Project measure / variable:   Berndt2   tot_respi_saline

ID, description, units MPD:35128   tot_respi_saline   respiratory cycle   [s]  saline  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - respiratory cycle saline



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.297   s 0.286   s
Median of the strain means0.310   s 0.289   s
SD of the strain means± 0.0465 ± 0.0460
Coefficient of variation (CV)0.157 0.161
Min–max range of strain means0.197   –   0.373   s 0.210   –   0.379   s
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0161 0.0161 4.1642 0.0419
strain 28 0.8328 0.0297 7.7112 < 0.0001
sex:strain 28 0.1339 0.0048 1.2403 0.1887
Residuals 412 1.5892 0.0039


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.318 0.0884   8 0.0313 0.278 0.218, 0.473 0.46
129S1/SvImJ m 0.288 0.0672   8 0.0238 0.233 0.224, 0.394 0.05
A/J f 0.266 0.0358   8 0.0127 0.135 0.206, 0.312 -0.66
A/J m 0.248 0.027   8 0.00955 0.109 0.212, 0.284 -0.82
AKR/J f 0.314 0.115   8 0.0408 0.368 0.171, 0.546 0.37
AKR/J m 0.366 0.086   8 0.0304 0.235 0.242, 0.48 1.75
BALB/cByJ f 0.279 0.0421   8 0.0149 0.151 0.216, 0.346 -0.38
BALB/cByJ m 0.244 0.0352   8 0.0124 0.144 0.195, 0.291 -0.9
BALB/cJ f 0.243 0.0607   10 0.0192 0.249 0.146, 0.355 -1.15
BALB/cJ m 0.227 0.0463   10 0.0146 0.204 0.17, 0.337 -1.27
BTBR T+ Itpr3tf/J f 0.24 0.061   8 0.0216 0.254 0.18, 0.374 -1.22
BTBR T+ Itpr3tf/J m 0.21 0.0278   8 0.00984 0.132 0.179, 0.257 -1.64
BUB/BnJ f 0.326 0.0975   7 0.0369 0.3 0.191, 0.441 0.63
BUB/BnJ m 0.334 0.0732   8 0.0259 0.219 0.228, 0.431 1.05
C3H/HeJ f 0.333 0.073   8 0.0258 0.22 0.234, 0.456 0.78
C3H/HeJ m 0.364 0.07   8 0.0247 0.192 0.271, 0.449 1.7
C57BL/10J f 0.255 0.0313   8 0.0111 0.123 0.183, 0.286 -0.9
C57BL/10J m 0.219 0.015   7 0.00569 0.0686 0.199, 0.238 -1.45
C57BL/6J f 0.273 0.0478   7 0.0181 0.175 0.205, 0.339 -0.51
C57BL/6J m 0.262 0.0536   13 0.0149 0.205 0.193, 0.367 -0.51
C57BLKS/J f 0.276 0.0645   11 0.0194 0.234 0.197, 0.399 -0.44
C57BLKS/J m 0.284 0.0468   8 0.0165 0.165 0.225, 0.371 -0.03
C57BR/cdJ f 0.256 0.0696   6 0.0284 0.273 0.172, 0.358 -0.87
C57BR/cdJ m 0.235 0.0291   8 0.0103 0.124 0.205, 0.295 -1.1
C57L/J f 0.279 0.0483   8 0.0171 0.173 0.207, 0.34 -0.38
C57L/J m 0.3 0.0431   8 0.0153 0.144 0.231, 0.373 0.31
CBA/J f 0.327 0.058   8 0.0205 0.177 0.247, 0.407 0.65
CBA/J m 0.308 0.0645   8 0.0228 0.21 0.218, 0.388 0.49
CE/J f 0.243 0.0803   8 0.0284 0.33 0.193, 0.436 -1.15
CE/J m 0.259 0.0439   9 0.0146 0.17 0.206, 0.336 -0.58
DBA/1J f 0.314 0.0698   10 0.0221 0.222 0.206, 0.432 0.37
DBA/1J m 0.314 0.0793   8 0.0281 0.253 0.221, 0.428 0.62
DBA/2J f 0.264 0.0479   8 0.017 0.182 0.214, 0.34 -0.7
DBA/2J m 0.257 0.036   10 0.0114 0.14 0.205, 0.303 -0.62
FVB/NJ f 0.33 0.079   8 0.0279 0.24 0.209, 0.432 0.72
FVB/NJ m 0.29 0.0555   7 0.021 0.192 0.23, 0.383 0.1
I/LnJ f 0.334 0.0517   7 0.0195 0.154 0.255, 0.404 0.8
I/LnJ m 0.289 0.0357   5 0.0159 0.123 0.248, 0.329 0.07
KK/HlJ f 0.32 0.0619   8 0.0219 0.193 0.223, 0.427 0.5
KK/HlJ m 0.308 0.0382   6 0.0156 0.124 0.232, 0.339 0.49
LP/J f 0.363 0.11   8 0.0389 0.304 0.248, 0.597 1.43
LP/J m 0.301 0.06   8 0.0212 0.199 0.218, 0.381 0.33
NOD/ShiLtJ f 0.36 0.0791   8 0.028 0.22 0.235, 0.486 1.36
NOD/ShiLtJ m 0.322 0.0633   8 0.0224 0.196 0.221, 0.413 0.79
NON/ShiLtJ f 0.373 0.124   8 0.0438 0.332 0.254, 0.574 1.64
NON/ShiLtJ m 0.247 0.032   8 0.0113 0.13 0.19, 0.294 -0.84
NZW/LacJ f 0.366 0.0811   8 0.0287 0.221 0.258, 0.479 1.49
NZW/LacJ m 0.379 0.0434   8 0.0154 0.114 0.326, 0.424 2.03
PL/J f 0.31 0.0831   8 0.0294 0.268 0.187, 0.451 0.29
PL/J m 0.328 0.0754   8 0.0267 0.23 0.169, 0.402 0.92
RIIIS/J f 0.221 0.0392   8 0.0139 0.178 0.171, 0.267 -1.63
RIIIS/J m 0.244 0.0465   8 0.0164 0.191 0.213, 0.352 -0.9
SJL/J f 0.28 0.0346   8 0.0122 0.124 0.235, 0.356 -0.36
SJL/J m 0.289 0.0494   8 0.0175 0.171 0.234, 0.344 0.07
SM/J f 0.197 0.016   8 0.00565 0.0812 0.175, 0.22 -2.14
SM/J m 0.23 0.0291   8 0.0103 0.127 0.179, 0.267 -1.21
SWR/J f 0.343 0.0672   8 0.0238 0.196 0.247, 0.448 1.0
SWR/J m 0.336 0.0481   9 0.016 0.143 0.276, 0.426 1.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.3176 0.022 0.3608 0.2745
129S1/SvImJ m 0.2881 0.022 0.3313 0.245
A/J f 0.2656 0.022 0.3088 0.2225
A/J m 0.2478 0.022 0.2909 0.2046
AKR/J f 0.3142 0.022 0.3574 0.2711
AKR/J m 0.366 0.022 0.4092 0.3228
BALB/cByJ f 0.2789 0.022 0.322 0.2357
BALB/cByJ m 0.2442 0.022 0.2874 0.2011
BALB/cJ f 0.2434 0.0196 0.282 0.2048
BALB/cJ m 0.2271 0.0196 0.2657 0.1885
BTBR T+ Itpr3tf/J f 0.2399 0.022 0.283 0.1967
BTBR T+ Itpr3tf/J m 0.2104 0.022 0.2535 0.1672
BUB/BnJ f 0.3256 0.0235 0.3717 0.2794
BUB/BnJ m 0.3336 0.022 0.3768 0.2905
C3H/HeJ f 0.3326 0.022 0.3758 0.2895
C3H/HeJ m 0.3636 0.022 0.4068 0.3205
C57BL/10J f 0.2553 0.022 0.2984 0.2121
C57BL/10J m 0.2194 0.0235 0.2656 0.1733
C57BL/6J f 0.2729 0.0235 0.319 0.2267
C57BL/6J m 0.262 0.0172 0.2959 0.2281
C57BLKS/J f 0.2756 0.0187 0.3124 0.2388
C57BLKS/J m 0.2844 0.022 0.3275 0.2412
C57BR/cdJ f 0.2555 0.0254 0.3053 0.2057
C57BR/cdJ m 0.2354 0.022 0.2785 0.1922
C57L/J f 0.2794 0.022 0.3225 0.2362
C57L/J m 0.2998 0.022 0.3429 0.2566
CBA/J f 0.3271 0.022 0.3703 0.284
CBA/J m 0.3076 0.022 0.3508 0.2645
CE/J f 0.2429 0.022 0.286 0.1997
CE/J m 0.2587 0.0207 0.2994 0.218
DBA/1J f 0.3143 0.0196 0.3529 0.2757
DBA/1J m 0.314 0.022 0.3572 0.2708
DBA/2J f 0.2639 0.022 0.307 0.2207
DBA/2J m 0.2572 0.0196 0.2958 0.2186
FVB/NJ f 0.3296 0.022 0.3728 0.2865
FVB/NJ m 0.2897 0.0235 0.3359 0.2436
I/LnJ f 0.3344 0.0235 0.3806 0.2883
I/LnJ m 0.2888 0.0278 0.3434 0.2342
KK/HlJ f 0.32 0.022 0.3632 0.2768
KK/HlJ m 0.3078 0.0254 0.3577 0.258
LP/J f 0.3626 0.022 0.4058 0.3195
LP/J m 0.3013 0.022 0.3444 0.2581
NOD/ShiLtJ f 0.3599 0.022 0.403 0.3167
NOD/ShiLtJ m 0.3223 0.022 0.3654 0.2791
NON/ShiLtJ f 0.373 0.022 0.4162 0.3298
NON/ShiLtJ m 0.247 0.022 0.2902 0.2038
NZW/LacJ f 0.366 0.022 0.4092 0.3228
NZW/LacJ m 0.3793 0.022 0.4224 0.3361
PL/J f 0.3096 0.022 0.3528 0.2665
PL/J m 0.3275 0.022 0.3707 0.2843
RIIIS/J f 0.2206 0.022 0.2638 0.1775
RIIIS/J m 0.244 0.022 0.2872 0.2008
SJL/J f 0.2799 0.022 0.323 0.2367
SJL/J m 0.2889 0.022 0.332 0.2457
SM/J f 0.1969 0.022 0.24 0.1537
SM/J m 0.2298 0.022 0.2729 0.1866
SWR/J f 0.3429 0.022 0.386 0.2997
SWR/J m 0.3358 0.0207 0.3765 0.2951


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.3029 0.0155 0.3334 0.2724
A/J both 0.2567 0.0155 0.2872 0.2262
AKR/J both 0.3401 0.0155 0.3706 0.3096
BALB/cByJ both 0.2616 0.0155 0.2921 0.231
BALB/cJ both 0.2353 0.0139 0.2625 0.208
BTBR T+ Itpr3tf/J both 0.2251 0.0155 0.2556 0.1946
BUB/BnJ both 0.3296 0.0161 0.3612 0.298
C3H/HeJ both 0.3481 0.0155 0.3786 0.3176
C57BL/10J both 0.2373 0.0161 0.2689 0.2057
C57BL/6J both 0.2674 0.0146 0.296 0.2388
C57BLKS/J both 0.28 0.0144 0.3084 0.2516
C57BR/cdJ both 0.2454 0.0168 0.2784 0.2125
C57L/J both 0.2896 0.0155 0.3201 0.259
CBA/J both 0.3174 0.0155 0.3479 0.2869
CE/J both 0.2508 0.0151 0.2804 0.2211
DBA/1J both 0.3142 0.0147 0.3431 0.2852
DBA/2J both 0.2605 0.0147 0.2895 0.2316
FVB/NJ both 0.3097 0.0161 0.3413 0.2781
I/LnJ both 0.3116 0.0182 0.3474 0.2759
KK/HlJ both 0.3139 0.0168 0.3469 0.2809
LP/J both 0.3319 0.0155 0.3625 0.3014
NOD/ShiLtJ both 0.3411 0.0155 0.3716 0.3105
NON/ShiLtJ both 0.31 0.0155 0.3405 0.2795
NZW/LacJ both 0.3726 0.0155 0.4031 0.3421
PL/J both 0.3186 0.0155 0.3491 0.288
RIIIS/J both 0.2323 0.0155 0.2628 0.2018
SJL/J both 0.2844 0.0155 0.3149 0.2539
SM/J both 0.2133 0.0155 0.2438 0.1828
SWR/J both 0.3393 0.0151 0.369 0.3097




  GWAS USING LINEAR MIXED MODELS