Project measure / variable:   Shockley1   CHOL_fat

ID, description, units MPD:33436   CHOL_fat   total cholesterol (CHOL)   [mg/dL]  high-fat diet  
high-fat diet study
Data set, strains Shockley1   inbred   10 strains     sex: both     age: 10-13wks
Procedure lipid profile
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  STRAIN COMPARISON PLOT
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Shockley1 - total cholesterol (CHOL) high-fat diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means216   mg/dL 221   mg/dL
Median of the strain means196   mg/dL 220   mg/dL
SD of the strain means± 71.3 ± 47.9
Coefficient of variation (CV)0.329 0.217
Min–max range of strain means155   –   374   mg/dL 132   –   319   mg/dL
Mean sample size per strain4.8   mice 4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 86.7326 86.7326 0.0879 0.7676
strain 9 271915.7724 30212.8636 30.6361 < 0.0001
sex:strain 9 39618.5612 4402.0624 4.4637 0.0001
Residuals 73 71991.45 986.1842


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 290.0 63.7   4 31.8 0.22 231.0, 377.0 1.03
129S1/SvImJ m 241.0 28.8   5 12.9 0.119 214.0, 282.0 0.42
A/J f 218.0 48.5   4 24.3 0.223 186.0, 290.0 0.02
A/J m 205.0 28.3   5 12.7 0.138 183.0, 252.0 -0.33
BALB/cJ f 175.0 17.0   5 7.58 0.0969 158.0, 199.0 -0.58
BALB/cJ m 132.0 21.6   5 9.67 0.163 103.0, 155.0 -1.85
C3H/HeJ f 242.0 30.8   5 13.8 0.127 191.0, 273.0 0.36
C3H/HeJ m 234.0 8.49   2   6.0 0.0363 228.0, 240.0 0.28
C57BL/6J f 157.0 17.3   5 7.73 0.11 132.0, 174.0 -0.83
C57BL/6J m 191.0 10.5   5 4.71 0.055 178.0, 202.0 -0.62
DBA/2J f 155.0 13.5   5 6.04 0.0872 137.0, 174.0 -0.86
DBA/2J m 197.0 21.1   5 9.43 0.107 166.0, 217.0 -0.49
I/LnJ f 156.0 42.8   4 21.4 0.274 111.0, 203.0 -0.85
I/LnJ m 213.0 13.9   5 6.24 0.0655 200.0, 235.0 -0.16
MRL/MpJ-Faslpr/J f 225.0 20.2   5 9.04 0.0899 194.0, 245.0 0.12
MRL/MpJ-Faslpr/J m 248.0 12.0   5 5.36 0.0483 228.0, 258.0 0.57
NZB/BlNJ f 374.0 39.6   5 17.7 0.106 340.0, 440.0 2.21
NZB/BlNJ m 319.0 30.2   4 15.1 0.0945 282.0, 353.0 2.05
SM/J f 171.0 31.3   5 14.0 0.183 118.0, 196.0 -0.64
SM/J m 227.0 58.8   5 26.3 0.259 189.0, 329.0 0.13


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 289.75 15.7018 321.0436 258.4564
129S1/SvImJ m 241.4 14.0441 269.3899 213.4101
A/J f 217.75 15.7018 249.0436 186.4564
A/J m 204.8 14.0441 232.7899 176.8101
BALB/cJ f 175.0 14.0441 202.9899 147.0101
BALB/cJ m 132.4 14.0441 160.3899 104.4101
C3H/HeJ f 241.6 14.0441 269.5899 213.6101
C3H/HeJ m 234.0 22.2057 278.2559 189.7441
C57BL/6J f 156.8 14.0441 184.7899 128.8101
C57BL/6J m 191.2 14.0441 219.1899 163.2101
DBA/2J f 155.0 14.0441 182.9899 127.0101
DBA/2J m 196.8 14.0441 224.7899 168.8101
I/LnJ f 156.0 15.7018 187.2936 124.7064
I/LnJ m 213.0 14.0441 240.9899 185.0101
MRL/MpJ-Faslpr/J f 224.8 14.0441 252.7899 196.8101
MRL/MpJ-Faslpr/J m 248.0 14.0441 275.9899 220.0101
NZB/BlNJ f 373.8 14.0441 401.7899 345.8101
NZB/BlNJ m 319.25 15.7018 350.5436 287.9564
SM/J f 171.2 14.0441 199.1899 143.2101
SM/J m 227.0 14.0441 254.9899 199.0101


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 265.575 10.5331 286.5674 244.5826
A/J both 211.275 10.5331 232.2674 190.2826
BALB/cJ both 153.7 9.9307 173.4918 133.9082
C3H/HeJ both 237.8 13.1371 263.9821 211.6179
C57BL/6J both 174.0 9.9307 193.7918 154.2082
DBA/2J both 175.9 9.9307 195.6918 156.1082
I/LnJ both 184.5 10.5331 205.4924 163.5076
MRL/MpJ-Faslpr/J both 236.4 9.9307 256.1918 216.6082
NZB/BlNJ both 346.525 10.5331 367.5174 325.5326
SM/J both 199.1 9.9307 218.8918 179.3082




  GWAS USING LINEAR MIXED MODELS