Project measure / variable:   Threadgill1   AST_ctrl

ID, description, units MPD:19410   AST_ctrl   aspartate transaminase (serum AST)   [IU/L]  control  
acetaminophen study
Data set, strains Threadgill1   inbred w/CC7   37 strains     sex: m     age: 8-17wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Threadgill1 - aspartate transaminase (serum AST) control



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested37 strains
Mean of the strain means190   IU/L
Median of the strain means116   IU/L
SD of the strain means± 331
Coefficient of variation (CV)1.74
Min–max range of strain means60.0   –   2070   IU/L
Mean sample size per strain2.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 645251.0 19553.0606 0.865 0.6624
Residuals 38 858959.0 22604.1842


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 117.0 46.7   2   33.0 0.399 84.0, 150.0 -0.22
A/J m 134.0 50.2   2   35.5 0.373 99.0, 170.0 -0.17
AKR/J m 60.0 25.5   2   18.0 0.424 42.0, 78.0 -0.39
B6C3F1/J m 90.0 12.7   2   9.0 0.141 81.0, 99.0 -0.3
BALB/cByJ m 128.0 45.3   2   32.0 0.354 96.0, 160.0 -0.19
BTBR T+ Itpr3tf/J m 80.0 14.1   2   10.0 0.177 70.0, 90.0 -0.33
BUB/BnJ m 92.0 36.3   3 21.0 0.394 51.0, 120.0 -0.3
C3H/HeJ m 108.0 44.5   2   31.5 0.411 77.0, 140.0 -0.25
C57BL/10J m 112.0 53.7   2   38.0 0.48 74.0, 150.0 -0.24
C57BL/6J m 116.0 90.5   2   64.0 0.78 52.0, 180.0 -0.22
C57BLKS/J m 91.5 2.12   2   1.5 0.0232 90.0, 93.0 -0.3
C57BR/cdJ m 186.0 65.1   2   46.0 0.35 140.0, 232.0 -0.01
C57L/J m 156.0 111.0   2   78.5 0.709 78.0, 235.0 -0.1
CAST/EiJ m 170.0 0.0   1   0.0 0.0 170.0, 170.0 -0.06
CBA/J m 120.0 28.3   2   20.0 0.236 100.0, 140.0 -0.21
CZECHII/EiJ m 150.0 31.1   3 17.9 0.207 129.0, 186.0 -0.12
DBA/2J m 120.0 42.4   2   30.0 0.354 90.0, 150.0 -0.21
FVB/NJ m 95.0 63.6   2   45.0 0.67 50.0, 140.0 -0.29
JF1/MsJ m 122.0 14.8   2   10.5 0.121 112.0, 133.0 -0.21
KK/HlJ m 95.0 7.07   2   5.0 0.0744 90.0, 100.0 -0.29
LP/J m 108.0 45.3   2   32.0 0.419 76.0, 140.0 -0.25
MA/MyJ m 202.0 96.9   2   68.5 0.481 133.0, 270.0 0.04
MSM/MsJ m 117.0 18.4   2   13.0 0.157 104.0, 130.0 -0.22
NOD/ShiLtJ m 95.0 4.24   2   3.0 0.0447 92.0, 98.0 -0.29
NON/ShiLtJ m 126.0 2.12   2   1.5 0.0168 125.0, 128.0 -0.19
NZO/HlLtJ m 433.0 474.0   2   335.0 1.09 98.0, 768.0 0.73
NZW/LacJ m 98.0 45.3   2   32.0 0.462 66.0, 130.0 -0.28
PERA/EiJ m 114.0 49.7   3 28.7 0.437 76.0, 170.0 -0.23
P/J m 120.0 13.4   2   9.5 0.111 111.0, 130.0 -0.21
PL/J m 95.5 6.36   2   4.5 0.0666 91.0, 100.0 -0.28
PWD/PhJ m 130.0 36.8   2   26.0 0.283 104.0, 156.0 -0.18
RIIIS/J m 100.0 0.0   1   0.0 0.0 100.0, 100.0 -0.27
SEA/GnJ m 2070.0 0.0   1   0.0 0.0 2070.0, 2070.0 5.67
SJL/J m 98.0 5.66   2   4.0 0.0577 94.0, 102.0 -0.28
SM/J m 114.0 58.7   2   41.5 0.517 72.0, 155.0 -0.23
SWR/J m 90.7 2.08   3 1.2 0.023 89.0, 93.0 -0.3
WSB/EiJ m 575.0 750.0   2   530.0 1.3 45.0, 1105.0 1.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 117.0 106.3113 332.216 0.0
A/J m 134.5 106.3113 349.716 0.0
AKR/J m 60.0 106.3113 275.216 0.0
B6C3F1/J m 90.0 106.3113 305.216 0.0
BALB/cByJ m 128.0 106.3113 343.216 0.0
BTBR T+ Itpr3tf/J m 80.0 106.3113 295.216 0.0
BUB/BnJ m 92.0 86.8028 267.7231 0.0
C3H/HeJ m 108.5 106.3113 323.716 0.0
C57BL/10J m 112.0 106.3113 327.216 0.0
C57BL/6J m 116.0 106.3113 331.216 0.0
C57BLKS/J m 91.5 106.3113 306.716 0.0
C57BR/cdJ m 186.0 106.3113 401.216 0.0
C57L/J m 156.5 106.3113 371.716 0.0
CBA/J m 120.0 106.3113 335.216 0.0
CZECHII/EiJ m 150.3333 86.8028 326.0564 0.0
DBA/2J m 120.0 106.3113 335.216 0.0
FVB/NJ m 95.0 106.3113 310.216 0.0
JF1/MsJ m 122.5 106.3113 337.716 0.0
KK/HlJ m 95.0 106.3113 310.216 0.0
LP/J m 108.0 106.3113 323.216 0.0
MA/MyJ m 201.5 106.3113 416.716 0.0
MSM/MsJ m 117.0 106.3113 332.216 0.0
NOD/ShiLtJ m 95.0 106.3113 310.216 0.0
NON/ShiLtJ m 126.5 106.3113 341.716 0.0
NZO/HlLtJ m 433.0 106.3113 648.216 217.784
NZW/LacJ m 98.0 106.3113 313.216 0.0
PERA/EiJ m 113.6667 86.8028 289.3898 0.0
P/J m 120.5 106.3113 335.716 0.0
PL/J m 95.5 106.3113 310.716 0.0
PWD/PhJ m 130.0 106.3113 345.216 0.0
SJL/J m 98.0 106.3113 313.216 0.0
SM/J m 113.5 106.3113 328.716 0.0
SWR/J m 90.6667 86.8028 266.3898 0.0
WSB/EiJ m 575.0 106.3113 790.216 359.784




  GWAS USING LINEAR MIXED MODELS