Project measure / variable:   Berndt2   breath_freq_mch10

ID, description, units MPD:35110   breath_freq_mch10   breath frequency   [n/min]  10 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - breath frequency 10 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means234   n/min 241   n/min
Median of the strain means238   n/min 236   n/min
SD of the strain means± 46.4 ± 45.7
Coefficient of variation (CV)0.198 0.190
Min–max range of strain means121   –   350   n/min 174   –   347   n/min
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4476.1744 4476.1744 2.6924 0.1016
strain 28 913869.6457 32638.2016 19.6319 < 0.0001
sex:strain 28 60053.496 2144.7677 1.2901 0.1503
Residuals 412 684952.8938 1662.507


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 200.0 36.3   8 12.8 0.181 156.0, 252.0 -0.74
129S1/SvImJ m 220.0 39.9   8 14.1 0.182 177.0, 290.0 -0.46
A/J f 238.0 40.9   8 14.5 0.172 153.0, 280.0 0.08
A/J m 236.0 47.4   8 16.8 0.201 151.0, 294.0 -0.11
AKR/J f 239.0 72.4   8 25.6 0.303 145.0, 371.0 0.1
AKR/J m 225.0 35.8   8 12.6 0.159 177.0, 266.0 -0.35
BALB/cByJ f 287.0 21.6   8 7.62 0.0751 263.0, 321.0 1.14
BALB/cByJ m 286.0 50.5   8 17.8 0.177 170.0, 329.0 0.99
BALB/cJ f 311.0 44.2   10 14.0 0.142 240.0, 363.0 1.66
BALB/cJ m 337.0 28.1   10 8.88 0.0832 287.0, 377.0 2.1
BTBR T+ Itpr3tf/J f 271.0 50.4   8 17.8 0.186 192.0, 350.0 0.79
BTBR T+ Itpr3tf/J m 257.0 50.3   8 17.8 0.196 158.0, 313.0 0.35
BUB/BnJ f 194.0 22.4   7 8.48 0.115 163.0, 231.0 -0.87
BUB/BnJ m 225.0 38.2   8 13.5 0.17 167.0, 272.0 -0.35
C3H/HeJ f 176.0 36.8   8 13.0 0.209 112.0, 211.0 -1.26
C3H/HeJ m 182.0 44.5   8 15.8 0.244 125.0, 272.0 -1.29
C57BL/10J f 260.0 23.7   8 8.38 0.0912 229.0, 295.0 0.56
C57BL/10J m 313.0 22.6   7 8.56 0.0725 277.0, 345.0 1.58
C57BL/6J f 236.0 14.2   7 5.36 0.06 216.0, 253.0 0.04
C57BL/6J m 247.0 43.0   13 11.9 0.174 194.0, 326.0 0.13
C57BLKS/J f 276.0 32.4   11 9.78 0.118 245.0, 328.0 0.9
C57BLKS/J m 292.0 70.0   8 24.8 0.24 181.0, 378.0 1.12
C57BR/cdJ f 262.0 54.5   6 22.2 0.208 196.0, 332.0 0.6
C57BR/cdJ m 273.0 38.4   8 13.6 0.141 214.0, 340.0 0.7
C57L/J f 254.0 31.7   8 11.2 0.125 202.0, 297.0 0.43
C57L/J m 283.0 38.2   8 13.5 0.135 226.0, 336.0 0.92
CBA/J f 256.0 20.7   8 7.32 0.081 219.0, 280.0 0.47
CBA/J m 239.0 19.6   8 6.94 0.0823 200.0, 268.0 -0.04
CE/J f 214.0 43.1   8 15.3 0.202 156.0, 263.0 -0.44
CE/J m 221.0 59.4   9 19.8 0.269 139.0, 294.0 -0.44
DBA/1J f 245.0 37.7   10 11.9 0.154 186.0, 306.0 0.23
DBA/1J m 236.0 38.9   8 13.8 0.165 185.0, 310.0 -0.11
DBA/2J f 266.0 31.8   8 11.2 0.12 203.0, 299.0 0.68
DBA/2J m 223.0 26.9   10 8.52 0.121 190.0, 269.0 -0.39
FVB/NJ f 232.0 25.1   8 8.87 0.108 182.0, 256.0 -0.05
FVB/NJ m 262.0 32.4   7 12.2 0.123 215.0, 313.0 0.46
I/LnJ f 224.0 55.6   7 21.0 0.249 130.0, 278.0 -0.22
I/LnJ m 208.0 38.5   5 17.2 0.185 157.0, 257.0 -0.72
KK/HlJ f 201.0 38.2   8 13.5 0.19 150.0, 268.0 -0.72
KK/HlJ m 221.0 60.3   6 24.6 0.273 149.0, 331.0 -0.44
LP/J f 195.0 31.9   8 11.3 0.163 158.0, 241.0 -0.85
LP/J m 208.0 50.6   8 17.9 0.244 164.0, 327.0 -0.72
NOD/ShiLtJ f 238.0 37.8   8 13.3 0.158 188.0, 292.0 0.08
NOD/ShiLtJ m 275.0 49.0   8 17.3 0.178 220.0, 351.0 0.75
NON/ShiLtJ f 121.0 22.1   8 7.83 0.184 94.1, 151.0 -2.44
NON/ShiLtJ m 174.0 58.0   8 20.5 0.334 110.0, 271.0 -1.47
NZW/LacJ f 214.0 33.6   8 11.9 0.157 156.0, 268.0 -0.44
NZW/LacJ m 196.0 44.2   8 15.6 0.225 144.0, 273.0 -0.98
PL/J f 163.0 48.1   8 17.0 0.296 103.0, 224.0 -1.54
PL/J m 177.0 34.8   8 12.3 0.196 130.0, 244.0 -1.4
RIIIS/J f 271.0 26.0   8 9.21 0.0962 244.0, 327.0 0.79
RIIIS/J m 241.0 45.1   8 15.9 0.187 186.0, 311.0 0.0
SJL/J f 208.0 40.0   8 14.2 0.193 159.0, 276.0 -0.57
SJL/J m 195.0 36.1   8 12.8 0.186 158.0, 253.0 -1.01
SM/J f 350.0 32.1   8 11.4 0.0919 303.0, 385.0 2.5
SM/J m 347.0 32.2   8 11.4 0.0928 308.0, 398.0 2.32
SWR/J f 191.0 46.9   8 16.6 0.245 134.0, 253.0 -0.93
SWR/J m 187.0 41.9   9 14.0 0.224 139.0, 273.0 -1.18


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 200.5 14.4157 228.8376 172.1624
129S1/SvImJ m 219.75 14.4157 248.0876 191.4124
A/J f 238.125 14.4157 266.4626 209.7874
A/J m 236.375 14.4157 264.7126 208.0374
AKR/J f 239.0 14.4157 267.3376 210.6624
AKR/J m 225.25 14.4157 253.5876 196.9124
BALB/cByJ f 287.25 14.4157 315.5876 258.9124
BALB/cByJ m 285.5 14.4157 313.8376 257.1624
BALB/cJ f 310.7 12.8938 336.0459 285.3541
BALB/cJ m 337.3 12.8938 362.6459 311.9541
BTBR T+ Itpr3tf/J f 271.0 14.4157 299.3376 242.6624
BTBR T+ Itpr3tf/J m 257.125 14.4157 285.4626 228.7874
BUB/BnJ f 194.4286 15.4111 224.7227 164.1344
BUB/BnJ m 224.75 14.4157 253.0876 196.4124
C3H/HeJ f 175.875 14.4157 204.2126 147.5374
C3H/HeJ m 182.375 14.4157 210.7126 154.0374
C57BL/10J f 260.0 14.4157 288.3376 231.6624
C57BL/10J m 312.5714 15.4111 342.8656 282.2773
C57BL/6J f 236.2857 15.4111 266.5798 205.9916
C57BL/6J m 247.3077 11.3086 269.5375 225.0779
C57BLKS/J f 275.7273 12.2938 299.8936 251.5609
C57BLKS/J m 292.0 14.4157 320.3376 263.6624
C57BR/cdJ f 262.0 16.6459 294.7214 229.2786
C57BR/cdJ m 273.0 14.4157 301.3376 244.6624
C57L/J f 253.625 14.4157 281.9626 225.2874
C57L/J m 283.0 14.4157 311.3376 254.6624
CBA/J f 255.5 14.4157 283.8376 227.1624
CBA/J m 238.625 14.4157 266.9626 210.2874
CE/J f 213.5 14.4157 241.8376 185.1624
CE/J m 220.7778 13.5913 247.4947 194.0609
DBA/1J f 245.0 12.8938 270.3459 219.6541
DBA/1J m 236.375 14.4157 264.7126 208.0374
DBA/2J f 265.625 14.4157 293.9626 237.2874
DBA/2J m 223.0 12.8938 248.3459 197.6541
FVB/NJ f 231.5 14.4157 259.8376 203.1624
FVB/NJ m 262.4286 15.4111 292.7227 232.1344
I/LnJ f 223.7143 15.4111 254.0084 193.4202
I/LnJ m 207.6 18.2346 243.4445 171.7555
KK/HlJ f 200.75 14.4157 229.0876 172.4124
KK/HlJ m 220.8333 16.6459 253.5547 188.1119
LP/J f 195.125 14.4157 223.4626 166.7874
LP/J m 207.5 14.4157 235.8376 179.1624
NOD/ShiLtJ f 238.375 14.4157 266.7126 210.0374
NOD/ShiLtJ m 275.25 14.4157 303.5876 246.9124
NON/ShiLtJ f 120.7 14.4157 149.0376 92.3624
NON/ShiLtJ m 173.625 14.4157 201.9626 145.2874
NZW/LacJ f 213.625 14.4157 241.9626 185.2874
NZW/LacJ m 196.25 14.4157 224.5876 167.9124
PL/J f 162.875 14.4157 191.2126 134.5374
PL/J m 177.25 14.4157 205.5876 148.9124
RIIIS/J f 270.625 14.4157 298.9626 242.2874
RIIIS/J m 241.125 14.4157 269.4626 212.7874
SJL/J f 207.5 14.4157 235.8376 179.1624
SJL/J m 194.75 14.4157 223.0876 166.4124
SM/J f 349.625 14.4157 377.9626 321.2874
SM/J m 346.625 14.4157 374.9626 318.2874
SWR/J f 191.375 14.4157 219.7126 163.0374
SWR/J m 186.8889 13.5913 213.6058 160.172


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 210.125 10.1935 230.1627 190.0873
A/J both 237.25 10.1935 257.2877 217.2123
AKR/J both 232.125 10.1935 252.1627 212.0873
BALB/cByJ both 286.375 10.1935 306.4127 266.3373
BALB/cJ both 324.0 9.1173 341.9222 306.0778
BTBR T+ Itpr3tf/J both 264.0625 10.1935 284.1002 244.0248
BUB/BnJ both 209.5893 10.5512 230.3303 188.8483
C3H/HeJ both 179.125 10.1935 199.1627 159.0873
C57BL/10J both 286.2857 10.5512 307.0267 265.5447
C57BL/6J both 241.7967 9.5575 260.5843 223.0091
C57BLKS/J both 283.8636 9.473 302.4851 265.2422
C57BR/cdJ both 267.5 11.0102 289.1432 245.8568
C57L/J both 268.3125 10.1935 288.3502 248.2748
CBA/J both 247.0625 10.1935 267.1002 227.0248
CE/J both 217.1389 9.9063 236.612 197.6658
DBA/1J both 240.6875 9.6704 259.6969 221.6781
DBA/2J both 244.3125 9.6704 263.3219 225.3031
FVB/NJ both 246.9643 10.5512 267.7053 226.2233
I/LnJ both 215.6571 11.9374 239.1229 192.1914
KK/HlJ both 210.7917 11.0102 232.4348 189.1485
LP/J both 201.3125 10.1935 221.3502 181.2748
NOD/ShiLtJ both 256.8125 10.1935 276.8502 236.7748
NON/ShiLtJ both 147.1625 10.1935 167.2002 127.1248
NZW/LacJ both 204.9375 10.1935 224.9752 184.8998
PL/J both 170.0625 10.1935 190.1002 150.0248
RIIIS/J both 255.875 10.1935 275.9127 235.8373
SJL/J both 201.125 10.1935 221.1627 181.0873
SM/J both 348.125 10.1935 368.1627 328.0873
SWR/J both 189.1319 9.9063 208.6051 169.6588




  GWAS USING LINEAR MIXED MODELS