Project measure / variable:   GMC08   TEWL_adj

ID, description, units MPD:55701   TEWL_adj   transepidermal water loss, normalized   [g/m2/h]  
Data set, strains GMC08   inbred w/CC8   8 strains     sex: both     age: 11-12wks
Procedure condenser chamber
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  STRAIN COMPARISON PLOT
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GMC08 - transepidermal water loss, normalized



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means-2.00   g/m2/h 2.61   g/m2/h
Median of the strain means-1.67   g/m2/h 2.23   g/m2/h
SD of the strain means± 4.90 ± 5.58
Coefficient of variation (CV)-2.45 2.14
Min–max range of strain means-10.8   –   3.97   g/m2/h -5.41   –   12.0   g/m2/h
Mean sample size per strain17.4   mice 16.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1517.132 1517.132 36.5105 < 0.0001
strain 7 5335.2336 762.1762 18.3422 < 0.0001
sex:strain 7 918.0114 131.1445 3.1561 0.0032
Residuals 253 10512.9757 41.5533


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.62 4.71   16 1.18 2.9 -5.32, 9.78 0.74
129S1/SvImJ m 3.87 5.85   16 1.46 1.51 -3.23, 15.3 0.23
A/J f 3.97 6.68   16 1.67 1.68 -10.2, 14.8 1.22
A/J m 4.23 5.67   16 1.42 1.34 -10.8, 12.8 0.29
C57BL/6J f -1.93 4.02   16 1.0 -2.09 -10.0, 3.61 0.01
C57BL/6J m 12.0 12.6   14 3.37 1.05 -5.13, 38.9 1.68
CAST/EiJ f -10.8 4.81   19 1.1 -0.447 -15.8, 1.58 -1.79
CAST/EiJ m -5.41 10.4   15 2.69 -1.92 -16.6, 20.9 -1.44
NOD/ShiLtJ f -1.4 4.23   18 0.998 -3.02 -10.3, 7.57 0.12
NOD/ShiLtJ m 0.585 4.79   16 1.2 8.19 -6.63, 7.58 -0.36
NZO/HlLtJ f 2.64 4.83   16 1.21 1.83 -5.32, 11.7 0.95
NZO/HlLtJ m 7.92 7.13   17 1.73 0.901 -4.52, 21.8 0.95
PWK/PhJ f -4.16 4.6   20 1.03 -1.11 -13.5, 3.81 -0.44
PWK/PhJ m -0.789 7.65   20 1.71 -9.69 -11.1, 26.0 -0.61
WSB/EiJ f -5.95 4.49   18 1.06 -0.756 -11.9, 1.68 -0.81
WSB/EiJ m -1.53 6.34   16 1.58 -4.14 -9.33, 10.3 -0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.6225 1.6115 4.7963 -1.5513
129S1/SvImJ m 3.8725 1.6115 7.0463 0.6987
A/J f 3.9663 1.6115 7.14 0.7925
A/J m 4.235 1.6115 7.4088 1.0612
C57BL/6J f -1.9275 1.6115 1.2463 -5.1013
C57BL/6J m 11.9529 1.7228 15.3457 8.56
CAST/EiJ f -10.7589 1.4789 -7.8465 -13.6714
CAST/EiJ m -5.4147 1.6644 -2.1368 -8.6925
NOD/ShiLtJ f -1.4 1.5194 1.5922 -4.3922
NOD/ShiLtJ m 0.585 1.6115 3.7588 -2.5888
NZO/HlLtJ f 2.6438 1.6115 5.8175 -0.53
NZO/HlLtJ m 7.9165 1.5634 10.9955 4.8375
PWK/PhJ f -4.1585 1.4414 -1.3198 -6.9972
PWK/PhJ m -0.7895 1.4414 2.0492 -3.6282
WSB/EiJ f -5.9489 1.5194 -2.9566 -8.9411
WSB/EiJ m -1.5325 1.6115 1.6413 -4.7063


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.7475 1.1395 4.9917 0.5033
A/J both 4.1006 1.1395 6.3448 1.8564
C57BL/6J both 5.0127 1.1795 7.3356 2.6897
CAST/EiJ both -8.0868 1.1132 -5.8944 -10.2792
NOD/ShiLtJ both -0.4075 1.1074 1.7735 -2.5885
NZO/HlLtJ both 5.2801 1.1227 7.491 3.0692
PWK/PhJ both -2.474 1.0192 -0.4667 -4.4813
WSB/EiJ both -3.7407 1.1074 -1.5597 -5.9216




  GWAS USING LINEAR MIXED MODELS