Phenotype measure:   Berndt2   tot_respi_slope


  STRAIN COMPARISON PLOT
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Berndt2 - respiratory cycle response index



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.000862   s 0.00288   s
Median of the strain means-0.0348   s -0.0146   s
SD of the strain means± 0.149 ± 0.170
Coefficient of variation (CV)173 59.1
Min–max range of strain means-0.313   –   0.380   s -0.222   –   0.455   s
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0002 0.0002 0.0049 0.9444
strain 28 9.9558 0.3556 9.4305 < 0.0001
sex:strain 28 1.5608 0.0557 1.4785 0.0575
Residuals 412 15.5339 0.0377


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f -0.145 0.246   8 0.087 -1.7 -0.418, 0.218 -0.98
129S1/SvImJ m -0.146 0.257   8 0.0908 -1.76 -0.477, 0.228 -0.88
A/J f 0.38 0.205   8 0.0725 0.54 0.128, 0.589 2.54
A/J m 0.455 0.131   8 0.0465 0.289 0.312, 0.667 2.66
AKR/J f 0.0145 0.0967   8 0.0342 6.67 -0.15, 0.176 0.09
AKR/J m -0.217 0.155   8 0.0548 -0.715 -0.427, 0.014 -1.29
BALB/cByJ f -0.0406 0.157   8 0.0554 -3.86 -0.293, 0.245 -0.28
BALB/cByJ m -0.125 0.0855   8 0.0302 -0.682 -0.231, 0.017 -0.75
BALB/cJ f -0.0874 0.106   10 0.0334 -1.21 -0.22, 0.063 -0.59
BALB/cJ m -0.0645 0.0819   10 0.0259 -1.27 -0.181, 0.104 -0.4
BTBR T+ Itpr3tf/J f 0.376 0.314   8 0.111 0.836 -0.382, 0.571 2.52
BTBR T+ Itpr3tf/J m 0.39 0.168   8 0.0592 0.43 0.166, 0.714 2.28
BUB/BnJ f 0.0286 0.285   7 0.108 9.98 -0.481, 0.389 0.19
BUB/BnJ m 0.0483 0.261   8 0.0925 5.42 -0.281, 0.392 0.27
C3H/HeJ f -0.0601 0.292   8 0.103 -4.85 -0.411, 0.324 -0.41
C3H/HeJ m 0.0391 0.212   8 0.075 5.42 -0.261, 0.276 0.21
C57BL/10J f -0.0832 0.107   8 0.0377 -1.28 -0.236, 0.125 -0.56
C57BL/10J m 0.0544 0.114   7 0.043 2.09 -0.073, 0.246 0.3
C57BL/6J f -0.168 0.136   7 0.0514 -0.809 -0.357, 0.007 -1.13
C57BL/6J m -0.185 0.118   13 0.0326 -0.636 -0.375, -0.05 -1.11
C57BLKS/J f -0.128 0.142   11 0.0427 -1.11 -0.312, 0.105 -0.86
C57BLKS/J m -0.0477 0.238   8 0.0841 -4.98 -0.419, 0.303 -0.3
C57BR/cdJ f -0.114 0.137   6 0.056 -1.21 -0.274, 0.08 -0.77
C57BR/cdJ m -0.0571 0.146   8 0.0517 -2.56 -0.241, 0.145 -0.35
C57L/J f -0.0813 0.0857   8 0.0303 -1.05 -0.169, 0.065 -0.55
C57L/J m -0.0884 0.105   8 0.0371 -1.19 -0.246, 0.056 -0.54
CBA/J f -0.0781 0.0963   8 0.0341 -1.23 -0.207, 0.058 -0.53
CBA/J m -0.131 0.132   8 0.0466 -1.01 -0.314, 0.076 -0.79
CE/J f -0.0504 0.254   8 0.0898 -5.04 -0.599, 0.164 -0.34
CE/J m 0.0171 0.209   9 0.0697 12.2 -0.411, 0.287 0.08
DBA/1J f -0.0348 0.171   10 0.0542 -4.92 -0.232, 0.322 -0.24
DBA/1J m 0.325 0.163   8 0.0578 0.503 0.088, 0.538 1.89
DBA/2J f 0.0557 0.146   8 0.0516 2.62 -0.137, 0.268 0.37
DBA/2J m -0.0132 0.228   10 0.0719 -17.2 -0.442, 0.232 -0.09
FVB/NJ f -0.0576 0.201   8 0.0711 -3.49 -0.329, 0.24 -0.39
FVB/NJ m -0.129 0.172   7 0.065 -1.34 -0.418, 0.097 -0.78
I/LnJ f 0.0657 0.193   7 0.073 2.94 -0.184, 0.296 0.44
I/LnJ m 0.137 0.337   5 0.151 2.47 -0.149, 0.663 0.79
KK/HlJ f -0.0929 0.162   8 0.0574 -1.75 -0.289, 0.13 -0.63
KK/HlJ m -0.135 0.221   6 0.0902 -1.63 -0.511, 0.115 -0.81
LP/J f 0.00937 0.286   8 0.101 30.5 -0.359, 0.585 0.06
LP/J m -0.189 0.173   8 0.0612 -0.918 -0.536, 0.017 -1.13
NOD/ShiLtJ f -0.313 0.199   8 0.0703 -0.636 -0.464, 0.13 -2.11
NOD/ShiLtJ m -0.222 0.304   8 0.107 -1.37 -0.531, 0.298 -1.32
NON/ShiLtJ f 0.176 0.234   8 0.0828 1.33 -0.094, 0.51 1.18
NON/ShiLtJ m 0.114 0.133   8 0.0469 1.16 -0.166, 0.263 0.65
NZW/LacJ f 0.127 0.138   8 0.0487 1.09 -0.053, 0.303 0.85
NZW/LacJ m -0.0476 0.155   8 0.0546 -3.25 -0.255, 0.235 -0.3
PL/J f 0.217 0.193   8 0.0681 0.889 -0.015, 0.475 1.45
PL/J m 0.0659 0.269   8 0.0951 4.08 -0.413, 0.437 0.37
RIIIS/J f -0.0227 0.171   8 0.0604 -7.51 -0.398, 0.099 -0.16
RIIIS/J m 0.0624 0.124   8 0.0438 1.99 -0.172, 0.166 0.35
SJL/J f 0.00463 0.288   8 0.102 62.3 -0.359, 0.376 0.03
SJL/J m -0.0146 0.19   8 0.0672 -13.0 -0.167, 0.304 -0.1
SM/J f 0.0636 0.134   8 0.0475 2.11 -0.149, 0.232 0.42
SM/J m 0.142 0.265   8 0.0938 1.87 -0.232, 0.55 0.82
SWR/J f 0.064 0.317   8 0.112 4.96 -0.376, 0.47 0.42
SWR/J m 0.0453 0.0985   9 0.0328 2.17 -0.051, 0.245 0.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f -0.145 0.0687 -0.0101 -0.2799
129S1/SvImJ m -0.1462 0.0687 -0.0113 -0.2812
A/J f 0.3799 0.0687 0.5148 0.2449
A/J m 0.4549 0.0687 0.5898 0.3199
AKR/J f 0.0145 0.0687 0.1494 -0.1204
AKR/J m -0.2166 0.0687 -0.0817 -0.3516
BALB/cByJ f -0.0406 0.0687 0.0943 -0.1756
BALB/cByJ m -0.1253 0.0687 0.0097 -0.2602
BALB/cJ f -0.0874 0.0614 0.0333 -0.2081
BALB/cJ m -0.0645 0.0614 0.0562 -0.1852
BTBR T+ Itpr3tf/J f 0.3762 0.0687 0.5112 0.2413
BTBR T+ Itpr3tf/J m 0.3897 0.0687 0.5247 0.2548
BUB/BnJ f 0.0286 0.0734 0.1728 -0.1157
BUB/BnJ m 0.0482 0.0687 0.1832 -0.0867
C3H/HeJ f -0.0601 0.0687 0.0748 -0.1951
C3H/HeJ m 0.0391 0.0687 0.1741 -0.0958
C57BL/10J f -0.0833 0.0687 0.0517 -0.2182
C57BL/10J m 0.0544 0.0734 0.1987 -0.0898
C57BL/6J f -0.1681 0.0734 -0.0239 -0.3124
C57BL/6J m -0.1848 0.0539 -0.079 -0.2907
C57BLKS/J f -0.1276 0.0585 -0.0126 -0.2427
C57BLKS/J m -0.0478 0.0687 0.0872 -0.1827
C57BR/cdJ f -0.1138 0.0793 0.042 -0.2697
C57BR/cdJ m -0.0571 0.0687 0.0778 -0.1921
C57L/J f -0.0813 0.0687 0.0537 -0.2162
C57L/J m -0.0884 0.0687 0.0466 -0.2233
CBA/J f -0.0781 0.0687 0.0568 -0.2131
CBA/J m -0.1311 0.0687 0.0038 -0.2661
CE/J f -0.0504 0.0687 0.0846 -0.1853
CE/J m 0.0171 0.0647 0.1443 -0.1101
DBA/1J f -0.0348 0.0614 0.0859 -0.1555
DBA/1J m 0.3245 0.0687 0.4594 0.1896
DBA/2J f 0.0557 0.0687 0.1907 -0.0792
DBA/2J m -0.0132 0.0614 0.1075 -0.1339
FVB/NJ f -0.0576 0.0687 0.0773 -0.1926
FVB/NJ m -0.1286 0.0734 0.0157 -0.2728
I/LnJ f 0.0657 0.0734 0.21 -0.0786
I/LnJ m 0.1368 0.0868 0.3075 -0.0339
KK/HlJ f -0.0929 0.0687 0.0421 -0.2278
KK/HlJ m -0.1353 0.0793 0.0205 -0.2912
LP/J f 0.0094 0.0687 0.1443 -0.1256
LP/J m -0.1887 0.0687 -0.0538 -0.3237
NOD/ShiLtJ f -0.3126 0.0687 -0.1777 -0.4476
NOD/ShiLtJ m -0.2215 0.0687 -0.0866 -0.3564
NON/ShiLtJ f 0.1759 0.0687 0.3108 0.0409
NON/ShiLtJ m 0.1141 0.0687 0.2491 -0.0208
NZW/LacJ f 0.1269 0.0687 0.2618 -0.0081
NZW/LacJ m -0.0476 0.0687 0.0873 -0.1826
PL/J f 0.2167 0.0687 0.3517 0.0818
PL/J m 0.0659 0.0687 0.2008 -0.0691
RIIIS/J f -0.0228 0.0687 0.1122 -0.1577
RIIIS/J m 0.0624 0.0687 0.1973 -0.0726
SJL/J f 0.0046 0.0687 0.1396 -0.1303
SJL/J m -0.0146 0.0687 0.1203 -0.1496
SM/J f 0.0636 0.0687 0.1986 -0.0713
SM/J m 0.1419 0.0687 0.2768 0.0069
SWR/J f 0.064 0.0687 0.1989 -0.0709
SWR/J m 0.0453 0.0647 0.1726 -0.0819


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both -0.1456 0.0485 -0.0502 -0.241
A/J both 0.4174 0.0485 0.5128 0.322
AKR/J both -0.1011 0.0485 -0.0056 -0.1965
BALB/cByJ both -0.0829 0.0485 0.0125 -0.1784
BALB/cJ both -0.076 0.0434 0.0094 -0.1613
BTBR T+ Itpr3tf/J both 0.383 0.0485 0.4784 0.2876
BUB/BnJ both 0.0384 0.0502 0.1372 -0.0604
C3H/HeJ both -0.0105 0.0485 0.0849 -0.1059
C57BL/10J both -0.0144 0.0502 0.0844 -0.1132
C57BL/6J both -0.1765 0.0455 -0.087 -0.266
C57BLKS/J both -0.0877 0.0451 0.001 -0.1764
C57BR/cdJ both -0.0855 0.0524 0.0176 -0.1885
C57L/J both -0.0848 0.0485 0.0106 -0.1802
CBA/J both -0.1046 0.0485 -0.0092 -0.2
CE/J both -0.0166 0.0472 0.0761 -0.1094
DBA/1J both 0.1448 0.0461 0.2354 0.0543
DBA/2J both 0.0213 0.0461 0.1118 -0.0693
FVB/NJ both -0.0931 0.0502 0.0057 -0.1919
I/LnJ both 0.1013 0.0568 0.213 -0.0105
KK/HlJ both -0.1141 0.0524 -0.011 -0.2172
LP/J both -0.0897 0.0485 0.0057 -0.1851
NOD/ShiLtJ both -0.2671 0.0485 -0.1716 -0.3625
NON/ShiLtJ both 0.145 0.0485 0.2404 0.0496
NZW/LacJ both 0.0396 0.0485 0.135 -0.0558
PL/J both 0.1413 0.0485 0.2367 0.0459
RIIIS/J both 0.0198 0.0485 0.1152 -0.0756
SJL/J both -0.005 0.0485 0.0904 -0.1004
SM/J both 0.1027 0.0485 0.1982 0.0073
SWR/J both 0.0547 0.0472 0.1474 -0.0381




  GWAS USING LINEAR MIXED MODELS