Project measure / variable:   Berndt2   breath_freq_saline

ID, description, units MPD:35108   breath_freq_saline   breath frequency   [n/min]  saline  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - breath frequency saline



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means240   n/min 244   n/min
Median of the strain means233   n/min 238   n/min
SD of the strain means± 35.1 ± 37.5
Coefficient of variation (CV)0.146 0.153
Min–max range of strain means184   –   321   n/min 164   –   313   n/min
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2975.1843 2975.1843 1.4274 0.2329
strain 28 533488.5302 19053.1618 9.1414 < 0.0001
sex:strain 28 70002.1107 2500.0754 1.1995 0.2251
Residuals 412 858718.5493 2084.2683


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 220.0 50.6   8 17.9 0.23 138.0, 288.0 -0.57
129S1/SvImJ m 238.0 48.5   8 17.1 0.204 161.0, 286.0 -0.17
A/J f 254.0 33.8   8 12.0 0.133 217.0, 324.0 0.4
A/J m 270.0 29.8   8 10.5 0.11 224.0, 317.0 0.69
AKR/J f 232.0 71.4   8 25.2 0.307 131.0, 370.0 -0.22
AKR/J m 188.0 48.6   8 17.2 0.258 138.0, 262.0 -1.5
BALB/cByJ f 246.0 36.2   8 12.8 0.147 186.0, 292.0 0.17
BALB/cByJ m 274.0 37.2   8 13.2 0.136 233.0, 324.0 0.8
BALB/cJ f 288.0 67.1   10 21.2 0.233 200.0, 414.0 1.37
BALB/cJ m 299.0 48.8   10 15.4 0.163 200.0, 368.0 1.46
BTBR T+ Itpr3tf/J f 283.0 54.8   8 19.4 0.194 178.0, 363.0 1.23
BTBR T+ Itpr3tf/J m 313.0 35.6   8 12.6 0.114 254.0, 361.0 1.84
BUB/BnJ f 228.0 69.1   7 26.1 0.303 150.0, 342.0 -0.34
BUB/BnJ m 214.0 46.3   8 16.4 0.216 161.0, 282.0 -0.81
C3H/HeJ f 218.0 36.6   8 12.9 0.168 156.0, 279.0 -0.62
C3H/HeJ m 191.0 39.7   8 14.0 0.208 146.0, 247.0 -1.42
C57BL/10J f 268.0 47.3   8 16.7 0.177 235.0, 383.0 0.8
C57BL/10J m 303.0 23.6   7 8.94 0.0781 278.0, 339.0 1.57
C57BL/6J f 262.0 46.1   7 17.4 0.176 208.0, 334.0 0.63
C57BL/6J m 270.0 53.2   13 14.7 0.197 207.0, 355.0 0.69
C57BLKS/J f 264.0 59.4   11 17.9 0.225 176.0, 351.0 0.69
C57BLKS/J m 244.0 28.0   8 9.9 0.115 199.0, 280.0 -0.01
C57BR/cdJ f 273.0 69.4   6 28.4 0.254 181.0, 370.0 0.94
C57BR/cdJ m 287.0 27.6   8 9.77 0.0963 231.0, 323.0 1.14
C57L/J f 248.0 40.0   8 14.1 0.161 207.0, 310.0 0.23
C57L/J m 236.0 30.3   8 10.7 0.129 192.0, 278.0 -0.22
CBA/J f 208.0 43.5   8 15.4 0.209 163.0, 277.0 -0.91
CBA/J m 220.0 44.9   8 15.9 0.204 160.0, 288.0 -0.65
CE/J f 283.0 55.1   8 19.5 0.195 160.0, 334.0 1.23
CE/J m 260.0 37.3   9 12.4 0.144 206.0, 314.0 0.42
DBA/1J f 216.0 46.9   10 14.8 0.217 161.0, 303.0 -0.68
DBA/1J m 219.0 55.8   8 19.7 0.254 149.0, 286.0 -0.67
DBA/2J f 261.0 41.9   8 14.8 0.161 201.0, 313.0 0.6
DBA/2J m 263.0 34.5   10 10.9 0.131 219.0, 314.0 0.5
FVB/NJ f 207.0 61.1   8 21.6 0.296 148.0, 323.0 -0.94
FVB/NJ m 233.0 45.3   7 17.1 0.194 165.0, 283.0 -0.3
I/LnJ f 212.0 36.4   7 13.8 0.172 160.0, 259.0 -0.79
I/LnJ m 239.0 22.1   5 9.86 0.0923 212.0, 265.0 -0.14
KK/HlJ f 223.0 42.7   8 15.1 0.191 167.0, 302.0 -0.48
KK/HlJ m 230.0 31.2   6 12.7 0.136 206.0, 290.0 -0.38
LP/J f 191.0 47.4   8 16.8 0.248 111.0, 258.0 -1.39
LP/J m 232.0 50.9   8 18.0 0.22 171.0, 308.0 -0.33
NOD/ShiLtJ f 193.0 38.8   8 13.7 0.201 137.0, 260.0 -1.34
NOD/ShiLtJ m 209.0 43.0   8 15.2 0.206 155.0, 290.0 -0.94
NON/ShiLtJ f 207.0 56.7   8 20.1 0.274 117.0, 277.0 -0.94
NON/ShiLtJ m 276.0 33.6   8 11.9 0.121 240.0, 346.0 0.85
NZW/LacJ f 184.0 48.7   8 17.2 0.265 131.0, 250.0 -1.59
NZW/LacJ m 164.0 18.0   8 6.35 0.11 145.0, 187.0 -2.14
PL/J f 239.0 61.1   8 21.6 0.255 155.0, 356.0 -0.02
PL/J m 223.0 66.5   8 23.5 0.298 175.0, 374.0 -0.57
RIIIS/J f 294.0 50.0   8 17.7 0.17 241.0, 370.0 1.54
RIIIS/J m 272.0 39.7   8 14.0 0.146 184.0, 308.0 0.74
SJL/J f 233.0 25.9   8 9.15 0.111 178.0, 268.0 -0.2
SJL/J m 222.0 38.8   8 13.7 0.174 183.0, 271.0 -0.59
SM/J f 321.0 25.8   8 9.14 0.0805 288.0, 355.0 2.31
SM/J m 293.0 34.1   8 12.1 0.117 248.0, 354.0 1.3
SWR/J f 200.0 41.5   8 14.7 0.208 137.0, 261.0 -1.14
SWR/J m 200.0 29.5   9 9.85 0.148 155.0, 246.0 -1.18


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 220.5 16.1411 252.2291 188.7709
129S1/SvImJ m 237.75 16.1411 269.4791 206.0209
A/J f 254.25 16.1411 285.9791 222.5209
A/J m 270.0 16.1411 301.7291 238.2709
AKR/J f 232.5 16.1411 264.2291 200.7709
AKR/J m 188.375 16.1411 220.1041 156.6459
BALB/cByJ f 245.625 16.1411 277.3541 213.8959
BALB/cByJ m 274.375 16.1411 306.1041 242.6459
BALB/cJ f 288.3 14.437 316.6794 259.9206
BALB/cJ m 299.0 14.437 327.3794 270.6206
BTBR T+ Itpr3tf/J f 283.125 16.1411 314.8541 251.3959
BTBR T+ Itpr3tf/J m 313.375 16.1411 345.1041 281.6459
BUB/BnJ f 228.2857 17.2555 262.2055 194.3659
BUB/BnJ m 213.75 16.1411 245.4791 182.0209
C3H/HeJ f 217.625 16.1411 249.3541 185.8959
C3H/HeJ m 190.75 16.1411 222.4791 159.0209
C57BL/10J f 267.625 16.1411 299.3541 235.8959
C57BL/10J m 302.8571 17.2555 336.777 268.9373
C57BL/6J f 261.8571 17.2555 295.777 227.9373
C57BL/6J m 269.9231 12.6621 294.8134 245.0327
C57BLKS/J f 264.2727 13.7651 291.3314 237.2141
C57BLKS/J m 244.375 16.1411 276.1041 212.6459
C57BR/cdJ f 273.3333 18.6381 309.9709 236.6957
C57BR/cdJ m 287.0 16.1411 318.7291 255.2709
C57L/J f 248.5 16.1411 280.2291 216.7709
C57L/J m 235.75 16.1411 267.4791 204.0209
CBA/J f 208.375 16.1411 240.1041 176.6459
CBA/J m 219.625 16.1411 251.3541 187.8959
CE/J f 282.75 16.1411 314.4791 251.0209
CE/J m 260.2222 15.2179 290.1367 230.3078
DBA/1J f 215.9 14.437 244.2794 187.5206
DBA/1J m 219.25 16.1411 250.9791 187.5209
DBA/2J f 260.75 16.1411 292.4791 229.0209
DBA/2J m 263.0 14.437 291.3794 234.6206
FVB/NJ f 206.75 16.1411 238.4791 175.0209
FVB/NJ m 232.8571 17.2555 266.777 198.9373
I/LnJ f 212.0 17.2555 245.9198 178.0802
I/LnJ m 239.0 20.417 279.1345 198.8655
KK/HlJ f 223.25 16.1411 254.9791 191.5209
KK/HlJ m 230.0 18.6381 266.6376 193.3624
LP/J f 190.875 16.1411 222.6041 159.1459
LP/J m 231.625 16.1411 263.3541 199.8959
NOD/ShiLtJ f 193.25 16.1411 224.9791 161.5209
NOD/ShiLtJ m 208.875 16.1411 240.6041 177.1459
NON/ShiLtJ f 207.375 16.1411 239.1041 175.6459
NON/ShiLtJ m 276.5 16.1411 308.2291 244.7709
NZW/LacJ f 183.5 16.1411 215.2291 151.7709
NZW/LacJ m 163.625 16.1411 195.3541 131.8959
PL/J f 239.25 16.1411 270.9791 207.5209
PL/J m 223.375 16.1411 255.1041 191.6459
RIIIS/J f 294.25 16.1411 325.9791 262.5209
RIIIS/J m 271.75 16.1411 303.4791 240.0209
SJL/J f 232.625 16.1411 264.3541 200.8959
SJL/J m 222.25 16.1411 253.9791 190.5209
SM/J f 320.875 16.1411 352.6041 289.1459
SM/J m 292.875 16.1411 324.6041 261.1459
SWR/J f 199.875 16.1411 231.6041 168.1459
SWR/J m 200.2222 15.2179 230.1367 170.3078


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 229.125 11.4134 251.5609 206.6891
A/J both 262.125 11.4134 284.5609 239.6891
AKR/J both 210.4375 11.4134 232.8734 188.0016
BALB/cByJ both 260.0 11.4134 282.4359 237.5641
BALB/cJ both 293.65 10.2085 313.7172 273.5828
BTBR T+ Itpr3tf/J both 298.25 11.4134 320.6859 275.8141
BUB/BnJ both 221.0179 11.814 244.2412 197.7945
C3H/HeJ both 204.1875 11.4134 226.6234 181.7516
C57BL/10J both 285.2411 11.814 308.4644 262.0178
C57BL/6J both 265.8901 10.7014 286.9263 244.8539
C57BLKS/J both 254.3239 10.6067 275.174 233.4738
C57BR/cdJ both 280.1667 12.3279 304.4002 255.9332
C57L/J both 242.125 11.4134 264.5609 219.6891
CBA/J both 214.0 11.4134 236.4359 191.5641
CE/J both 271.4861 11.0919 293.2898 249.6824
DBA/1J both 217.575 10.8277 238.8595 196.2905
DBA/2J both 261.875 10.8277 283.1595 240.5905
FVB/NJ both 219.8036 11.814 243.0269 196.5803
I/LnJ both 225.5 13.3661 251.7742 199.2258
KK/HlJ both 226.625 12.3279 250.8585 202.3915
LP/J both 211.25 11.4134 233.6859 188.8141
NOD/ShiLtJ both 201.0625 11.4134 223.4984 178.6266
NON/ShiLtJ both 241.9375 11.4134 264.3734 219.5016
NZW/LacJ both 173.5625 11.4134 195.9984 151.1266
PL/J both 231.3125 11.4134 253.7484 208.8766
RIIIS/J both 283.0 11.4134 305.4359 260.5641
SJL/J both 227.4375 11.4134 249.8734 205.0016
SM/J both 306.875 11.4134 329.3109 284.4391
SWR/J both 200.0486 11.0919 221.8523 178.2449




  GWAS USING LINEAR MIXED MODELS