MPD: Phenotype measures mapped to MA:0000012, endocrine system

Phenotype measures associated with ontology term
MA:0000012 'endocrine system'

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All measures in this list are mapped to the ontology descendants of MA:0000012. None are mapped to MA:0000012 directly.

MA:0000116 adrenal gland
MA:0000127 pancreatic islet
MA:0000129 thyroid gland

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Attie2:99	Attie2	microscopy	high-fat high-sucrose diet	number of islets harvested per mouse after diet [n] islets 110716	DO population		both	19-26wks	N=242	2018

Attie2:100	Attie2	hormone quantification	high-fat high-sucrose diet	amount of insulin per islet after diet [ng/mL] INS_per_islet 110717	DO population		both	19-26wks	N=241	2018

Attie2:102	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to glucose [ng/mL] INS_GLU 110719 3.3 mM 8.3 mM 16.7 mM	DO population		both	19-26wks	N=242	2018

Attie2:105	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl [ng/mL] INS_GLU3p3_KCl 110722	DO population		both	19-26wks	N=240	2018

Attie2:106	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus 100 nM GLP-1 [ng/mL] INS_GLU8p3_GLP1 110723	DO population		both	19-26wks	N=240	2018

Attie2:107	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu) [ng/mL] INS_GLU8p3_AA 110724	DO population		both	19-26wks	N=240	2018

Attie2:108	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose plus 0.5 mM palmitic acid [ng/mL] INS_GLU16p7_PA 110725	DO population		both	19-26wks	N=240	2018

Attie2:109	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU8p3_fc_G3p3 110726	DO population		both	19-26wks	N=240	2018

Attie2:110	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose, expressed as fold-change over that observed with 3.3.mM glucose [ratio] INS_GLU16p7_fc_G3p3 110727	DO population		both	19-26wks	N=240	2018

Attie2:111	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU3p3__KCl_fc_G3p3 110728	DO population		both	19-26wks	N=240	2018

Attie2:112	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus 100 nM GLP-1, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU8p3_GLP1_fc_G3p3 110729	DO population		both	19-26wks	N=240	2018

Attie2:113	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu), expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU8p3_AA_fc_G3p3 110730	DO population		both	19-26wks	N=240	2018

Attie2:114	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose plus palmitic acid, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU16p7_PA_fc_G3p3 110731	DO population		both	19-26wks	N=240	2018

Attie2:115	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl, expressed as fold-change over that observed with 8.3 mM glucose [ratio] INS_GLU8p3_GLP1_fc_G8p3 110732	DO population		both	19-26wks	N=240	2018

Attie2:116	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu), expressed as fold-change over that observed with 8.3 mM glucose [ratio] INS_GLU8p3_AA_fc_G8p3 110733	DO population		both	19-26wks	N=240	2018

Attie2:117	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose plus 0.5 mM palmitic acid, expressed as fold-change over that observed with 16.7 mM glucose [ratio] INS_GLU16p7_PA_fc_G16p7 110734	DO population		both	19-26wks	N=240	2018

Attie2:118	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to glucose, expressed as a percentage of total insulin per mouse [%] INS_pct_GLU 110735 3.3 mM 8.3 mM 16.7 mM	DO population		both	19-26wks	N=241	2018

Attie2:121	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl, expressed as a percentage of total insulin per mouse [%] INS_GLU3p3_KCl_pct 110738	DO population		both	19-26wks	N=239	2018

Attie2:122	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus 100 nM GLP-1, expressed as a percentage of total insulin per mouse [%] INS_GLU8p3_GLP1_pct 110739	DO population		both	19-26wks	N=239	2018

Attie2:123	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu), expressed as a percentage of total insulin per mouse [%] INS_GLU8p3_AA_pct 110740	DO population		both	19-26wks	N=239	2018

Attie2:124	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose plus 0.5 mM palmitic acid, expressed as a percentage of total insulin per mouse [%] INS_GLU16p7_PA_pct 110741	DO population		both	19-26wks	N=239	2018

Attie2:125	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to glucose (geometric mean) [ng/mL] INS_gm_GLU 110742 3.3 mM 8.3 mM 16.7 mM	DO population		both	19-26wks	N=242	2018

Attie2:128	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl (geometric mean) [ng/mL] INS_gm_GLU3p3_KCl 110745	DO population		both	19-26wks	N=240	2018

Attie2:129	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus 100 nM GLP-1 (geometric mean) [ng/mL] INS_gm_GLU8p3_GLP1 110746	DO population		both	19-26wks	N=240	2018

Attie2:130	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu) (geometric mean) [ng/mL] INS_gm_GLU8p3_AA 110747	DO population		both	19-26wks	N=240	2018

Attie2:131	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose plus 0.5 mM palmitic acid (geometric mean) [ng/mL] INS_gm_GLU16p7_PA 110748	DO population		both	19-26wks	N=240	2018

Attie2:132	Attie2	hormone quantification	high-fat high-sucrose diet	amount of glucagon per islet after diet [ng/mL] GCG_per_islet 110749	DO population		both	19-26wks	N=241	2018

Attie2:133	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo glucagon secretion after diet in response to 3.3 mM glucose plus 40 mM KCl [ng/mL] GCG_GLU3p3_KCl 110750	DO population		both	19-26wks	N=182	2018

Attie2:134	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo glucagon secretion after diet in response to 3.3 mM glucose plus 40 mM KCl, expressed as a percentage of total glucagon per mouse [%] GCG_GLU3p3_KCl_pct 110751	DO population		both	19-26wks	N=182	2018

Deschepper1:17	Deschepper1	organ weights	(none)	adrenal weight [mg] adrenal 10417 right left both	inbred	13	both	10wks	N=10	2004

Deschepper1:18	Deschepper1	organ weights	(none)	adrenal weight, normalized to body weight [mg] adrenal_adj 10418 right left both	inbred	13	both	10wks	N=10	2004

DiCurzio1:2	DiCurzio1	organ weights	(none)	adrenal weights [mg] adr_wt 36602 left right	BXD w/par	66	both	7-10wks*	N=4	2010

DiCurzio1:4	DiCurzio1	organ weights	(none)	mean weight of both adrenals [mg] adr_wt_ave 36604	BXD w/par	66	both	7-10wks*	N=4	2010

DiCurzio1:5	DiCurzio1	organ weights	(none)	total weight of adrenals adjusted to body weight (x10^-3) [mg] adr_adj_bw 36605	BXD w/par	66	both	7-10wks*	N=4	2010

DiCurzio1:6	DiCurzio1	histopathology	(none)	adrenal total width, diameter [µm] adr_width 36606	BXD w/par	66	both	7-10wks*	N=3	2010

DiCurzio1:7	DiCurzio1	histopathology	(none)	adrenal medulla width [µm] adr_medul_width 36607	BXD w/par	66	both	7-10wks*	N=3	2010

DiCurzio1:8	DiCurzio1	histopathology	(none)	adrenal cortex zona glomerulosa thickness [µm] adr_glome_width 36608	BXD w/par	66	both	7-10wks*	N=3	2010

DiCurzio1:9	DiCurzio1	histopathology	(none)	adrenal cortex zona intermedia thickness [µm] adr_inter_width 36609	BXD w/par	66	both	7-10wks*	N=3	2010

DiCurzio1:10	DiCurzio1	histopathology	(none)	adrenal cortex zona fasciculata thickness [µm] adr_fasci_width 36610	BXD w/par	66	both	7-10wks*	N=3	2010

DiCurzio1:11	DiCurzio1	histopathology	(none)	adrenal cortex zona reticularis thickness [µm] adr_retic_width 36611	BXD w/par	66	both	7-10wks*	N=3	2010

DiCurzio1:12	DiCurzio1	histopathology	(none)	adrenal cortex X-zone thickness [µm] adr_Xzone_width 36612	BXD w/par	66	both	7-10wks*	N=3	2010

DiCurzio1:14	DiCurzio1	histopathology	(none)	adrenal glands, presence of X-zone (0=no; 1=yes) [score] Xzone_presence 36614	BXD w/par	66	both	7-10wks*	N=4	2010

DiCurzio1:15	DiCurzio1	histopathology	(none)	adrenal glands, presence of lipoid structures in females (0=none; 1=outside X-zone; 2=within X-zone) [score] lipoid_presence 36615	BXD w/par	66	f	7-10wks*	N=4	2010

Solberg1:9	Solberg1	hormone quantification	(none)	thyroid-stimulating hormone [ng/mL] TSH 15009	QTL population		both	15wks	N=243	2004

Solberg1:15	Solberg1	organ weights	(none)	adrenal weight [g] adrenalwt 15015	QTL population		both	17wks	N=243	2004

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