Project measures / variables set:   Wiltshire4   monocytes_Sel

ID, description, units MPD:52473   monocytes_Sel   monocytes, percent viability   [%]  
selumetinib study
Measures
• dose [µM]:    • control    • 0.046    • 0.137    • 1.235    • 11.1    • 100
Data set, strains Wiltshire4   inbred w/CC7   34 strains     sex: m     age: 10wks
Procedure immune cell quantification
Comparisoncontrol group vs. multiple treatment / dosage groups
Ontology mappings

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Created with Highcharts 6.0.7Chart context menuMaleWiltshire452473,52474,52475,52476,52477,52478monocytes, percent viabilitycontrol0.0460.1371.23511.1100129S1/SvImJ129X1/SvJA/JAKR/JBALB/cByJBTBR T<+> Itpr3/JBUB/BnJC3H/HeJC57BL/6JC57BLKS/JC58/JCBA/JCZECHII/EiJDBA/2JFVB/NJI/LnJKK/HlJLG/JLP/JMA/MyJNOD/ShiLtJNON/ShiLtJNZB/BlNJNZO/HlLtJNZW/LacJPERA/EiJPL/JPWD/PhJPWK/PhJRIIIS/JSEA/GnJSJL/JSM/JWSB/EiJ406080100120140160180
Strains
measured value [%]


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Wiltshire4 - monocytes, percent viability
Created with Highcharts 6.0.7measureChart context menuMale129S1/SvImJ129X1/SvJA/JAKR/JBALB/cByJBTBR T+ Itpr3tf/JBUB/BnJC3H/HeJC57BL/6JC57BLKS/JC58/JCBA/JCZECHII/EiJDBA/2JFVB/NJI/LnJKK/HlJLG/JLP/JMA/MyJNOD/ShiLtJNON/ShiLtJNZB/BlNJNZO/HlLtJNZW/LacJPERA/EiJPL/JPWD/PhJPWK/PhJRIIIS/JSEA/GnJSJL/JSM/JWSB/EiJcontroldose: 0.046 &micro;Mdose: 0.137 &micro;Mdose: 1.235 &micro;Mdose: 11.1 &micro;Mdose: 100 &micro;M255075100125150175
%


  ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary     

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
dose 5 1567.7569 313.5514 1.974 0.0807
strain 33 30509.6172 924.5339 5.8205 < 0.0001
dose:strain 165 34688.8149 210.2352 1.3236 0.0098
Residuals 594 94351.7607 158.8413

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDTreatmentMeasure / Variable Description PanelStrains
tested		SexAge
Wiltshire4 52473 immune cell quantification selumetinib monocytes, percent viability   [%]   control  monocytes_Sel_ctrl inbred w/CC7 34 m 10wks
Wiltshire4 52474 immune cell quantification selumetinib monocytes, percent viability   [%]   dose: 0.046 µM  monocytes_Sel_A inbred w/CC7 34 m 10wks
Wiltshire4 52475 immune cell quantification selumetinib monocytes, percent viability   [%]   dose: 0.137 µM  monocytes_Sel_B inbred w/CC7 34 m 10wks
Wiltshire4 52476 immune cell quantification selumetinib monocytes, percent viability   [%]   dose: 1.235 µM  monocytes_Sel_C inbred w/CC7 34 m 10wks
Wiltshire4 52477 immune cell quantification selumetinib monocytes, percent viability   [%]   dose: 11.1 µM  monocytes_Sel_D inbred w/CC7 34 m 10wks
Wiltshire4 52478 immune cell quantification selumetinib monocytes, percent viability   [%]   dose: 100 µM  monocytes_Sel_E inbred w/CC7 34 m 10wks



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