Project measure / variable:   Berndt2   duty_cycle_mch20

ID, description, units MPD:35137   duty_cycle_mch20   duty cycle   [ratio]  20 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - duty cycle 20 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.346   ratio 0.362   ratio
Median of the strain means0.349   ratio 0.359   ratio
SD of the strain means± 0.0345 ± 0.0300
Coefficient of variation (CV)0.1000 0.0829
Min–max range of strain means0.258   –   0.421   ratio 0.286   –   0.414   ratio
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0301 0.0301 26.0332 < 0.0001
strain 28 0.402 0.0144 12.4205 < 0.0001
sex:strain 28 0.0685 0.0024 2.1175 0.0009
Residuals 412 0.4762 0.0012


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.361 0.0197   8 0.00696 0.0545 0.339, 0.405 0.45
129S1/SvImJ m 0.36 0.0277   8 0.0098 0.0769 0.321, 0.405 -0.08
A/J f 0.361 0.052   8 0.0184 0.144 0.295, 0.457 0.45
A/J m 0.338 0.0331   8 0.0117 0.0982 0.285, 0.371 -0.81
AKR/J f 0.369 0.0378   8 0.0134 0.102 0.333, 0.444 0.68
AKR/J m 0.376 0.0289   8 0.0102 0.0769 0.335, 0.409 0.45
BALB/cByJ f 0.368 0.0247   8 0.00872 0.067 0.331, 0.41 0.65
BALB/cByJ m 0.374 0.0255   8 0.00902 0.0683 0.337, 0.417 0.39
BALB/cJ f 0.382 0.0213   10 0.00674 0.0558 0.358, 0.419 1.06
BALB/cJ m 0.394 0.0252   10 0.00796 0.0639 0.357, 0.424 1.05
BTBR T+ Itpr3tf/J f 0.344 0.034   8 0.012 0.0989 0.289, 0.394 -0.04
BTBR T+ Itpr3tf/J m 0.368 0.0316   8 0.0112 0.0858 0.299, 0.39 0.19
BUB/BnJ f 0.342 0.0353   7 0.0133 0.103 0.272, 0.372 -0.1
BUB/BnJ m 0.328 0.0443   8 0.0157 0.135 0.262, 0.4 -1.14
C3H/HeJ f 0.318 0.0224   8 0.00793 0.0705 0.29, 0.359 -0.8
C3H/HeJ m 0.317 0.0556   8 0.0197 0.176 0.227, 0.38 -1.51
C57BL/10J f 0.335 0.0262   8 0.00926 0.0782 0.288, 0.37 -0.31
C57BL/10J m 0.347 0.0124   7 0.0047 0.0359 0.32, 0.357 -0.51
C57BL/6J f 0.36 0.0438   7 0.0165 0.122 0.314, 0.414 0.42
C57BL/6J m 0.373 0.0311   13 0.00861 0.0832 0.317, 0.433 0.35
C57BLKS/J f 0.383 0.0512   11 0.0155 0.134 0.29, 0.463 1.08
C57BLKS/J m 0.413 0.0183   8 0.00647 0.0444 0.383, 0.433 1.68
C57BR/cdJ f 0.371 0.0285   6 0.0116 0.0768 0.317, 0.397 0.74
C57BR/cdJ m 0.358 0.0322   8 0.0114 0.0898 0.295, 0.412 -0.15
C57L/J f 0.363 0.0201   8 0.00712 0.0555 0.342, 0.402 0.51
C57L/J m 0.392 0.0144   8 0.00509 0.0367 0.377, 0.421 0.99
CBA/J f 0.385 0.0133   8 0.00469 0.0344 0.367, 0.405 1.14
CBA/J m 0.386 0.0138   8 0.00486 0.0356 0.357, 0.403 0.79
CE/J f 0.359 0.0144   8 0.0051 0.0402 0.335, 0.379 0.39
CE/J m 0.357 0.0199   9 0.00664 0.0558 0.331, 0.39 -0.18
DBA/1J f 0.345 0.0321   10 0.0102 0.0932 0.301, 0.413 -0.02
DBA/1J m 0.337 0.0326   8 0.0115 0.0968 0.293, 0.383 -0.84
DBA/2J f 0.344 0.0419   8 0.0148 0.122 0.268, 0.396 -0.04
DBA/2J m 0.368 0.023   10 0.00726 0.0624 0.339, 0.404 0.19
FVB/NJ f 0.331 0.0257   8 0.00909 0.0777 0.296, 0.367 -0.42
FVB/NJ m 0.414 0.041   7 0.0155 0.099 0.369, 0.464 1.72
I/LnJ f 0.349 0.0748   7 0.0283 0.214 0.223, 0.441 0.1
I/LnJ m 0.4 0.0392   5 0.0175 0.098 0.343, 0.444 1.25
KK/HlJ f 0.358 0.0518   8 0.0183 0.145 0.257, 0.405 0.36
KK/HlJ m 0.378 0.0499   6 0.0204 0.132 0.289, 0.434 0.52
LP/J f 0.279 0.064   8 0.0226 0.229 0.16, 0.345 -1.93
LP/J m 0.349 0.0375   8 0.0133 0.108 0.302, 0.396 -0.45
NOD/ShiLtJ f 0.339 0.0313   8 0.0111 0.0923 0.286, 0.384 -0.19
NOD/ShiLtJ m 0.359 0.0341   8 0.0121 0.0951 0.296, 0.399 -0.11
NON/ShiLtJ f 0.302 0.0298   8 0.0106 0.0987 0.262, 0.359 -1.26
NON/ShiLtJ m 0.35 0.0429   8 0.0152 0.122 0.283, 0.413 -0.41
NZW/LacJ f 0.295 0.0477   8 0.0169 0.162 0.206, 0.354 -1.46
NZW/LacJ m 0.339 0.0287   8 0.0101 0.0847 0.293, 0.376 -0.78
PL/J f 0.258 0.0322   8 0.0114 0.125 0.22, 0.32 -2.53
PL/J m 0.286 0.0176   8 0.00622 0.0615 0.26, 0.306 -2.54
RIIIS/J f 0.363 0.0264   8 0.00933 0.0727 0.323, 0.394 0.51
RIIIS/J m 0.352 0.0262   8 0.00927 0.0745 0.308, 0.389 -0.35
SJL/J f 0.297 0.0282   8 0.00996 0.0949 0.263, 0.341 -1.41
SJL/J m 0.327 0.0338   8 0.012 0.103 0.292, 0.38 -1.18
SM/J f 0.421 0.0265   8 0.00938 0.063 0.38, 0.461 2.18
SM/J m 0.413 0.0299   8 0.0106 0.0723 0.353, 0.443 1.68
SWR/J f 0.339 0.0248   8 0.00877 0.0731 0.303, 0.378 -0.19
SWR/J m 0.356 0.0209   9 0.00697 0.0587 0.332, 0.385 -0.21


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.361 0.012 0.3846 0.3374
129S1/SvImJ m 0.3604 0.012 0.384 0.3367
A/J f 0.3615 0.012 0.3851 0.3379
A/J m 0.3375 0.012 0.3611 0.3139
AKR/J f 0.3689 0.012 0.3925 0.3452
AKR/J m 0.3755 0.012 0.3991 0.3519
BALB/cByJ f 0.368 0.012 0.3916 0.3444
BALB/cByJ m 0.3738 0.012 0.3974 0.3501
BALB/cJ f 0.3818 0.0108 0.4029 0.3607
BALB/cJ m 0.3943 0.0108 0.4154 0.3732
BTBR T+ Itpr3tf/J f 0.3438 0.012 0.3674 0.3201
BTBR T+ Itpr3tf/J m 0.3683 0.012 0.3919 0.3446
BUB/BnJ f 0.3421 0.0129 0.3674 0.3169
BUB/BnJ m 0.3284 0.012 0.352 0.3047
C3H/HeJ f 0.3181 0.012 0.3418 0.2945
C3H/HeJ m 0.3166 0.012 0.3403 0.293
C57BL/10J f 0.3353 0.012 0.3589 0.3116
C57BL/10J m 0.3466 0.0129 0.3718 0.3213
C57BL/6J f 0.3599 0.0129 0.3851 0.3346
C57BL/6J m 0.3732 0.0094 0.3918 0.3547
C57BLKS/J f 0.383 0.0103 0.4032 0.3628
C57BLKS/J m 0.4128 0.012 0.4364 0.3891
C57BR/cdJ f 0.371 0.0139 0.3983 0.3437
C57BR/cdJ m 0.3584 0.012 0.382 0.3347
C57L/J f 0.3629 0.012 0.3865 0.3392
C57L/J m 0.3923 0.012 0.4159 0.3686
CBA/J f 0.3852 0.012 0.4089 0.3616
CBA/J m 0.3865 0.012 0.4101 0.3629
CE/J f 0.3594 0.012 0.383 0.3357
CE/J m 0.3568 0.0113 0.3791 0.3345
DBA/1J f 0.345 0.0108 0.3661 0.3239
DBA/1J m 0.3373 0.012 0.3609 0.3136
DBA/2J f 0.344 0.012 0.3676 0.3204
DBA/2J m 0.3681 0.0108 0.3892 0.347
FVB/NJ f 0.331 0.012 0.3546 0.3074
FVB/NJ m 0.4137 0.0129 0.439 0.3885
I/LnJ f 0.3487 0.0129 0.374 0.3235
I/LnJ m 0.3996 0.0152 0.4295 0.3697
KK/HlJ f 0.3581 0.012 0.3818 0.3345
KK/HlJ m 0.3777 0.0139 0.405 0.3504
LP/J f 0.2794 0.012 0.303 0.2557
LP/J m 0.3489 0.012 0.3725 0.3252
NOD/ShiLtJ f 0.3385 0.012 0.3621 0.3149
NOD/ShiLtJ m 0.3588 0.012 0.3824 0.3351
NON/ShiLtJ f 0.3023 0.012 0.3259 0.2786
NON/ShiLtJ m 0.3503 0.012 0.3739 0.3266
NZW/LacJ f 0.2949 0.012 0.3185 0.2712
NZW/LacJ m 0.3389 0.012 0.3625 0.3152
PL/J f 0.2575 0.012 0.2811 0.2339
PL/J m 0.2863 0.012 0.3099 0.2626
RIIIS/J f 0.3631 0.012 0.3868 0.3395
RIIIS/J m 0.3518 0.012 0.3754 0.3281
SJL/J f 0.297 0.012 0.3206 0.2734
SJL/J m 0.327 0.012 0.3506 0.3034
SM/J f 0.4214 0.012 0.445 0.3977
SM/J m 0.4131 0.012 0.4368 0.3895
SWR/J f 0.3394 0.012 0.363 0.3157
SWR/J m 0.3559 0.0113 0.3782 0.3336


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.3607 0.0085 0.3774 0.344
A/J both 0.3495 0.0085 0.3662 0.3328
AKR/J both 0.3722 0.0085 0.3889 0.3555
BALB/cByJ both 0.3709 0.0085 0.3876 0.3542
BALB/cJ both 0.3881 0.0076 0.403 0.3731
BTBR T+ Itpr3tf/J both 0.356 0.0085 0.3727 0.3393
BUB/BnJ both 0.3353 0.0088 0.3526 0.318
C3H/HeJ both 0.3174 0.0085 0.3341 0.3007
C57BL/10J both 0.3409 0.0088 0.3582 0.3236
C57BL/6J both 0.3665 0.008 0.3822 0.3509
C57BLKS/J both 0.3979 0.0079 0.4134 0.3823
C57BR/cdJ both 0.3647 0.0092 0.3827 0.3466
C57L/J both 0.3776 0.0085 0.3943 0.3609
CBA/J both 0.3859 0.0085 0.4026 0.3692
CE/J both 0.3581 0.0083 0.3743 0.3418
DBA/1J both 0.3411 0.0081 0.357 0.3253
DBA/2J both 0.3561 0.0081 0.3719 0.3402
FVB/NJ both 0.3724 0.0088 0.3897 0.3551
I/LnJ both 0.3742 0.01 0.3937 0.3546
KK/HlJ both 0.3679 0.0092 0.3859 0.3498
LP/J both 0.3141 0.0085 0.3308 0.2974
NOD/ShiLtJ both 0.3486 0.0085 0.3653 0.3319
NON/ShiLtJ both 0.3263 0.0085 0.343 0.3095
NZW/LacJ both 0.3169 0.0085 0.3336 0.3002
PL/J both 0.2719 0.0085 0.2886 0.2552
RIIIS/J both 0.3574 0.0085 0.3741 0.3407
SJL/J both 0.312 0.0085 0.3287 0.2953
SM/J both 0.4173 0.0085 0.434 0.4005
SWR/J both 0.3476 0.0083 0.3639 0.3314




  GWAS USING LINEAR MIXED MODELS