MPD: Project measures / variables set: Yuan3 ALT

Project measures / variables set: Yuan3 ALT

ID, description, units	MPD:24401 ALT alanine transaminase (plasma ALT) [IU/L]
Measures	• 6mo • 12mo • 18mo
Data set, strains	Yuan3 inbred 32 strains sex: both
Procedure	metabolic panel
Comparison	timecourse, same cohort (aging study)
Ontology mappings	VT:0001573 blood alanine transaminase amount MA:0002501 plasma MP:0001573 abnormal circulating alanine transaminase level

Values Means Δ Means Z-scores

Graph Type Points Bars

Dimensions Width: × Height: px

Plot Options Hide Error Bars Strains on X-axis

ANOVA Summary "within" = Within error "between" = Between Error (Animal ID)

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
between sex	1	314.3809	314.3809	1.203	0.2812
between strain	3	29858.1626	9952.7209	38.0842	< 0.0001
between sex:strain	3	3823.7368	1274.5789	4.8772	0.0068
between Residuals	31	8101.3778	261.3348
within age	2	576.1197	288.0598	1.751	0.1821
within age:sex	2	181.6023	90.8011	0.5519	0.5786
within age:strain	6	7458.015	1243.0025	7.5557	< 0.0001
within age:sex:strain	6	2169.1408	361.5235	2.1975	0.055
within Residuals	62	10199.7889	164.5127

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Yuan3	24401	metabolic panel	(none)	alanine transaminase (plasma ALT) [IU/L] at age 6mo ALT_M06	inbred	31	both	26wks
Yuan3	24402	metabolic panel	(none)	alanine transaminase (plasma ALT) [IU/L] at age 12mo ALT_M12	inbred	31	both	52wks
Yuan3	24403	metabolic panel	(none)	alanine transaminase (plasma ALT) [IU/L] at age 18mo ALT_M18	inbred	29	both	78wks