Phenotype measure:   Crabbe3   ARR2_performance

ID, description, units MPD:15850   ARR2_performance   accelerating rotarod (ARR2) acquisition trial average over all trials (20 rpm/min)   [s]
Data set, strains Crabbe3   inbred   21 strains     sex: both     age: 9-17wks
Procedure rotarod
Ontology mappings

  STRAIN COMPARISON PLOT
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Crabbe3 - accelerating rotarod (ARR2) acquisition trial average over all trials (20 rpm/min)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains21 strains
Mean of the strain means44.4   s 40.3   s
Median of the strain means43.1   s 39.0   s
SD of the strain means± 13.0 ± 13.9
Coefficient of variation (CV)0.293 0.345
Min–max range of strain means28.6   –   73.8   s 19.6   –   68.3   s
Mean sample size per strain9.7   mice 9.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2912.3774 2912.3774 11.5216 0.0008
strain 20 66651.0812 3332.5541 13.1838 < 0.0001
sex:strain 20 5222.6256 261.1313 1.0331 0.4218
Residuals 354 89482.7852 252.7762


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 30.4 14.7   10 4.66 0.485 10.7, 46.5 -1.08
129S1/SvImJ m 31.3 15.1   10 4.78 0.483 13.3, 59.7 -0.65
A/J f 31.8 9.67   8 3.42 0.304 13.5, 43.9 -0.97
A/J m 23.2 10.4   10 3.28 0.448 9.4, 42.3 -1.23
AKR/J f 44.2 18.0   10 5.69 0.407 13.5, 73.7 -0.02
AKR/J m 54.2 14.0   8 4.95 0.258 30.7, 77.8 1.0
BALB/cByJ f 42.5 12.0   10 3.78 0.282 27.8, 58.8 -0.15
BALB/cByJ m 31.7 15.9   10 5.04 0.502 12.7, 53.8 -0.62
BTBR T+ Itpr3tf/J f 39.0 19.0   12 5.49 0.488 15.6, 74.6 -0.42
BTBR T+ Itpr3tf/J m 28.1 17.2   6 7.04 0.613 15.0, 62.2 -0.88
C3H/HeJ f 33.2 12.7   10 4.01 0.383 20.1, 57.3 -0.86
C3H/HeJ m 30.3 7.35   8 2.6 0.242 18.8, 45.0 -0.72
C57BL/6J f 44.1 10.1   8 3.58 0.229 33.8, 58.1 -0.02
C57BL/6J m 45.1 9.11   10 2.88 0.202 31.7, 62.0 0.35
C57L/J f 46.5 12.6   10 3.98 0.271 31.3, 71.8 0.16
C57L/J m 39.0 16.2   8 5.73 0.415 24.8, 71.4 -0.09
C58/J f 51.8 31.0   10 9.79 0.597 16.1, 98.8 0.57
C58/J m 38.3 18.7   10 5.92 0.489 12.3, 65.1 -0.14
CAST/EiJ f 44.7 20.7   10 6.54 0.463 14.5, 76.1 0.02
CAST/EiJ m 47.7 17.5   9 5.83 0.367 23.2, 70.6 0.53
DBA/2J f 30.7 10.9   10 3.44 0.355 13.0, 43.9 -1.05
DBA/2J m 19.6 4.6   8 1.63 0.234 13.1, 27.6 -1.49
FVB/NJ f 32.0 11.5   10 3.64 0.36 21.4, 54.1 -0.95
FVB/NJ m 23.4 8.72   11 2.63 0.372 13.0, 40.8 -1.21
MOLF/EiJ f 51.5 20.2   8 7.14 0.392 30.2, 85.1 0.54
MOLF/EiJ m 42.3 17.7   7 6.71 0.419 19.1, 62.9 0.14
NOD/ShiLtJ f 65.5 25.6   12 7.38 0.39 30.8, 117.0 1.62
NOD/ShiLtJ m 65.2 18.3   12 5.3 0.281 26.1, 87.9 1.79
NZB/BlNJ f 34.0 4.15   6 1.69 0.122 27.4, 37.9 -0.8
NZB/BlNJ m 27.4 7.85   12 2.27 0.286 12.7, 39.1 -0.93
PERA/EiJ f 70.8 24.0   10 7.58 0.339 36.0, 106.0 2.03
PERA/EiJ m 56.7 13.1   12 3.79 0.231 29.3, 77.9 1.18
PL/J f 73.8 18.6   12 5.38 0.252 40.9, 102.0 2.26
PL/J m 68.3 7.96   8 2.81 0.116 58.0, 79.1 2.01
SJL/J f 28.6 7.46   8 2.64 0.261 17.4, 41.1 -1.21
SJL/J m 31.2 10.9   12 3.14 0.348 11.6, 46.3 -0.65
SM/J f 52.2 13.9   14 3.72 0.267 26.3, 76.2 0.6
SM/J m 39.6 12.6   10 4.0 0.319 22.2, 60.7 -0.05
SPRET/EiJ f 43.1 23.2   5 10.4 0.54 15.0, 71.4 -0.1
SPRET/EiJ m 51.4 27.4   2   19.4 0.534 32.0, 70.8 0.8
SWR/J f 42.3 18.4   10 5.8 0.434 19.7, 71.7 -0.16
SWR/J m 52.0 19.4   10 6.14 0.374 23.6, 83.3 0.84


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 30.42 5.0277 40.3079 20.5321
129S1/SvImJ m 31.3 5.0277 41.1879 21.4121
A/J f 31.8 5.6211 42.855 20.745
A/J m 23.17 5.0277 33.0579 13.2821
AKR/J f 44.22 5.0277 54.1079 34.3321
AKR/J m 54.2 5.6211 65.255 43.145
BALB/cByJ f 42.45 5.0277 52.3379 32.5621
BALB/cByJ m 31.72 5.0277 41.6079 21.8321
BTBR T+ Itpr3tf/J f 38.975 4.5896 48.0014 29.9486
BTBR T+ Itpr3tf/J m 28.1167 6.4907 40.8819 15.3515
C3H/HeJ f 33.18 5.0277 43.0679 23.2921
C3H/HeJ m 30.3375 5.6211 41.3925 19.2825
C57BL/6J f 44.0875 5.6211 55.1425 33.0325
C57BL/6J m 45.11 5.0277 54.9979 35.2221
C57L/J f 46.46 5.0277 56.3479 36.5721
C57L/J m 39.0125 5.6211 50.0675 27.9575
C58/J f 51.84 5.0277 61.7279 41.9521
C58/J m 38.32 5.0277 48.2079 28.4321
CAST/EiJ f 44.66 5.0277 54.5479 34.7721
CAST/EiJ m 47.7333 5.2996 58.1561 37.3106
DBA/2J f 30.68 5.0277 40.5679 20.7921
DBA/2J m 19.625 5.6211 30.68 8.57
FVB/NJ f 32.0 5.0277 41.8879 22.1121
FVB/NJ m 23.4364 4.7937 32.8641 14.0086
MOLF/EiJ f 51.5125 5.6211 62.5675 40.4575
MOLF/EiJ m 42.3429 6.0092 54.1611 30.5246
NOD/ShiLtJ f 65.4667 4.5896 74.493 56.4403
NOD/ShiLtJ m 65.1917 4.5896 74.218 56.1653
NZB/BlNJ f 34.0333 6.4907 46.7985 21.2681
NZB/BlNJ m 27.4083 4.5896 36.4347 18.382
PERA/EiJ f 70.77 5.0277 80.6579 60.8821
PERA/EiJ m 56.6917 4.5896 65.718 47.6653
PL/J f 73.8167 4.5896 82.843 64.7903
PL/J m 68.3375 5.6211 79.3925 57.2825
SJL/J f 28.625 5.6211 39.68 17.57
SJL/J m 31.2333 4.5896 40.2597 22.207
SM/J f 52.2143 4.2492 60.5711 43.8575
SM/J m 39.64 5.0277 49.5279 29.7521
SPRET/EiJ f 43.06 7.1102 57.0436 29.0764
SPRET/EiJ m 51.4 11.2422 73.51 29.29
SWR/J f 42.31 5.0277 52.1979 32.4221
SWR/J m 51.97 5.0277 61.8579 42.0821


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 30.86 3.5551 37.8518 23.8682
A/J both 27.485 3.7708 34.9009 20.0691
AKR/J both 49.21 3.7708 56.6259 41.7941
BALB/cByJ both 37.085 3.5551 44.0768 30.0932
BTBR T+ Itpr3tf/J both 33.5458 3.9747 41.3629 25.7288
C3H/HeJ both 31.7588 3.7708 39.1747 24.3428
C57BL/6J both 44.5987 3.7708 52.0147 37.1828
C57L/J both 42.7363 3.7708 50.1522 35.3203
C58/J both 45.08 3.5551 52.0718 38.0882
CAST/EiJ both 46.1967 3.6525 53.3801 39.0133
DBA/2J both 25.1525 3.7708 32.5684 17.7366
FVB/NJ both 27.7182 3.4734 34.5492 20.8871
MOLF/EiJ both 46.9277 4.1142 55.0191 38.8363
NOD/ShiLtJ both 65.3292 3.2454 71.7118 58.9466
NZB/BlNJ both 30.7208 3.9747 38.5379 22.9038
PERA/EiJ both 63.7308 3.4038 70.425 57.0367
PL/J both 71.0771 3.6284 78.2131 63.9411
SJL/J both 29.9292 3.6284 37.0651 22.7932
SM/J both 45.9271 3.2914 52.4003 39.454
SPRET/EiJ both 47.23 6.651 60.3104 34.1496
SWR/J both 47.14 3.5551 54.1318 40.1482




  GWAS USING LINEAR MIXED MODELS