MPD: QTL phenotype measures: diabetes

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	Sex	Age	Sample Size (Avg)	Year
Attie1:1	Attie1	eQTL	(none)	eQTL investigation of obesity and diabetes ob_diab 53201	QTL population	both	10wks	N=272	2015

Leiter2:1	Leiter2	health assessment	(none)	age of diabetes onset (dash = no diabetes) [wks] Onset 24001	QTL population	f	14-40wks	N=310	2009

Leiter2:2	Leiter2	health assessment	(none)	1 = diabetes, 0 = no diabetes [score] DB1_0 24002	QTL population	f	14-40wks	N=310	2009

Leiter2:3	Leiter2	histopathology	(none)	combination score of age at type 1 diabetes onset, and insulitis severity / extent (see excel file) [score] Insulities_TimeOnset 24003	QTL population	f	14-40wks	N=310	2009

Leiter2:4	Leiter2	histopathology	(none)	insulitis severity / extent score (0-4, see excel file) [score] Insulitis 24004	QTL population	f	14-40wks	N=310	2009

Leiter2:5	Leiter2	histopathology	(none)	group mice by insulitis score (0-3, see excel file) [score] GroupInsulitis_Diabetes 24005	QTL population	f	14-40wks	N=310	2009

Leiter2:6	Leiter2	body weight	(none)	body weight at 30 wks of age (if alive, mice were sacrificed when determined to be diabetic 2 wks in a row) [g] 30wk 24006	QTL population	f	30wks	N=310	2009

Leiter2:7	Leiter2	body weight	(none)	body weight at 40 wks of age (if alive, mice were sacrificed when determined to be diabetic 2 wks in a row) [g] 40wk 24007	QTL population	f	40wks	N=310	2009

Mathews1:1	Mathews1	histopathology	(none)	Clinical T1DM accompanied by end-stage insulitis before necropsy (score 0=non-diabetes, 1=diabetes) [score] IDDM 13401	QTL population	f	8-40wks	N=120	2003

Mathews1:2	Mathews1	histopathology	(none)	severity of diabetes (score 0=non-diabetes, 1=diabetes, 2=severe diabetes) [score] IDDM_VS_HI 13402	QTL population	f	8-40wks	N=120	2003

Mathews1:3	Mathews1	histopathology	(none)	Clinical T1DM accompanied by end-stage insulitis diagnosed at necropsy (score 0=non-diabetes, 1=diabetes) [score] IDM 13403	QTL population	f	8-40wks	N=120	2003

Reifsnyder2:1	Reifsnyder2	histopathology	(none)	the week of clinical diabetes onset [n] Onset 17601	QTL population	f	12-40wks	N=185	2005

Reifsnyder2:2	Reifsnyder2	histopathology	(none)	insulitis score of diabetes-free mice, (from 0.002=virtually no insulitis, to 1.0=incipient diabetic) Insulitis_Index 17602	QTL population	f	12-40wks	N=185	2005

Reifsnyder2:3	Reifsnyder2	histopathology	(none)	first principal component of age at diabetes onset and severity/extent of insulitis Prin1 17603	QTL population	f	12-40wks	N=185	2005

Reifsnyder2:4	Reifsnyder2	histopathology	(none)	second principal component of age at diabetes onset and severity / extent of insulitis Prin2 17604	QTL population	f	12-40wks	N=185	2005

Attie1

eQTL

(none)

eQTL investigation of obesity and diabetes ob_diab 53201

QTL population

both

10wks

N=272

2015

Leiter2

health assessment

(none)

age of diabetes onset (dash = no diabetes) [wks] Onset 24001

QTL population

f

14-40wks

N=310

2009

Leiter2

health assessment

(none)

1 = diabetes, 0 = no diabetes [score] DB1_0 24002

QTL population

f

14-40wks

N=310

2009

Leiter2

histopathology

(none)

combination score of age at type 1 diabetes onset, and insulitis severity / extent (see excel file) [score] Insulities_TimeOnset 24003

QTL population

f

14-40wks

N=310

2009

Leiter2

histopathology

(none)

insulitis severity / extent score (0-4, see excel file) [score] Insulitis 24004

QTL population

f

14-40wks

N=310

2009

Leiter2

histopathology

(none)

group mice by insulitis score (0-3, see excel file) [score] GroupInsulitis_Diabetes 24005

QTL population

f

14-40wks

N=310

2009

Leiter2

body weight

(none)

body weight at 30 wks of age (if alive, mice were sacrificed when determined to be diabetic 2 wks in a row) [g] 30wk 24006

QTL population

f

30wks

N=310

2009

Leiter2

body weight

(none)

body weight at 40 wks of age (if alive, mice were sacrificed when determined to be diabetic 2 wks in a row) [g] 40wk 24007

QTL population

f

40wks

N=310

2009

Mathews1

histopathology

(none)

Clinical T1DM accompanied by end-stage insulitis before necropsy (score 0=non-diabetes, 1=diabetes) [score] IDDM 13401

QTL population

f

8-40wks

N=120

2003

Mathews1

histopathology

(none)

severity of diabetes (score 0=non-diabetes, 1=diabetes, 2=severe diabetes) [score] IDDM_VS_HI 13402

QTL population

f

8-40wks

N=120

2003

Mathews1

histopathology

(none)

Clinical T1DM accompanied by end-stage insulitis diagnosed at necropsy (score 0=non-diabetes, 1=diabetes) [score] IDM 13403

QTL population

f

8-40wks

N=120

2003

Reifsnyder2

histopathology

(none)

the week of clinical diabetes onset [n] Onset 17601

QTL population

f

12-40wks

N=185

2005

Reifsnyder2

histopathology

(none)

insulitis score of diabetes-free mice, (from 0.002=virtually no insulitis, to 1.0=incipient diabetic) Insulitis_Index 17602

QTL population

f

12-40wks

N=185

2005

Reifsnyder2

histopathology

(none)

first principal component of age at diabetes onset and severity/extent of insulitis Prin1 17603

QTL population

f

12-40wks

N=185

2005

Reifsnyder2

histopathology

(none)

second principal component of age at diabetes onset and severity / extent of insulitis Prin2 17604

QTL population

f

12-40wks

N=185

2005

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