MPD: Data set: Schalkwyk1

Lad HV, Liu L, Paya-Cano JL, Parsons MJ, Kember R, Fernandes C, Schalkwyk LC. Behavioural battery testing: evaluation and behavioural outcomes in 8 inbred mouse strains. Physiol Behav. 2010 Mar 3;99(3):301-16. Epub 2009 Dec 2. PubMed 19931548

Procedures conducted:

• Morris water maze		Spatial learning and memory. Multiple trials.
• light-dark box		Anxiety-related behavior.
• open field test		Locomotor activity and exploratory behavior. 5 min test.
• elevated plus maze		Anxiety-related and exploratory behavior. 5 min test.
• puzzle box		Learning and memory.
• tail suspension test		Duration of immobility. Two trials.

Notes
Individual animal ids not supplied by investigator; unique ids were generated by MPD staff.

Schalkwyk1 downloads
• Download Schalkwyk1 project data set animal data, as uploaded
• Download Schalkwyk1 animal data matrix with factor-related expansion applied as necessary
• Download Schalkwyk1 strain means, SD, N, etc. one row per strain/sex/measure

Ontology terms mapped to Schalkwyk1 measures:

MP:0001362 abnormal anxiety-related response
MP:0001392 abnormal locomotor behavior
MP:0002063 abnormal learning/memory/conditioning
MP:0002803 abnormal operant conditioning behavior
MP:0003107 abnormal response to novelty
MP:0003360 abnormal depression-related behavior
MP:0008414 abnormal spatial reference memory
MP:0011832 abnormal visual acuity
MP:0013189 abnormal exploration in a new environment
VT:0001392 locomotor behavior trait
VT:0002001 visual acuity trait
VT:0002063 learning/memory/conditioning trait
VT:0010471 exploratory behavior trait
VT:0010531 operant conditioning behavior trait
VT:0010709 behavioral response to novel object trait
VT:0010716 anxiety-related behavior trait
VT:0010727 spatial reference memory trait
VT:0015015 depression-related behavior trait

Investigators	Leonard C Schalkwyk King's College London, Institute of Psychiatry, London UK Cathy Fernandes King's College London, Institute of Psychiatry, London UK Rachel Kember King's College London, Institute of Psychiatry, London UK Heena V Lad King's College London, Institute of Psychiatry, London UK Lin Liu King's College London, Institute of Psychiatry, London UK Michael J Parsons King's College London, Institute of Psychiatry, London UK
Contact	Leonard C Schalkwyk Leonard.Schalkwyk@kcl.ac.uk Lab web site
Acknowledgements	Funding provided by the Medical Research Council (G0000170)
Project type	Phenotype strain survey data set
MPD identifiers	Schalkwyk1 MPD:345
Data changelog	No updates/corrections. Initial release date: 12/2010.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)
Schalkwyk1:1	Schalkwyk1	open field test	(none)	locomotor activity, center, 5 min test [cm] act_center_OFT 34501	inbred	8	m	9-11wks	N=11

Schalkwyk1:2	Schalkwyk1	open field test	(none)	locomotor activity, periphery, 5 min test [cm] act_periph_OFT 34502	inbred	8	m	9-11wks	N=11

Schalkwyk1:3	Schalkwyk1	open field test	(none)	rearing frequency with novel object, 5 min test [%] pct_rear_OFTobj 34503	inbred	8	m	9-11wks	N=11

Schalkwyk1:4	Schalkwyk1	open field test	(none)	latency to enter center, 5 min test [s] laten_center_OFT 34504	inbred	8	m	9-11wks	N=11

Schalkwyk1:5	Schalkwyk1	open field test	(none)	duration in center, 5 min test [s] dur_center_OFT 34505	inbred	8	m	9-11wks	N=11

Schalkwyk1:6	Schalkwyk1	open field test	(none)	latency to explore novel object, 5 min test [s] laten_explore_OFTobj 34506	inbred	8	m	9-11wks	N=11

Schalkwyk1:7	Schalkwyk1	open field test	(none)	duration exploring novel object, 5 min test [s] dur_explore_OFTobj 34507	inbred	8	m	9-11wks	N=11

Schalkwyk1:8	Schalkwyk1	open field test	(none)	frequency exploring novel object, 5 min test [%] pct_explore_OFTobj 34508	inbred	8	m	9-11wks	N=11

Schalkwyk1:9	Schalkwyk1	elevated plus maze	(none)	number of open arms entries, 5 min test [n] entry_open_EPM 34509	inbred	8	m	9-11wks	N=11

Schalkwyk1:10	Schalkwyk1	elevated plus maze	(none)	latency to enter open arms, 5 min test [s] laten_open_EPM 34510	inbred	8	m	9-11wks	N=11

Schalkwyk1:11	Schalkwyk1	elevated plus maze	(none)	duration in open arms, 5 min test [s] dur_open_EPM 34511	inbred	8	m	9-11wks	N=11

Schalkwyk1:12	Schalkwyk1	elevated plus maze	(none)	duration in center, 5 min test [s] dur_center_EPM 34512	inbred	8	m	9-11wks	N=11

Schalkwyk1:13	Schalkwyk1	elevated plus maze	(none)	number of closed arms entries, 5 min test [n] entry_close_EPM 34513	inbred	8	m	9-11wks	N=11

Schalkwyk1:14	Schalkwyk1	elevated plus maze	(none)	duration in closed arms, 5 min test [s] dur_close_EPM 34514	inbred	8	m	9-11wks	N=11

Schalkwyk1:15	Schalkwyk1	light-dark box	(none)	latency to enter light chamber, 5 min test [s] laten_light_LD 34515	inbred	8	m	9-11wks	N=11

Schalkwyk1:16	Schalkwyk1	light-dark box	(none)	duration in light chamber, 5 min test [s] dur_light_LD 34516	inbred	8	m	9-11wks	N=11

Schalkwyk1:17	Schalkwyk1	light-dark box	(none)	number of light-dark transitions, 5 min test [n] transitions_LD 34517	inbred	8	m	9-11wks	N=11

Schalkwyk1:18	Schalkwyk1	puzzle box	(none)	latency to reach goal during training, 3 min test [s] laten_goal_PBtrain 34518	inbred	8	m	9-11wks	N=11

Schalkwyk1:19	Schalkwyk1	puzzle box	(none)	latency to reach goal during burrowing task, 3 min test [s] laten_goal_PBbur 34519	inbred	8	m	9-11wks	N=11

Schalkwyk1:20	Schalkwyk1	puzzle box	(none)	latency to reach goal during plug task, 3 min test [s] laten_goal_PBplug 34520	inbred	8	m	9-11wks	N=11

Schalkwyk1:21	Schalkwyk1	Morris water maze	(none)	latency to reach visible platform, 1 min test [s] laten_visplat_MWM 34521	inbred	8	m	9-11wks	N=11

Schalkwyk1:22	Schalkwyk1	Morris water maze	(none)	latency to reach hidden platform, 1 min test [s] laten_hidplat 34522 trial: 1 2 3 4 5 6 7	inbred	8	m	9-11wks	N=11

Schalkwyk1:29	Schalkwyk1	Morris water maze	(none)	latency to reach reversed platform, 1 min test [s] laten_revplat 34529 trial 1 trial 2	inbred	8	m	9-11wks	N=11

Schalkwyk1:31	Schalkwyk1	tail suspension test	(none)	TST duration of immobility, 5 min test [s] dur_immobil 34531 trial 1 trial 2	inbred	8	m	9-11wks	N=10

Schalkwyk1: Battery of behavioral testing in males of 8 inbred mouse strains (2010)

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