Project measure / variable:   Berndt2   tot_respi_mch10

ID, description, units MPD:35130   tot_respi_mch10   respiratory cycle   [s]  10 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - respiratory cycle 10 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.302   s 0.286   s
Median of the strain means0.286   s 0.277   s
SD of the strain means± 0.0871 ± 0.0612
Coefficient of variation (CV)0.289 0.214
Min–max range of strain means0.179   –   0.639   s 0.181   –   0.446   s
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0261 0.0261 6.323 0.0123
strain 28 2.3577 0.0842 20.4117 < 0.0001
sex:strain 28 0.2219 0.0079 1.9211 0.0037
Residuals 412 1.6996 0.0041


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.341 0.0741   8 0.0262 0.218 0.25, 0.45 0.45
129S1/SvImJ m 0.296 0.0561   8 0.0198 0.189 0.218, 0.37 0.17
A/J f 0.272 0.0616   8 0.0218 0.227 0.218, 0.409 -0.34
A/J m 0.277 0.0733   8 0.0259 0.264 0.213, 0.434 -0.14
AKR/J f 0.286 0.0871   8 0.0308 0.305 0.166, 0.437 -0.18
AKR/J m 0.285 0.0478   8 0.0169 0.168 0.237, 0.351 -0.01
BALB/cByJ f 0.224 0.0178   8 0.00628 0.0792 0.197, 0.246 -0.89
BALB/cByJ m 0.237 0.0682   8 0.0241 0.287 0.189, 0.401 -0.8
BALB/cJ f 0.212 0.0333   10 0.0105 0.157 0.173, 0.266 -1.03
BALB/cJ m 0.189 0.0174   10 0.00549 0.092 0.165, 0.219 -1.58
BTBR T+ Itpr3tf/J f 0.241 0.0505   8 0.0178 0.209 0.178, 0.341 -0.7
BTBR T+ Itpr3tf/J m 0.256 0.0661   8 0.0234 0.259 0.199, 0.403 -0.49
BUB/BnJ f 0.338 0.0495   7 0.0187 0.146 0.295, 0.432 0.42
BUB/BnJ m 0.286 0.0503   8 0.0178 0.176 0.233, 0.373 0.0
C3H/HeJ f 0.398 0.0836   8 0.0295 0.21 0.324, 0.57 1.1
C3H/HeJ m 0.399 0.12   8 0.0426 0.302 0.241, 0.65 1.85
C57BL/10J f 0.252 0.0264   8 0.00934 0.105 0.213, 0.291 -0.57
C57BL/10J m 0.205 0.02   7 0.00758 0.0977 0.178, 0.239 -1.32
C57BL/6J f 0.286 0.0292   7 0.011 0.102 0.258, 0.34 -0.18
C57BL/6J m 0.273 0.0462   13 0.0128 0.169 0.194, 0.352 -0.21
C57BLKS/J f 0.239 0.0208   11 0.00627 0.087 0.2, 0.263 -0.72
C57BLKS/J m 0.228 0.0682   8 0.0241 0.299 0.162, 0.356 -0.94
C57BR/cdJ f 0.259 0.0561   6 0.0229 0.217 0.194, 0.341 -0.49
C57BR/cdJ m 0.242 0.0371   8 0.0131 0.153 0.185, 0.307 -0.72
C57L/J f 0.261 0.0376   8 0.0133 0.144 0.216, 0.329 -0.47
C57L/J m 0.227 0.0334   8 0.0118 0.147 0.188, 0.282 -0.96
CBA/J f 0.252 0.0205   8 0.00724 0.0812 0.229, 0.281 -0.57
CBA/J m 0.267 0.0247   8 0.00872 0.0923 0.233, 0.315 -0.31
CE/J f 0.319 0.0785   8 0.0278 0.246 0.248, 0.469 0.2
CE/J m 0.315 0.0867   9 0.0289 0.276 0.219, 0.452 0.48
DBA/1J f 0.265 0.04   10 0.0127 0.151 0.203, 0.342 -0.42
DBA/1J m 0.271 0.0477   8 0.0169 0.176 0.201, 0.343 -0.24
DBA/2J f 0.243 0.0365   8 0.0129 0.15 0.207, 0.32 -0.67
DBA/2J m 0.294 0.0412   10 0.013 0.14 0.236, 0.36 0.13
FVB/NJ f 0.289 0.0427   8 0.0151 0.148 0.249, 0.375 -0.15
FVB/NJ m 0.244 0.0375   7 0.0142 0.153 0.198, 0.314 -0.68
I/LnJ f 0.313 0.0879   7 0.0332 0.28 0.235, 0.477 0.13
I/LnJ m 0.313 0.0627   5 0.0281 0.201 0.243, 0.404 0.44
KK/HlJ f 0.326 0.0617   8 0.0218 0.19 0.234, 0.422 0.28
KK/HlJ m 0.302 0.082   6 0.0335 0.272 0.191, 0.443 0.27
LP/J f 0.357 0.0712   8 0.0252 0.199 0.267, 0.451 0.63
LP/J m 0.319 0.0557   8 0.0197 0.175 0.197, 0.376 0.54
NOD/ShiLtJ f 0.282 0.0455   8 0.0161 0.161 0.222, 0.352 -0.23
NOD/ShiLtJ m 0.249 0.0518   8 0.0183 0.208 0.186, 0.335 -0.6
NON/ShiLtJ f 0.639 0.132   8 0.0466 0.206 0.489, 0.829 3.87
NON/ShiLtJ m 0.446 0.152   8 0.0536 0.34 0.242, 0.7 2.62
NZW/LacJ f 0.309 0.0712   8 0.0252 0.23 0.235, 0.467 0.08
NZW/LacJ m 0.334 0.0724   8 0.0256 0.217 0.234, 0.434 0.79
PL/J f 0.452 0.132   8 0.0468 0.293 0.302, 0.669 1.72
PL/J m 0.381 0.0759   8 0.0268 0.199 0.261, 0.512 1.56
RIIIS/J f 0.237 0.0252   8 0.0089 0.106 0.189, 0.27 -0.74
RIIIS/J m 0.27 0.0494   8 0.0175 0.183 0.198, 0.338 -0.26
SJL/J f 0.318 0.0589   8 0.0208 0.185 0.232, 0.398 0.19
SJL/J m 0.341 0.0677   8 0.0239 0.199 0.246, 0.418 0.9
SM/J f 0.179 0.0201   8 0.00712 0.112 0.158, 0.209 -1.41
SM/J m 0.181 0.0179   8 0.00633 0.0989 0.155, 0.203 -1.71
SWR/J f 0.362 0.092   8 0.0325 0.254 0.254, 0.49 0.69
SWR/J m 0.361 0.0791   9 0.0264 0.219 0.234, 0.49 1.23


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.3406 0.0227 0.3853 0.296
129S1/SvImJ m 0.2961 0.0227 0.3408 0.2515
A/J f 0.2719 0.0227 0.3165 0.2272
A/J m 0.2771 0.0227 0.3218 0.2325
AKR/J f 0.2856 0.0227 0.3303 0.241
AKR/J m 0.285 0.0227 0.3296 0.2404
BALB/cByJ f 0.2241 0.0227 0.2688 0.1795
BALB/cByJ m 0.2374 0.0227 0.282 0.1927
BALB/cJ f 0.2116 0.0203 0.2515 0.1717
BALB/cJ m 0.1887 0.0203 0.2286 0.1488
BTBR T+ Itpr3tf/J f 0.241 0.0227 0.2856 0.1964
BTBR T+ Itpr3tf/J m 0.2555 0.0227 0.3001 0.2109
BUB/BnJ f 0.3384 0.0243 0.3861 0.2907
BUB/BnJ m 0.2858 0.0227 0.3304 0.2411
C3H/HeJ f 0.3976 0.0227 0.4423 0.353
C3H/HeJ m 0.399 0.0227 0.4436 0.3544
C57BL/10J f 0.2524 0.0227 0.297 0.2077
C57BL/10J m 0.2051 0.0243 0.2529 0.1574
C57BL/6J f 0.2856 0.0243 0.3333 0.2379
C57BL/6J m 0.2734 0.0178 0.3084 0.2384
C57BLKS/J f 0.2388 0.0194 0.2769 0.2008
C57BLKS/J m 0.2281 0.0227 0.2728 0.1835
C57BR/cdJ f 0.259 0.0262 0.3105 0.2075
C57BR/cdJ m 0.2419 0.0227 0.2865 0.1972
C57L/J f 0.2611 0.0227 0.3058 0.2165
C57L/J m 0.2274 0.0227 0.272 0.1827
CBA/J f 0.252 0.0227 0.2966 0.2074
CBA/J m 0.2671 0.0227 0.3118 0.2225
CE/J f 0.319 0.0227 0.3636 0.2744
CE/J m 0.3146 0.0214 0.3566 0.2725
DBA/1J f 0.2647 0.0203 0.3046 0.2248
DBA/1J m 0.2712 0.0227 0.3159 0.2266
DBA/2J f 0.2431 0.0227 0.2878 0.1985
DBA/2J m 0.2939 0.0203 0.3338 0.254
FVB/NJ f 0.2892 0.0227 0.3339 0.2446
FVB/NJ m 0.2444 0.0243 0.2921 0.1967
I/LnJ f 0.3134 0.0243 0.3611 0.2657
I/LnJ m 0.3128 0.0287 0.3693 0.2563
KK/HlJ f 0.3256 0.0227 0.3703 0.281
KK/HlJ m 0.302 0.0262 0.3535 0.2505
LP/J f 0.3573 0.0227 0.4019 0.3126
LP/J m 0.3188 0.0227 0.3634 0.2741
NOD/ShiLtJ f 0.2825 0.0227 0.3271 0.2379
NOD/ShiLtJ m 0.2488 0.0227 0.2934 0.2041
NON/ShiLtJ f 0.6395 0.0227 0.6841 0.5949
NON/ShiLtJ m 0.4455 0.0227 0.4901 0.4009
NZW/LacJ f 0.3091 0.0227 0.3538 0.2645
NZW/LacJ m 0.3338 0.0227 0.3784 0.2891
PL/J f 0.4521 0.0227 0.4968 0.4075
PL/J m 0.3809 0.0227 0.4255 0.3362
RIIIS/J f 0.2367 0.0227 0.2814 0.1921
RIIIS/J m 0.2703 0.0227 0.3149 0.2256
SJL/J f 0.3184 0.0227 0.363 0.2737
SJL/J m 0.3406 0.0227 0.3853 0.296
SM/J f 0.1791 0.0227 0.2238 0.1345
SM/J m 0.181 0.0227 0.2256 0.1364
SWR/J f 0.3624 0.0227 0.407 0.3177
SWR/J m 0.3612 0.0214 0.4033 0.3191


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.3184 0.0161 0.3499 0.2868
A/J both 0.2745 0.0161 0.3061 0.2429
AKR/J both 0.2853 0.0161 0.3169 0.2537
BALB/cByJ both 0.2307 0.0161 0.2623 0.1992
BALB/cJ both 0.2002 0.0144 0.2284 0.1719
BTBR T+ Itpr3tf/J both 0.2482 0.0161 0.2798 0.2167
BUB/BnJ both 0.3121 0.0166 0.3448 0.2794
C3H/HeJ both 0.3983 0.0161 0.4299 0.3667
C57BL/10J both 0.2288 0.0166 0.2614 0.1961
C57BL/6J both 0.2795 0.0151 0.3091 0.2499
C57BLKS/J both 0.2335 0.0149 0.2628 0.2041
C57BR/cdJ both 0.2504 0.0173 0.2845 0.2163
C57L/J both 0.2443 0.0161 0.2758 0.2127
CBA/J both 0.2596 0.0161 0.2911 0.228
CE/J both 0.3168 0.0156 0.3475 0.2861
DBA/1J both 0.268 0.0152 0.2979 0.238
DBA/2J both 0.2685 0.0152 0.2985 0.2386
FVB/NJ both 0.2668 0.0166 0.2995 0.2342
I/LnJ both 0.3131 0.0188 0.3501 0.2762
KK/HlJ both 0.3138 0.0173 0.3479 0.2797
LP/J both 0.338 0.0161 0.3696 0.3064
NOD/ShiLtJ both 0.2656 0.0161 0.2972 0.2341
NON/ShiLtJ both 0.5425 0.0161 0.5741 0.5109
NZW/LacJ both 0.3214 0.0161 0.353 0.2899
PL/J both 0.4165 0.0161 0.4481 0.3849
RIIIS/J both 0.2535 0.0161 0.2851 0.2219
SJL/J both 0.3295 0.0161 0.3611 0.2979
SM/J both 0.1801 0.0161 0.2116 0.1485
SWR/J both 0.3618 0.0156 0.3925 0.3311




  GWAS USING LINEAR MIXED MODELS