Project measures / variables set:   Wiltshire4   Bcells_BEZ

ID, description, units MPD:52401   Bcells_BEZ   B cells, percent viability   [%]  
BEZ235 study
Measures
• dose [µM]:    • control    • 0.046    • 0.137    • 1.235    • 11.1    • 100
Data set, strains Wiltshire4   inbred w/CC7   34 strains     sex: m     age: 10wks
Procedure immune cell quantification
Comparisoncontrol group vs. multiple treatment / dosage groups
Ontology mappings

  SIDE-BY-SIDE STRAIN CURVES
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  OVERLAPPING STRAIN CURVES
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Wiltshire4 - B cells, percent viability




  ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary     

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
dose 5 36387.2562 7277.4512 9.879 < 0.0001
strain 33 176820.9163 5358.2096 7.2736 < 0.0001
dose:strain 165 227756.6316 1380.3432 1.8738 < 0.0001
Residuals 594 437577.1234 736.6618

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDTreatmentMeasure / Variable Description PanelStrains
tested
SexAge
Wiltshire4 52401 immune cell quantification BEZ235 B cells, percent viability   [%]   control  Bcells_BEZ_ctrl inbred w/CC7 34 m 10wks
Wiltshire4 52402 immune cell quantification BEZ235 B cells, percent viability   [%]   dose: 0.046 µM  Bcells_BEZ_A inbred w/CC7 34 m 10wks
Wiltshire4 52403 immune cell quantification BEZ235 B cells, percent viability   [%]   dose: 0.137 µM  Bcells_BEZ_B inbred w/CC7 34 m 10wks
Wiltshire4 52404 immune cell quantification BEZ235 B cells, percent viability   [%]   dose: 1.235 µM  Bcells_BEZ_C inbred w/CC7 34 m 10wks
Wiltshire4 52405 immune cell quantification BEZ235 B cells, percent viability   [%]   dose: 11.1 µM  Bcells_BEZ_D inbred w/CC7 34 m 10wks
Wiltshire4 52406 immune cell quantification BEZ235 B cells, percent viability   [%]   dose: 100 µM  Bcells_BEZ_E inbred w/CC7 34 m 10wks