Project measure / variable:   Berndt2   breath_freq_mch5

ID, description, units MPD:35109   breath_freq_mch5   breath frequency   [n/min]  5 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - breath frequency 5 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means240   n/min 241   n/min
Median of the strain means238   n/min 243   n/min
SD of the strain means± 33.8 ± 40.4
Coefficient of variation (CV)0.141 0.168
Min–max range of strain means190   –   317   n/min 183   –   345   n/min
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 95.1212 95.1212 0.0537 0.8169
strain 28 551489.0042 19696.0359 11.1166 < 0.0001
sex:strain 28 76549.1961 2733.8999 1.543 0.04
Residuals 412 729967.1062 1771.7648


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 192.0 58.2   8 20.6 0.303 136.0, 287.0 -1.43
129S1/SvImJ m 197.0 64.1   8 22.7 0.325 138.0, 295.0 -1.08
A/J f 265.0 33.5   8 11.9 0.127 216.0, 307.0 0.73
A/J m 261.0 21.1   8 7.45 0.0807 237.0, 293.0 0.5
AKR/J f 249.0 73.8   8 26.1 0.296 132.0, 391.0 0.25
AKR/J m 193.0 41.2   8 14.6 0.214 125.0, 265.0 -1.18
BALB/cByJ f 257.0 28.1   8 9.93 0.109 212.0, 289.0 0.49
BALB/cByJ m 268.0 30.5   8 10.8 0.114 211.0, 308.0 0.68
BALB/cJ f 289.0 31.2   10 9.85 0.108 252.0, 341.0 1.44
BALB/cJ m 307.0 16.2   10 5.11 0.0527 290.0, 341.0 1.64
BTBR T+ Itpr3tf/J f 300.0 55.2   8 19.5 0.184 191.0, 376.0 1.76
BTBR T+ Itpr3tf/J m 345.0 15.4   8 5.44 0.0446 317.0, 361.0 2.59
BUB/BnJ f 222.0 50.4   7 19.0 0.226 155.0, 280.0 -0.54
BUB/BnJ m 183.0 50.5   8 17.8 0.276 121.0, 274.0 -1.43
C3H/HeJ f 190.0 56.3   8 19.9 0.297 110.0, 263.0 -1.49
C3H/HeJ m 201.0 40.8   8 14.4 0.203 130.0, 256.0 -0.98
C57BL/10J f 272.0 28.3   8 9.99 0.104 243.0, 322.0 0.93
C57BL/10J m 285.0 18.2   7 6.87 0.0637 261.0, 311.0 1.1
C57BL/6J f 247.0 24.3   7 9.18 0.0985 218.0, 284.0 0.2
C57BL/6J m 244.0 33.9   13 9.4 0.139 180.0, 279.0 0.08
C57BLKS/J f 249.0 38.9   11 11.7 0.156 169.0, 294.0 0.25
C57BLKS/J m 247.0 37.1   8 13.1 0.15 182.0, 298.0 0.16
C57BR/cdJ f 282.0 29.1   6 11.9 0.103 231.0, 319.0 1.23
C57BR/cdJ m 276.0 55.2   8 19.5 0.2 198.0, 332.0 0.88
C57L/J f 262.0 32.8   8 11.6 0.125 215.0, 324.0 0.64
C57L/J m 252.0 22.3   8 7.89 0.0885 211.0, 285.0 0.28
CBA/J f 246.0 18.9   8 6.67 0.0767 217.0, 278.0 0.17
CBA/J m 233.0 29.8   8 10.6 0.128 195.0, 277.0 -0.19
CE/J f 232.0 47.2   8 16.7 0.203 138.0, 300.0 -0.25
CE/J m 231.0 59.3   9 19.8 0.256 126.0, 343.0 -0.24
DBA/1J f 212.0 31.0   10 9.8 0.146 170.0, 282.0 -0.84
DBA/1J m 270.0 43.0   8 15.2 0.16 218.0, 313.0 0.73
DBA/2J f 272.0 40.4   8 14.3 0.148 178.0, 308.0 0.93
DBA/2J m 238.0 50.3   10 15.9 0.211 164.0, 285.0 -0.06
FVB/NJ f 219.0 40.6   8 14.3 0.185 170.0, 276.0 -0.63
FVB/NJ m 248.0 49.9   7 18.9 0.201 193.0, 319.0 0.18
I/LnJ f 238.0 45.4   7 17.2 0.191 176.0, 303.0 -0.07
I/LnJ m 244.0 23.7   5 10.6 0.0971 208.0, 268.0 0.08
KK/HlJ f 208.0 28.8   8 10.2 0.138 167.0, 249.0 -0.96
KK/HlJ m 187.0 36.0   6 14.7 0.192 148.0, 252.0 -1.33
LP/J f 195.0 58.9   8 20.8 0.303 106.0, 275.0 -1.34
LP/J m 204.0 49.3   8 17.4 0.242 136.0, 265.0 -0.91
NOD/ShiLtJ f 202.0 57.3   8 20.3 0.283 154.0, 324.0 -1.13
NOD/ShiLtJ m 243.0 73.6   8 26.0 0.303 179.0, 371.0 0.06
NON/ShiLtJ f 213.0 45.6   8 16.1 0.214 133.0, 290.0 -0.81
NON/ShiLtJ m 234.0 36.9   8 13.1 0.157 193.0, 287.0 -0.16
NZW/LacJ f 236.0 30.9   8 10.9 0.131 180.0, 261.0 -0.13
NZW/LacJ m 194.0 29.3   8 10.3 0.151 151.0, 241.0 -1.15
PL/J f 235.0 27.9   8 9.86 0.119 211.0, 285.0 -0.16
PL/J m 201.0 53.3   8 18.9 0.265 144.0, 290.0 -0.98
RIIIS/J f 260.0 15.5   8 5.47 0.0596 232.0, 283.0 0.58
RIIIS/J m 265.0 48.1   8 17.0 0.181 183.0, 337.0 0.6
SJL/J f 213.0 49.6   8 17.5 0.233 147.0, 286.0 -0.81
SJL/J m 217.0 39.8   8 14.1 0.183 167.0, 276.0 -0.59
SM/J f 317.0 32.5   8 11.5 0.102 259.0, 365.0 2.26
SM/J m 310.0 47.5   8 16.8 0.153 243.0, 376.0 1.72
SWR/J f 197.0 46.4   8 16.4 0.236 151.0, 254.0 -1.28
SWR/J m 200.0 29.9   9 9.96 0.15 155.0, 244.0 -1.01


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 191.75 14.8819 221.0039 162.4961
129S1/SvImJ m 197.125 14.8819 226.3789 167.8711
A/J f 264.625 14.8819 293.8789 235.3711
A/J m 261.25 14.8819 290.5039 231.9961
AKR/J f 248.875 14.8819 278.1289 219.6211
AKR/J m 192.625 14.8819 221.8789 163.3711
BALB/cByJ f 256.625 14.8819 285.8789 227.3711
BALB/cByJ m 268.125 14.8819 297.3789 238.8711
BALB/cJ f 289.3 13.3108 315.4655 263.1345
BALB/cJ m 306.6 13.3108 332.7655 280.4345
BTBR T+ Itpr3tf/J f 300.375 14.8819 329.6289 271.1211
BTBR T+ Itpr3tf/J m 344.75 14.8819 374.0039 315.4961
BUB/BnJ f 222.4286 15.9094 253.7023 191.1548
BUB/BnJ m 183.125 14.8819 212.3789 153.8711
C3H/HeJ f 189.625 14.8819 218.8789 160.3711
C3H/HeJ m 200.625 14.8819 229.8789 171.3711
C57BL/10J f 271.875 14.8819 301.1289 242.6211
C57BL/10J m 285.2857 15.9094 316.5595 254.012
C57BL/6J f 246.5714 15.9094 277.8452 215.2977
C57BL/6J m 244.4615 11.6743 267.4102 221.5129
C57BLKS/J f 249.0 12.6913 273.9478 224.0522
C57BLKS/J m 247.125 14.8819 276.3789 217.8711
C57BR/cdJ f 281.6667 17.1841 315.4462 247.8872
C57BR/cdJ m 276.5 14.8819 305.7539 247.2461
C57L/J f 262.0 14.8819 291.2539 232.7461
C57L/J m 252.125 14.8819 281.3789 222.8711
CBA/J f 245.875 14.8819 275.1289 216.6211
CBA/J m 233.0 14.8819 262.2539 203.7461
CE/J f 232.375 14.8819 261.6289 203.1211
CE/J m 231.4444 14.0308 259.0253 203.8636
DBA/1J f 212.0 13.3108 238.1655 185.8345
DBA/1J m 269.75 14.8819 299.0039 240.4961
DBA/2J f 272.0 14.8819 301.2539 242.7461
DBA/2J m 238.0 13.3108 264.1655 211.8345
FVB/NJ f 219.0 14.8819 248.2539 189.7461
FVB/NJ m 248.1429 15.9094 279.4166 216.8691
I/LnJ f 238.0 15.9094 269.2737 206.7263
I/LnJ m 244.2 18.8243 281.2036 207.1964
KK/HlJ f 208.5 14.8819 237.7539 179.2461
KK/HlJ m 187.3333 17.1841 221.1128 153.5538
LP/J f 194.625 14.8819 223.8789 165.3711
LP/J m 203.625 14.8819 232.8789 174.3711
NOD/ShiLtJ f 202.125 14.8819 231.3789 172.8711
NOD/ShiLtJ m 242.625 14.8819 271.8789 213.3711
NON/ShiLtJ f 213.125 14.8819 242.3789 183.8711
NON/ShiLtJ m 234.5 14.8819 263.7539 205.2461
NZW/LacJ f 236.125 14.8819 265.3789 206.8711
NZW/LacJ m 193.625 14.8819 222.8789 164.3711
PL/J f 235.0 14.8819 264.2539 205.7461
PL/J m 201.125 14.8819 230.3789 171.8711
RIIIS/J f 259.625 14.8819 288.8789 230.3711
RIIIS/J m 265.25 14.8819 294.5039 235.9961
SJL/J f 212.75 14.8819 242.0039 183.4961
SJL/J m 216.875 14.8819 246.1289 187.6211
SM/J f 317.25 14.8819 346.5039 287.9961
SM/J m 309.75 14.8819 339.0039 280.4961
SWR/J f 196.625 14.8819 225.8789 167.3711
SWR/J m 199.5556 14.0308 227.1364 171.9747


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 194.4375 10.5231 215.1231 173.7519
A/J both 262.9375 10.5231 283.6231 242.2519
AKR/J both 220.75 10.5231 241.4356 200.0644
BALB/cByJ both 262.375 10.5231 283.0606 241.6894
BALB/cJ both 297.95 9.4121 316.4518 279.4482
BTBR T+ Itpr3tf/J both 322.5625 10.5231 343.2481 301.8769
BUB/BnJ both 202.7768 10.8924 224.1884 181.3651
C3H/HeJ both 195.125 10.5231 215.8106 174.4394
C57BL/10J both 278.5804 10.8924 299.992 257.1687
C57BL/6J both 245.5165 9.8666 264.9116 226.1213
C57BLKS/J both 248.0625 9.7793 267.2861 228.8389
C57BR/cdJ both 279.0833 11.3662 301.4264 256.7403
C57L/J both 257.0625 10.5231 277.7481 236.3769
CBA/J both 239.4375 10.5231 260.1231 218.7519
CE/J both 231.9097 10.2266 252.0125 211.8069
DBA/1J both 240.875 9.9831 260.4991 221.2509
DBA/2J both 255.0 9.9831 274.6241 235.3759
FVB/NJ both 233.5714 10.8924 254.9831 212.1598
I/LnJ both 241.1 12.3234 265.3245 216.8755
KK/HlJ both 197.9167 11.3662 220.2597 175.5736
LP/J both 199.125 10.5231 219.8106 178.4394
NOD/ShiLtJ both 222.375 10.5231 243.0606 201.6894
NON/ShiLtJ both 223.8125 10.5231 244.4981 203.1269
NZW/LacJ both 214.875 10.5231 235.5606 194.1894
PL/J both 218.0625 10.5231 238.7481 197.3769
RIIIS/J both 262.4375 10.5231 283.1231 241.7519
SJL/J both 214.8125 10.5231 235.4981 194.1269
SM/J both 313.5 10.5231 334.1856 292.8144
SWR/J both 198.0903 10.2266 218.1931 177.9875




  GWAS USING LINEAR MIXED MODELS