HMDPpheno4: Fear conditioning in males of 94 strains of mice in the Hybrid Mouse Diversity Panel (HMDP) (2011)

Park CC, Gale GD, de Jong S, Ghazalpour A, Bennett BJ, Farber CR, Langfelder P, Lin A, Khan AH, Eskin E, Horvath S, Lusis AJ, Ophoff RA, Smith DJ. Gene networks associated with conditional fear in mice identified using a systems genetics approach. BMC Syst Biol. 2011 Mar 16;5:43. doi: 10.1186/1752-0509-5-43.   PubMed 21410935     FullText


         
An associated gene expression study is available in GEO: GSE26500

Procedures conducted:
• fear conditioning test  Contextual fear, cued fear.

HMDPpheno4 downloads
• Download HMDPpheno4 project data set     animal data, as uploaded
• Download HMDPpheno4 animal data matrix     with factor-related expansion applied as necessary
• Download HMDPpheno4 strain means, SD, N, etc.     one row per strain/sex/measure
• HMDPpheno4 supplementary data
Investigators Christopher C Park       University of California, Los Angeles,  Los Angeles, CA
Greg D Gale       University of California, Los Angeles,  Los Angeles, CA
Aldons J Lusis       University of California, Los Angeles,  Los Angeles, CA
Desmond J Smith       University of California, Los Angeles,  Los Angeles, CA
Participants Khan AH, de Jong S, Ghazalpour A, Bennett BJ, Farber CR, Langfelder P, Lin A, Eskin E, Horvath S, Ophoff RA
ContactDesmond J Smith     dsmith@mednet.ucla.edu     Lab web site
Affiliated CenterHybrid Mouse Diversity Panel Group (HMDP)
AcknowledgementsFunding provided by NIH MH071779
Project type Phenotype strain survey data set
MPD identifiersHMDPpheno4     MPD:468
Data changelog No updates/corrections.       Initial release date: 04/2013.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
Mice: HMDP   94 strains   ♂   age 10wks   1 experimental group

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Data set
Procedure / Protocol
Treatment
Phenotype Measure / Variable (click to view)
Panel
No. of Strains
Sex
Age
Sample Size (Avg)
    HMDPpheno4 fear conditioning test (none) fear training, percent time spent near chamber walls, day1   [%]  ftr_thig   46801     pre-stimulus    post-stimulus HMDP w/par 94 m 10wks N=7
    HMDPpheno4 fear conditioning test (none) fear training, velocity, day 1   [cm/s]  ftr_vel   46811     pre-stimulus    post-stimulus HMDP w/par 94 m 10wks N=7
    HMDPpheno4 fear conditioning test (none) fear training, percent time immobile, day 1   [%]  ftr_imob   46821     pre-stimulus    post-stimulus HMDP w/par 94 m 10wks N=7
    HMDPpheno4 fear conditioning test (none) fear training activity burst to footshock, shock reactivity, day 1   [cm/s]  ftr_post_act_burst   46831 HMDP w/par 94 m 10wks N=7
    HMDPpheno4 fear conditioning test (none) contextual fear thigmotaxis, percent time spent near chamber walls, day 2   [%]  ctx_thig   46836 HMDP w/par 94 m 10wks N=7
    HMDPpheno4 fear conditioning test (none) contextual fear velocity, day 2   [cm/s]  ctx_vel   46841 HMDP w/par 94 m 10wks N=7
    HMDPpheno4 fear conditioning test (none) contextual fear percent time immobile, day 2   [%]  ctx_imob   46846 HMDP w/par 94 m 10wks N=7
    HMDPpheno4 fear conditioning test (none) cued fear thigmotaxis, percent time spent near chamber walls, day 3   [%]  thig   46851     pre-cue    cue HMDP w/par 94 m 10wks N=7
    HMDPpheno4 fear conditioning test (none) cued fear, velocity, day 3   [cm/s]  vel   46861     pre-cue    cue HMDP w/par 94 m 10wks N=7
    HMDPpheno4 fear conditioning test (none) cued fear, percent time immobile, day 3   [%]  imob   46871     pre-cue    cue HMDP w/par 94 m 10wks N=7
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