Project measure / variable:   Jentsch2   discrimination5_FR5

ID, description, units MPD:49728   discrimination5_FR5   Fixed ratio 5 - discrimination index between active and inactive levers   [%]  day 5  
cocaine study
Data set, strains Jentsch2   BXD   4 strains     sex: both     age: 8-17wks
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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Jentsch2 - Fixed ratio 5 - discrimination index between active and inactive levers day 5



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested2 strains4 strains
Mean of the strain means98.8   % 92.3   %
Median of the strain means98.8   % 92.3   %
SD of the strain means± 1.34 ± 2.59
Coefficient of variation (CV)0.0136 0.0281
Min–max range of strain means97.9   –   99.8   % 89.7   –   94.7   %
Mean sample size per strain4.5   mice 7.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 83.117 83.117 5.0963 0.0366
strain 1 4.0047 4.0047 0.2455 0.6262
sex:strain 1 2.0482 2.0482 0.1256 0.7272
Residuals 18 293.5677 16.3093


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD31/TyJ m 89.7 2.78   7 1.05 0.031 85.7, 93.9 -0.99
BXD38/TyJ f 97.9 2.77   7 1.05 0.0283 93.9, 100.0 -0.71
BXD38/TyJ m 94.3 5.23   10 1.65 0.0555 88.1, 100.0 0.78
BXD42/TyJ m 90.4 5.56   9 1.85 0.0615 82.0, 97.4 -0.72
BXD68/RwwJ f 99.8 0.233   2   0.165 0.00234 99.7, 100.0 0.71
BXD68/RwwJ m 94.7 0.766   3 0.442 0.00808 93.8, 95.3 0.94


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ f 97.93 1.5264 101.1369 94.7231
BXD38/TyJ m 94.303 1.2771 96.986 91.62
BXD68/RwwJ f 99.835 2.8556 105.8345 93.8355
BXD68/RwwJ m 94.7233 2.3316 99.6219 89.8248


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ both 96.1165 0.9951 98.2071 94.0259
BXD68/RwwJ both 97.2792 1.8433 101.1518 93.4065




GWAS analysis not available: SNP data is not available for enough strains (at least 4)