Project measure / variable:   Jentsch2   discrimination3_FR5

ID, description, units MPD:49727   discrimination3_FR5   Fixed ratio 5 - discrimination index between active and inactive levers   [%]  day 3  
cocaine study
Data set, strains Jentsch2   BXD   4 strains     sex: both     age: 8-17wks
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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Jentsch2 - Fixed ratio 5 - discrimination index between active and inactive levers day 3



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested2 strains4 strains
Mean of the strain means97.1   % 88.9   %
Median of the strain means97.1   % 88.8   %
SD of the strain means± 1.70 ± 2.49
Coefficient of variation (CV)0.0175 0.0280
Min–max range of strain means95.9   –   98.3   % 86.2   –   91.9   %
Mean sample size per strain4.5   mice 7.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 137.1462 137.1462 7.7335 0.0123
strain 1 0.2739 0.2739 0.0154 0.9025
sex:strain 1 18.632 18.632 1.0506 0.3189
Residuals 18 319.2132 17.7341


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD31/TyJ m 86.2 7.42   7 2.8 0.086 72.4, 93.9 -1.09
BXD38/TyJ f 95.9 4.2   7 1.59 0.0438 87.5, 98.9 -0.71
BXD38/TyJ m 91.9 4.77   10 1.51 0.0519 80.0, 97.6 1.21
BXD42/TyJ m 87.7 9.21   9 3.07 0.105 72.3, 98.8 -0.48
BXD68/RwwJ f 98.3 0.438   2   0.31 0.00446 98.0, 98.6 0.71
BXD68/RwwJ m 89.8 2.02   3 1.17 0.0225 87.7, 91.7 0.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ f 95.9214 1.5917 99.2654 92.5774
BXD38/TyJ m 91.856 1.3317 94.6538 89.0582
BXD68/RwwJ f 98.33 2.9778 104.586 92.074
BXD68/RwwJ m 89.7867 2.4313 94.8947 84.6786


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ both 93.8887 1.0376 96.0687 91.7087
BXD68/RwwJ both 94.0583 1.9221 98.0966 90.0201




GWAS analysis not available: SNP data is not available for enough strains (at least 4)