Project measure / variable:   GMC08   TEWL_CV

ID, description, units MPD:55702   TEWL_CV   coefficient of variation of transepidermal water loss single measurements   [%]  
Data set, strains GMC08   inbred w/CC8   8 strains     sex: both     age: 11-12wks
Procedure condenser chamber
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  STRAIN COMPARISON PLOT
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GMC08 - coefficient of variation of transepidermal water loss single measurements



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means0.351   % 0.295   %
Median of the strain means0.372   % 0.265   %
SD of the strain means± 0.0953 ± 0.0785
Coefficient of variation (CV)0.272 0.266
Min–max range of strain means0.221   –   0.499   % 0.236   –   0.467   %
Mean sample size per strain17.4   mice 16.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.2441 0.2441 5.4047 0.0209
strain 7 1.6299 0.2328 5.1553 < 0.0001
sex:strain 7 0.1367 0.0195 0.4323 0.8815
Residuals 253 11.4269 0.0452


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.221 0.142   16 0.0355 0.644 0.02, 0.48 -1.36
129S1/SvImJ m 0.244 0.164   16 0.041 0.673 0.02, 0.47 -0.65
A/J f 0.244 0.185   16 0.0462 0.758 0.02, 0.57 -1.12
A/J m 0.236 0.146   16 0.0364 0.617 0.04, 0.45 -0.75
C57BL/6J f 0.367 0.239   16 0.0599 0.652 0.04, 0.84 0.17
C57BL/6J m 0.245 0.162   14 0.0433 0.662 0.03, 0.5 -0.63
CAST/EiJ f 0.499 0.255   19 0.0586 0.512 0.05, 1.14 1.56
CAST/EiJ m 0.467 0.378   15 0.0976 0.81 0.08, 1.3 2.19
NOD/ShiLtJ f 0.281 0.146   18 0.0345 0.522 0.08, 0.55 -0.73
NOD/ShiLtJ m 0.238 0.155   16 0.0389 0.655 0.02, 0.5 -0.72
NZO/HlLtJ f 0.378 0.243   16 0.0608 0.643 0.04, 0.78 0.29
NZO/HlLtJ m 0.286 0.203   17 0.0492 0.708 0.05, 0.63 -0.11
PWK/PhJ f 0.384 0.161   20 0.0359 0.418 0.05, 0.69 0.35
PWK/PhJ m 0.309 0.158   20 0.0353 0.511 0.04, 0.62 0.18
WSB/EiJ f 0.431 0.32   18 0.0754 0.743 0.05, 1.25 0.84
WSB/EiJ m 0.333 0.189   16 0.0472 0.567 0.08, 0.66 0.49


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.2206 0.0531 0.3253 0.116
129S1/SvImJ m 0.2438 0.0531 0.3484 0.1391
A/J f 0.2437 0.0531 0.3484 0.1391
A/J m 0.2362 0.0531 0.3409 0.1316
C57BL/6J f 0.3675 0.0531 0.4721 0.2629
C57BL/6J m 0.245 0.0568 0.3569 0.1331
CAST/EiJ f 0.4989 0.0488 0.595 0.4029
CAST/EiJ m 0.4667 0.0549 0.5747 0.3586
NOD/ShiLtJ f 0.2806 0.0501 0.3792 0.1819
NOD/ShiLtJ m 0.2375 0.0531 0.3421 0.1329
NZO/HlLtJ f 0.3781 0.0531 0.4828 0.2735
NZO/HlLtJ m 0.2865 0.0515 0.388 0.185
PWK/PhJ f 0.384 0.0475 0.4776 0.2904
PWK/PhJ m 0.309 0.0475 0.4026 0.2154
WSB/EiJ f 0.4306 0.0501 0.5292 0.3319
WSB/EiJ m 0.3331 0.0531 0.4378 0.2285


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.2322 0.0376 0.3062 0.1582
A/J both 0.24 0.0376 0.314 0.166
C57BL/6J both 0.3062 0.0389 0.3828 0.2297
CAST/EiJ both 0.4828 0.0367 0.5551 0.4105
NOD/ShiLtJ both 0.259 0.0365 0.3309 0.1871
NZO/HlLtJ both 0.3323 0.037 0.4052 0.2594
PWK/PhJ both 0.3465 0.0336 0.4127 0.2803
WSB/EiJ both 0.3818 0.0365 0.4537 0.3099




  GWAS USING LINEAR MIXED MODELS