Project measure / variable:   Berndt2   duty_cycle_saline

ID, description, units MPD:35134   duty_cycle_saline   duty cycle   [ratio]  saline  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - duty cycle saline

RIIIS/JSM/JBTBR T<+> Itpr3<tf>/JDBA/2JC57BR/cdJSJL/JNZW/LacJCE/JFVB/NJDBA/1JSWR/JBALB/cJBUB/BnJAKR/JBALB/cByJC57BL/10JA/JNON/ShiLtJC57BL/6JLP/JCBA/JC3H/HeJC57BLKS/JC57L/J129S1/SvImJI/LnJPL/JKK/HlJNOD/ShiLtJ ratio 0.200.220.240.260.280.300.320.340.360.380.400.420.44femalemale


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.295   ratio 0.304   ratio
Median of the strain means0.293   ratio 0.305   ratio
SD of the strain means± 0.0287 ± 0.0260
Coefficient of variation (CV)0.0972 0.0854
Min–max range of strain means0.241   –   0.367   ratio 0.260   –   0.347   ratio
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.009 0.009 7.8381 0.0054
strain 28 0.2815 0.0101 8.7222 < 0.0001
sex:strain 28 0.0565 0.002 1.7512 0.0113
Residuals 412 0.4749 0.0012


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain
Sex
Mean
SD
N mice
SEM
CV
Min, Max
Z score
129S1/SvImJ f 0.258 0.0432   8 0.0153 0.167 0.194, 0.321 -1.3
129S1/SvImJ m 0.29 0.0313   8 0.0111 0.108 0.232, 0.332 -0.54
A/J f 0.29 0.0293   8 0.0104 0.101 0.246, 0.319 -0.19
A/J m 0.299 0.0224   8 0.00794 0.075 0.271, 0.325 -0.2
AKR/J f 0.311 0.0445   8 0.0157 0.143 0.278, 0.414 0.54
AKR/J m 0.288 0.0293   8 0.0104 0.102 0.229, 0.313 -0.62
BALB/cByJ f 0.287 0.0269   8 0.00949 0.0936 0.25, 0.332 -0.29
BALB/cByJ m 0.307 0.0337   8 0.0119 0.11 0.268, 0.361 0.11
BALB/cJ f 0.3 0.057   10 0.018 0.19 0.23, 0.431 0.16
BALB/cJ m 0.317 0.0377   10 0.0119 0.119 0.247, 0.378 0.5
BTBR T+ Itpr3tf/J f 0.32 0.0335   8 0.0118 0.105 0.281, 0.382 0.85
BTBR T+ Itpr3tf/J m 0.347 0.0389   8 0.0137 0.112 0.289, 0.396 1.65
BUB/BnJ f 0.298 0.0308   7 0.0117 0.103 0.248, 0.342 0.09
BUB/BnJ m 0.305 0.0103   8 0.00363 0.0337 0.293, 0.316 0.04
C3H/HeJ f 0.277 0.0283   8 0.01 0.102 0.249, 0.33 -0.64
C3H/HeJ m 0.281 0.0236   8 0.00834 0.084 0.238, 0.317 -0.89
C57BL/10J f 0.278 0.0314   8 0.0111 0.113 0.242, 0.344 -0.61
C57BL/10J m 0.314 0.0241   7 0.00911 0.0767 0.28, 0.36 0.38
C57BL/6J f 0.29 0.0448   7 0.0169 0.154 0.24, 0.378 -0.19
C57BL/6J m 0.279 0.0401   13 0.0111 0.144 0.213, 0.341 -0.97
C57BLKS/J f 0.293 0.0548   11 0.0165 0.187 0.205, 0.369 -0.09
C57BLKS/J m 0.26 0.0424   8 0.015 0.163 0.194, 0.332 -1.7
C57BR/cdJ f 0.313 0.0618   6 0.0252 0.198 0.245, 0.409 0.61
C57BR/cdJ m 0.339 0.0467   8 0.0165 0.138 0.292, 0.408 1.34
C57L/J f 0.284 0.0428   8 0.0151 0.151 0.224, 0.343 -0.4
C57L/J m 0.266 0.0336   8 0.0119 0.126 0.236, 0.314 -1.47
CBA/J f 0.275 0.0192   8 0.0068 0.0698 0.236, 0.297 -0.71
CBA/J m 0.287 0.027   8 0.00955 0.0942 0.254, 0.337 -0.66
CE/J f 0.325 0.038   8 0.0134 0.117 0.248, 0.367 1.03
CE/J m 0.314 0.0231   9 0.00771 0.0736 0.277, 0.338 0.38
DBA/1J f 0.325 0.0441   10 0.0139 0.136 0.265, 0.401 1.03
DBA/1J m 0.31 0.0275   8 0.00971 0.0885 0.273, 0.356 0.23
DBA/2J f 0.316 0.0334   8 0.0118 0.106 0.255, 0.353 0.72
DBA/2J m 0.338 0.0173   10 0.00548 0.0513 0.316, 0.368 1.31
FVB/NJ f 0.317 0.0146   8 0.00515 0.046 0.296, 0.34 0.75
FVB/NJ m 0.319 0.0199   7 0.00752 0.0623 0.296, 0.348 0.57
I/LnJ f 0.263 0.0249   7 0.00942 0.0948 0.227, 0.292 -1.13
I/LnJ m 0.284 0.0238   5 0.0107 0.0839 0.261, 0.318 -0.77
KK/HlJ f 0.261 0.0296   8 0.0105 0.113 0.23, 0.32 -1.2
KK/HlJ m 0.271 0.0334   6 0.0136 0.123 0.226, 0.314 -1.27
LP/J f 0.27 0.0241   8 0.00852 0.0894 0.235, 0.314 -0.89
LP/J m 0.297 0.0329   8 0.0116 0.111 0.259, 0.342 -0.27
NOD/ShiLtJ f 0.241 0.0223   8 0.00789 0.0924 0.217, 0.278 -1.9
NOD/ShiLtJ m 0.264 0.0327   8 0.0116 0.124 0.219, 0.324 -1.54
NON/ShiLtJ f 0.272 0.0263   8 0.00931 0.0967 0.234, 0.309 -0.82
NON/ShiLtJ m 0.303 0.0284   8 0.01 0.0935 0.263, 0.348 -0.04
NZW/LacJ f 0.303 0.0257   8 0.00907 0.0846 0.269, 0.343 0.26
NZW/LacJ m 0.341 0.0293   8 0.0103 0.0857 0.29, 0.379 1.42
PL/J f 0.262 0.0507   8 0.0179 0.194 0.197, 0.37 -1.16
PL/J m 0.275 0.0489   8 0.0173 0.178 0.241, 0.391 -1.12
RIIIS/J f 0.354 0.0379   8 0.0134 0.107 0.315, 0.413 2.04
RIIIS/J m 0.338 0.0161   8 0.00568 0.0475 0.31, 0.354 1.31
SJL/J f 0.303 0.0209   8 0.00739 0.0689 0.264, 0.324 0.26
SJL/J m 0.345 0.0241   8 0.00853 0.0699 0.314, 0.385 1.58
SM/J f 0.367 0.0162   8 0.00574 0.0443 0.343, 0.387 2.49
SM/J m 0.323 0.0338   8 0.0119 0.105 0.268, 0.389 0.73
SWR/J f 0.315 0.0294   8 0.0104 0.0936 0.291, 0.379 0.68
SWR/J m 0.317 0.0283   9 0.00944 0.0894 0.282, 0.367 0.5


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.2581 0.012 0.2817 0.2345
129S1/SvImJ m 0.2896 0.012 0.3132 0.266
A/J f 0.2895 0.012 0.3131 0.2659
A/J m 0.2994 0.012 0.323 0.2758
AKR/J f 0.3115 0.012 0.3351 0.2879
AKR/J m 0.2878 0.012 0.3113 0.2642
BALB/cByJ f 0.287 0.012 0.3106 0.2634
BALB/cByJ m 0.3072 0.012 0.3308 0.2837
BALB/cJ f 0.3003 0.0107 0.3214 0.2792
BALB/cJ m 0.3168 0.0107 0.3379 0.2957
BTBR T+ Itpr3tf/J f 0.3201 0.012 0.3437 0.2965
BTBR T+ Itpr3tf/J m 0.3472 0.012 0.3708 0.3237
BUB/BnJ f 0.2984 0.0128 0.3237 0.2732
BUB/BnJ m 0.3046 0.012 0.3282 0.281
C3H/HeJ f 0.2769 0.012 0.3005 0.2533
C3H/HeJ m 0.2809 0.012 0.3045 0.2573
C57BL/10J f 0.278 0.012 0.3016 0.2544
C57BL/10J m 0.314 0.0128 0.3392 0.2888
C57BL/6J f 0.29 0.0128 0.3152 0.2648
C57BL/6J m 0.279 0.0094 0.2975 0.2605
C57BLKS/J f 0.2931 0.0102 0.3132 0.273
C57BLKS/J m 0.26 0.012 0.2836 0.2364
C57BR/cdJ f 0.3127 0.0139 0.3399 0.2854
C57BR/cdJ m 0.3394 0.012 0.363 0.3158
C57L/J f 0.2837 0.012 0.3073 0.2602
C57L/J m 0.2662 0.012 0.2898 0.2427
CBA/J f 0.2755 0.012 0.2991 0.2519
CBA/J m 0.2868 0.012 0.3103 0.2632
CE/J f 0.3252 0.012 0.3488 0.3017
CE/J m 0.3143 0.0113 0.3366 0.2921
DBA/1J f 0.3248 0.0107 0.3459 0.3037
DBA/1J m 0.3102 0.012 0.3338 0.2867
DBA/2J f 0.3164 0.012 0.34 0.2928
DBA/2J m 0.338 0.0107 0.3591 0.3169
FVB/NJ f 0.3169 0.012 0.3405 0.2933
FVB/NJ m 0.3193 0.0128 0.3445 0.2941
I/LnJ f 0.2631 0.0128 0.2884 0.2379
I/LnJ m 0.2842 0.0152 0.314 0.2544
KK/HlJ f 0.2614 0.012 0.285 0.2378
KK/HlJ m 0.2712 0.0139 0.2984 0.2439
LP/J f 0.2695 0.012 0.2931 0.2459
LP/J m 0.2972 0.012 0.3208 0.2737
NOD/ShiLtJ f 0.2415 0.012 0.2651 0.2179
NOD/ShiLtJ m 0.2644 0.012 0.288 0.2408
NON/ShiLtJ f 0.2721 0.012 0.2957 0.2485
NON/ShiLtJ m 0.3035 0.012 0.3271 0.2799
NZW/LacJ f 0.3035 0.012 0.3271 0.2799
NZW/LacJ m 0.3412 0.012 0.3648 0.3177
PL/J f 0.2619 0.012 0.2855 0.2383
PL/J m 0.2752 0.012 0.2988 0.2517
RIIIS/J f 0.3537 0.012 0.3773 0.3302
RIIIS/J m 0.3381 0.012 0.3617 0.3145
SJL/J f 0.3034 0.012 0.327 0.2798
SJL/J m 0.3454 0.012 0.369 0.3218
SM/J f 0.367 0.012 0.3906 0.3434
SM/J m 0.3225 0.012 0.3461 0.2989
SWR/J f 0.3145 0.012 0.3381 0.2909
SWR/J m 0.3168 0.0113 0.339 0.2945


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.2739 0.0085 0.2906 0.2572
A/J both 0.2944 0.0085 0.3111 0.2778
AKR/J both 0.2996 0.0085 0.3163 0.2829
BALB/cByJ both 0.2971 0.0085 0.3138 0.2804
BALB/cJ both 0.3085 0.0076 0.3235 0.2936
BTBR T+ Itpr3tf/J both 0.3337 0.0085 0.3504 0.317
BUB/BnJ both 0.3015 0.0088 0.3188 0.2843
C3H/HeJ both 0.2789 0.0085 0.2956 0.2622
C57BL/10J both 0.296 0.0088 0.3133 0.2787
C57BL/6J both 0.2845 0.008 0.3001 0.2689
C57BLKS/J both 0.2765 0.0079 0.2921 0.261
C57BR/cdJ both 0.326 0.0092 0.344 0.308
C57L/J both 0.275 0.0085 0.2917 0.2583
CBA/J both 0.2811 0.0085 0.2978 0.2644
CE/J both 0.3198 0.0082 0.336 0.3036
DBA/1J both 0.3175 0.0081 0.3334 0.3017
DBA/2J both 0.3272 0.0081 0.343 0.3114
FVB/NJ both 0.3181 0.0088 0.3354 0.3008
I/LnJ both 0.2737 0.0099 0.2932 0.2541
KK/HlJ both 0.2663 0.0092 0.2843 0.2482
LP/J both 0.2834 0.0085 0.3001 0.2667
NOD/ShiLtJ both 0.2529 0.0085 0.2696 0.2363
NON/ShiLtJ both 0.2878 0.0085 0.3045 0.2711
NZW/LacJ both 0.3224 0.0085 0.3391 0.3057
PL/J both 0.2686 0.0085 0.2852 0.2519
RIIIS/J both 0.3459 0.0085 0.3626 0.3293
SJL/J both 0.3244 0.0085 0.3411 0.3077
SM/J both 0.3447 0.0085 0.3614 0.3281
SWR/J both 0.3156 0.0082 0.3319 0.2994




  GWAS USING LINEAR MIXED MODELS

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