Phenotype measure:   Crabbe3   ARR2_improvement

ID, description, units MPD:15851   ARR2_improvement   accelerating rotarod (ARR2) acquisition trial average of first 2 trials minus average of last 2 trials (20 rpm/min)   [s]
Data set, strains Crabbe3   inbred   13 strains     sex: both     age: 9-17wks
Procedure rotarod
Ontology mappings

  STRAIN COMPARISON PLOT
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Crabbe3 - accelerating rotarod (ARR2) acquisition trial average of first 2 trials minus average of last 2 trials (20 rpm/min)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains21 strains
Mean of the strain means26.3   s 24.7   s
Median of the strain means20.0   s 20.2   s
SD of the strain means± 14.8 ± 15.9
Coefficient of variation (CV)0.562 0.646
Min–max range of strain means8.00   –   57.1   s 6.40   –   56.8   s
Mean sample size per strain9.5   mice 9.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 271.8581 271.8581 0.7292 0.3937
strain 20 75256.3234 3762.8162 10.0927 < 0.0001
sex:strain 20 15129.7932 756.4897 2.0291 0.006
Residuals 347 129370.2374 372.8249


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 19.6 14.0   10 4.43 0.717 -3.5, 40.0 -0.45
129S1/SvImJ m 20.2 12.7   10 4.03 0.63 6.5, 52.5 -0.28
A/J f 13.3 9.68   8 3.42 0.727 0.5, 25.5 -0.88
A/J m 6.4 7.4   10 2.34 1.16 -4.0, 17.0 -1.15
AKR/J f 19.4 15.3   10 4.84 0.79 -2.5, 49.5 -0.47
AKR/J m 45.2 21.2   8 7.51 0.469 -1.5, 71.0 1.29
BALB/cByJ f 22.4 11.2   10 3.53 0.499 -1.0, 36.0 -0.26
BALB/cByJ m 15.2 4.52   10 1.43 0.296 8.5, 23.0 -0.59
BTBR T+ Itpr3tf/J f 50.6 37.2   11 11.2 0.736 7.5, 118.0 1.65
BTBR T+ Itpr3tf/J m 13.9 12.0   6 4.88 0.86 -1.0, 35.0 -0.68
C3H/HeJ f 12.8 14.0   10 4.42 1.09 -18.0, 29.5 -0.91
C3H/HeJ m 7.75 11.6   8 4.12 1.5 -8.0, 24.5 -1.06
C57BL/6J f 18.5 13.6   8 4.81 0.735 -9.5, 33.0 -0.53
C57BL/6J m 26.4 13.3   10 4.21 0.504 4.0, 42.5 0.11
C57L/J f 24.4 26.8   10 8.47 1.1 -22.0, 67.5 -0.13
C57L/J m 31.8 17.1   8 6.04 0.538 10.5, 51.5 0.45
C58/J f 23.1 18.9   10 5.99 0.82 2.5, 52.0 -0.21
C58/J m 16.6 20.4   10 6.46 1.23 -5.0, 59.5 -0.51
CAST/EiJ f 32.9 12.3   8 4.34 0.374 11.0, 46.0 0.45
CAST/EiJ m 24.1 18.9   8 6.69 0.784 -1.0, 59.5 -0.03
DBA/2J f 16.6 14.2   10 4.5 0.858 -5.0, 43.5 -0.65
DBA/2J m 6.62 8.73   8 3.09 1.32 -4.0, 22.5 -1.13
FVB/NJ f 14.8 5.45   10 1.72 0.37 7.0, 23.0 -0.78
FVB/NJ m 7.68 10.7   11 3.22 1.39 -4.0, 29.5 -1.07
MOLF/EiJ f 29.2 22.5   8 7.95 0.77 5.5, 73.5 0.2


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 19.55 6.1059 31.5593 7.5407
129S1/SvImJ m 20.2 6.1059 32.2093 8.1907
A/J f 13.3125 6.8266 26.7393 0.0
A/J m 6.4 6.1059 18.4093 0.0
AKR/J f 19.35 6.1059 31.3593 7.3407
AKR/J m 45.25 6.8266 58.6768 31.8232
BALB/cByJ f 22.35 6.1059 34.3593 10.3407
BALB/cByJ m 15.25 6.1059 27.2593 3.2407
BTBR T+ Itpr3tf/J f 50.5909 5.8218 62.0413 39.1405
BTBR T+ Itpr3tf/J m 13.9167 7.8827 29.4206 0.0
C3H/HeJ f 12.85 6.1059 24.8593 0.8407
C3H/HeJ m 7.75 6.8266 21.1768 0.0
C57BL/6J f 18.5 6.8266 31.9268 5.0732
C57BL/6J m 26.4 6.1059 38.4093 14.3907
C57L/J f 24.45 6.1059 36.4593 12.4407
C57L/J m 31.75 6.8266 45.1768 18.3232
C58/J f 23.1 6.1059 35.1093 11.0907
C58/J m 16.55 6.1059 28.5593 4.5407
CAST/EiJ f 32.875 6.8266 46.3018 19.4482
CAST/EiJ m 24.125 6.8266 37.5518 10.6982
DBA/2J f 16.6 6.1059 28.6093 4.5907
DBA/2J m 6.625 6.8266 20.0518 0.0
FVB/NJ f 14.75 6.1059 26.7593 2.7407
FVB/NJ m 7.6818 5.8218 19.1322 0.0
MOLF/EiJ f 29.1875 6.8266 42.6143 15.7607
MOLF/EiJ m 29.2857 7.298 43.6396 14.9318
NOD/ShiLtJ f 51.9167 5.5739 62.8796 40.9537
NOD/ShiLtJ m 55.625 5.5739 66.5879 44.6621
NZB/BlNJ f 8.0 7.8827 23.5039 0.0
NZB/BlNJ m 18.8333 5.5739 29.7963 7.8704
PERA/EiJ f 37.3333 6.4362 49.9923 24.6744
PERA/EiJ m 43.875 5.5739 54.8379 32.9121
PL/J f 57.125 5.5739 68.0879 46.1621
PL/J m 56.8125 6.8266 70.2393 43.3857
SJL/J f 10.25 6.8266 23.6768 0.0
SJL/J m 9.2917 5.5739 20.2546 0.0
SM/J f 20.0357 5.1605 30.1854 9.886
SM/J m 17.7 6.1059 29.7093 5.6907
SPRET/EiJ f 49.6667 11.1479 71.5926 27.7408
SPRET/EiJ m 21.0 13.6533 47.8536 0.0
SWR/J f 19.7 6.1059 31.7093 7.6907
SWR/J m 43.45 6.1059 55.4593 31.4407


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 19.875 4.3176 28.3669 11.3831
A/J both 9.8562 4.5795 18.8632 0.8493
AKR/J both 32.3 4.5795 41.307 23.293
BALB/cByJ both 18.8 4.3176 27.2919 10.3081
BTBR T+ Itpr3tf/J both 32.2538 4.8998 41.8908 22.6168
C3H/HeJ both 10.3 4.5795 19.307 1.293
C57BL/6J both 22.45 4.5795 31.457 13.443
C57L/J both 28.1 4.5795 37.107 19.093
C58/J both 19.825 4.3176 28.3169 11.3331
CAST/EiJ both 28.5 4.8272 37.9942 19.0058
DBA/2J both 11.6125 4.5795 20.6195 2.6055
FVB/NJ both 11.2159 4.2183 19.5125 2.9193
MOLF/EiJ both 29.2366 4.9966 39.064 19.4092
NOD/ShiLtJ both 53.7708 3.9414 61.5228 46.0189
NZB/BlNJ both 13.4167 4.8272 22.9109 3.9225
PERA/EiJ both 40.6042 4.2572 48.9773 32.2311
PL/J both 56.9687 4.4066 65.6357 48.3018
SJL/J both 9.7708 4.4066 18.4378 1.1039
SM/J both 18.8679 3.9973 26.7298 11.0059
SPRET/EiJ both 35.3333 8.8132 52.6673 17.9994
SWR/J both 31.575 4.3176 40.0669 23.0831




  GWAS USING LINEAR MIXED MODELS