Project measure / variable:   Berndt2   tot_respi_mch5

ID, description, units MPD:35129   tot_respi_mch5   respiratory cycle   [s]  5 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - respiratory cycle 5 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.292   s 0.291   s
Median of the strain means0.289   s 0.282   s
SD of the strain means± 0.0512 ± 0.0521
Coefficient of variation (CV)0.175 0.179
Min–max range of strain means0.205   –   0.404   s 0.183   –   0.394   s
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0004 0.0004 0.0998 0.7522
strain 28 1.0451 0.0373 8.323 < 0.0001
sex:strain 28 0.1517 0.0054 1.2083 0.2168
Residuals 412 1.8477 0.0045


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.364 0.0876   8 0.031 0.241 0.225, 0.466 1.41
129S1/SvImJ m 0.357 0.106   8 0.0374 0.296 0.212, 0.476 1.27
A/J f 0.247 0.0364   8 0.0129 0.148 0.211, 0.31 -0.88
A/J m 0.254 0.0262   8 0.00927 0.103 0.215, 0.291 -0.7
AKR/J f 0.282 0.0914   8 0.0323 0.324 0.158, 0.475 -0.2
AKR/J m 0.347 0.0841   8 0.0297 0.242 0.236, 0.525 1.08
BALB/cByJ f 0.256 0.0289   8 0.0102 0.113 0.224, 0.301 -0.7
BALB/cByJ m 0.25 0.0325   8 0.0115 0.13 0.213, 0.309 -0.78
BALB/cJ f 0.232 0.0271   10 0.00857 0.117 0.185, 0.278 -1.17
BALB/cJ m 0.215 0.0124   10 0.00392 0.0577 0.19, 0.234 -1.45
BTBR T+ Itpr3tf/J f 0.221 0.0541   8 0.0191 0.245 0.164, 0.341 -1.39
BTBR T+ Itpr3tf/J m 0.183 0.0102   8 0.00362 0.0561 0.172, 0.199 -2.06
BUB/BnJ f 0.309 0.0679   7 0.0257 0.22 0.246, 0.402 0.33
BUB/BnJ m 0.394 0.115   8 0.0405 0.291 0.237, 0.581 1.98
C3H/HeJ f 0.404 0.15   8 0.0529 0.37 0.272, 0.696 2.19
C3H/HeJ m 0.359 0.0943   8 0.0333 0.263 0.259, 0.512 1.31
C57BL/10J f 0.243 0.0263   8 0.00929 0.108 0.209, 0.285 -0.96
C57BL/10J m 0.23 0.0214   7 0.00809 0.093 0.201, 0.263 -1.16
C57BL/6J f 0.289 0.0279   7 0.0105 0.0965 0.243, 0.324 -0.06
C57BL/6J m 0.283 0.0471   13 0.0131 0.166 0.24, 0.367 -0.15
C57BLKS/J f 0.277 0.0469   11 0.0141 0.169 0.235, 0.378 -0.29
C57BLKS/J m 0.269 0.0441   8 0.0156 0.164 0.213, 0.349 -0.41
C57BR/cdJ f 0.238 0.027   6 0.011 0.113 0.218, 0.29 -1.05
C57BR/cdJ m 0.255 0.0451   8 0.016 0.177 0.201, 0.312 -0.68
C57L/J f 0.25 0.0317   8 0.0112 0.127 0.196, 0.304 -0.82
C57L/J m 0.272 0.0335   8 0.0119 0.123 0.23, 0.326 -0.36
CBA/J f 0.268 0.0217   8 0.00768 0.0809 0.238, 0.305 -0.47
CBA/J m 0.28 0.0373   8 0.0132 0.133 0.226, 0.344 -0.2
CE/J f 0.29 0.0773   8 0.0273 0.266 0.215, 0.468 -0.04
CE/J m 0.301 0.0964   9 0.0321 0.321 0.186, 0.522 0.2
DBA/1J f 0.308 0.0438   10 0.0138 0.142 0.224, 0.376 0.31
DBA/1J m 0.25 0.0524   8 0.0185 0.21 0.203, 0.319 -0.78
DBA/2J f 0.245 0.0492   8 0.0174 0.201 0.212, 0.364 -0.92
DBA/2J m 0.282 0.0691   10 0.0219 0.245 0.222, 0.385 -0.16
FVB/NJ f 0.31 0.0512   8 0.0181 0.165 0.246, 0.393 0.35
FVB/NJ m 0.267 0.0506   7 0.0191 0.189 0.197, 0.334 -0.45
I/LnJ f 0.306 0.0817   7 0.0309 0.267 0.213, 0.463 0.27
I/LnJ m 0.269 0.0229   5 0.0102 0.0852 0.242, 0.303 -0.41
KK/HlJ f 0.324 0.0399   8 0.0141 0.123 0.266, 0.394 0.62
KK/HlJ m 0.365 0.0703   6 0.0287 0.192 0.273, 0.473 1.43
LP/J f 0.384 0.157   8 0.0553 0.408 0.239, 0.704 1.8
LP/J m 0.35 0.109   8 0.0384 0.31 0.246, 0.551 1.14
NOD/ShiLtJ f 0.358 0.0844   8 0.0298 0.236 0.202, 0.444 1.29
NOD/ShiLtJ m 0.304 0.0879   8 0.0311 0.289 0.177, 0.419 0.26
NON/ShiLtJ f 0.366 0.135   8 0.0476 0.368 0.232, 0.673 1.44
NON/ShiLtJ m 0.32 0.069   8 0.0244 0.216 0.246, 0.425 0.56
NZW/LacJ f 0.272 0.0351   8 0.0124 0.129 0.243, 0.34 -0.39
NZW/LacJ m 0.323 0.0471   8 0.0166 0.146 0.262, 0.405 0.62
PL/J f 0.3 0.0418   8 0.0148 0.139 0.238, 0.346 0.16
PL/J m 0.353 0.0837   8 0.0296 0.237 0.224, 0.437 1.2
RIIIS/J f 0.254 0.0286   8 0.0101 0.113 0.224, 0.314 -0.74
RIIIS/J m 0.25 0.0503   8 0.0178 0.201 0.201, 0.356 -0.78
SJL/J f 0.32 0.0741   8 0.0262 0.232 0.227, 0.456 0.55
SJL/J m 0.303 0.0558   8 0.0197 0.184 0.228, 0.386 0.24
SM/J f 0.205 0.0262   8 0.00928 0.128 0.178, 0.259 -1.7
SM/J m 0.214 0.0396   8 0.014 0.185 0.167, 0.277 -1.47
SWR/J f 0.346 0.0804   8 0.0284 0.232 0.252, 0.428 1.05
SWR/J m 0.328 0.0497   9 0.0166 0.152 0.263, 0.426 0.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.3643 0.0237 0.4108 0.3177
129S1/SvImJ m 0.3567 0.0237 0.4033 0.3102
A/J f 0.2465 0.0237 0.293 0.2
A/J m 0.2542 0.0237 0.3008 0.2077
AKR/J f 0.2824 0.0237 0.3289 0.2358
AKR/J m 0.347 0.0237 0.3935 0.3005
BALB/cByJ f 0.2564 0.0237 0.3029 0.2098
BALB/cByJ m 0.2504 0.0237 0.2969 0.2038
BALB/cJ f 0.2321 0.0212 0.2737 0.1905
BALB/cJ m 0.2146 0.0212 0.2562 0.173
BTBR T+ Itpr3tf/J f 0.221 0.0237 0.2675 0.1745
BTBR T+ Itpr3tf/J m 0.1826 0.0237 0.2292 0.1361
BUB/BnJ f 0.3091 0.0253 0.3589 0.2594
BUB/BnJ m 0.3936 0.0237 0.4402 0.3471
C3H/HeJ f 0.4044 0.0237 0.4509 0.3578
C3H/HeJ m 0.3587 0.0237 0.4053 0.3122
C57BL/10J f 0.243 0.0237 0.2895 0.1965
C57BL/10J m 0.2303 0.0253 0.28 0.1805
C57BL/6J f 0.2889 0.0253 0.3386 0.2391
C57BL/6J m 0.2834 0.0186 0.3199 0.2469
C57BLKS/J f 0.2773 0.0202 0.317 0.2376
C57BLKS/J m 0.2694 0.0237 0.3159 0.2228
C57BR/cdJ f 0.2383 0.0273 0.2921 0.1846
C57BR/cdJ m 0.2545 0.0237 0.301 0.208
C57L/J f 0.2501 0.0237 0.2967 0.2036
C57L/J m 0.2722 0.0237 0.3188 0.2257
CBA/J f 0.2684 0.0237 0.3149 0.2218
CBA/J m 0.2796 0.0237 0.3262 0.2331
CE/J f 0.2901 0.0237 0.3367 0.2436
CE/J m 0.3007 0.0223 0.3445 0.2568
DBA/1J f 0.3081 0.0212 0.3497 0.2665
DBA/1J m 0.25 0.0237 0.2965 0.2035
DBA/2J f 0.2448 0.0237 0.2913 0.1982
DBA/2J m 0.2821 0.0212 0.3237 0.2405
FVB/NJ f 0.3098 0.0237 0.3563 0.2632
FVB/NJ m 0.267 0.0253 0.3168 0.2172
I/LnJ f 0.3064 0.0253 0.3562 0.2567
I/LnJ m 0.2686 0.0299 0.3275 0.2097
KK/HlJ f 0.3244 0.0237 0.3709 0.2778
KK/HlJ m 0.3655 0.0273 0.4192 0.3118
LP/J f 0.3839 0.0237 0.4304 0.3373
LP/J m 0.3505 0.0237 0.397 0.304
NOD/ShiLtJ f 0.3582 0.0237 0.4048 0.3117
NOD/ShiLtJ m 0.3042 0.0237 0.3508 0.2577
NON/ShiLtJ f 0.366 0.0237 0.4125 0.3195
NON/ShiLtJ m 0.3196 0.0237 0.3662 0.2731
NZW/LacJ f 0.2718 0.0237 0.3183 0.2252
NZW/LacJ m 0.323 0.0237 0.3695 0.2765
PL/J f 0.3 0.0237 0.3465 0.2535
PL/J m 0.3534 0.0237 0.3999 0.3068
RIIIS/J f 0.2538 0.0237 0.3003 0.2072
RIIIS/J m 0.2502 0.0237 0.2968 0.2037
SJL/J f 0.3198 0.0237 0.3663 0.2732
SJL/J m 0.3027 0.0237 0.3493 0.2562
SM/J f 0.2053 0.0237 0.2518 0.1587
SM/J m 0.2137 0.0237 0.2603 0.1672
SWR/J f 0.3461 0.0237 0.3927 0.2996
SWR/J m 0.3278 0.0223 0.3717 0.2839


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.3605 0.0167 0.3934 0.3276
A/J both 0.2504 0.0167 0.2833 0.2175
AKR/J both 0.3147 0.0167 0.3476 0.2818
BALB/cByJ both 0.2534 0.0167 0.2863 0.2205
BALB/cJ both 0.2233 0.015 0.2528 0.1939
BTBR T+ Itpr3tf/J both 0.2018 0.0167 0.2347 0.1689
BUB/BnJ both 0.3514 0.0173 0.3854 0.3173
C3H/HeJ both 0.3816 0.0167 0.4145 0.3487
C57BL/10J both 0.2366 0.0173 0.2707 0.2026
C57BL/6J both 0.2861 0.0157 0.317 0.2553
C57BLKS/J both 0.2733 0.0156 0.3039 0.2427
C57BR/cdJ both 0.2464 0.0181 0.282 0.2109
C57L/J both 0.2612 0.0167 0.2941 0.2283
CBA/J both 0.274 0.0167 0.3069 0.2411
CE/J both 0.2954 0.0163 0.3274 0.2634
DBA/1J both 0.279 0.0159 0.3103 0.2478
DBA/2J both 0.2634 0.0159 0.2946 0.2322
FVB/NJ both 0.2884 0.0173 0.3224 0.2543
I/LnJ both 0.2875 0.0196 0.3261 0.249
KK/HlJ both 0.3449 0.0181 0.3805 0.3094
LP/J both 0.3672 0.0167 0.4001 0.3343
NOD/ShiLtJ both 0.3312 0.0167 0.3642 0.2983
NON/ShiLtJ both 0.3428 0.0167 0.3757 0.3099
NZW/LacJ both 0.2974 0.0167 0.3303 0.2645
PL/J both 0.3267 0.0167 0.3596 0.2938
RIIIS/J both 0.252 0.0167 0.2849 0.2191
SJL/J both 0.3113 0.0167 0.3442 0.2783
SM/J both 0.2095 0.0167 0.2424 0.1766
SWR/J both 0.337 0.0163 0.3689 0.305




  GWAS USING LINEAR MIXED MODELS