434
SWR/J f 0.8241 0.1573 1.1333 0.515
SWR/J m 1.1342 0.1483 1.4257 0.8428


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.1421 0.1112 1.3607 0.9235
A/J both 1.5256 0.1112 1.7442 1.307
AKR/J both 1.7208 0.1112 1.9394 1.5022
BALB/cByJ both 1.8235 0.1112 2.0421 1.6049
BALB/cJ both 2.5845 0.0995 2.78 2.389
BTBR T+ Itpr3tf/J both 3.1587 0.1112 3.3774 2.9401
BUB/BnJ both 1.5114 0.1151 1.7376 1.2851
C3H/HeJ both 0.9489 0.1112 1.1675 0.7303
C57BL/10J both 1.9276 0.1151 2.1539 1.7013
C57BL/6J both 1.1906 0.1043 1.3955 0.9856
C57BLKS/J both 1.7357 0.1033 1.9388 1.5325
C57BR/cdJ both 1.5373 0.1201 1.7734 1.3012
C57L/J both 1.6291 0.1112 1.8477 1.4105
CBA/J both 1.5019 0.1112 1.7205 1.2833
CE/J both 1.1238 0.1081 1.3362 0.9114
DBA/1J both 1.6097 0.1055 1.8171 1.4024
DBA/2J both 1.2902 0.1055 1.4976 1.0828
FVB/NJ both 1.5752 0.1151 1.8015 1.3489
I/LnJ both 1.248 0.1302 1.504 0.992
KK/HlJ both 1.6119 0.1201 1.848 1.3758
LP/J both 0.743 0.1112 0.9616 0.5244
NOD/ShiLtJ both 1.3593 0.1112 1.5779 1.1407
NON/ShiLtJ both 0.6711 0.1112 0.8897 0.4525
NZW/LacJ both 1.2135 0.1112 1.4321 0.9949
PL/J both 0.6424 0.1112 0.861 0.4238
RIIIS/J both 1.2394 0.1112 1.458 1.0208
SJL/J both 0.7613 0.1112 0.9799 0.5427
SM/J both 2.2406 0.1112 2.4592 2.022
SWR/J both 0.9792 0.1081 1.1916 0.7667




  GWAS USING LINEAR MIXED MODELS