Phenotype measure:   Naggert1   GLU_foldchg_fat17

ID, description, units MPD:14304   GLU_foldchg_fat17   glucose (plasma GLU, 4h fast)   [mg/dL]  fold change
high-fat diet study
Data set, strains Naggert1   inbred w/CC7   42 strains     sex: both     age: 7-9wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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Naggert1 - glucose (plasma GLU, 4h fast) fold change



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested42 strains39 strains
Mean of the strain means0.911   mg/dL 0.901   mg/dL
Median of the strain means0.885   mg/dL 0.888   mg/dL
SD of the strain means± 0.205 ± 0.219
Coefficient of variation (CV)0.225 0.243
Min–max range of strain means0.546   –   1.68   mg/dL 0.458   –   1.50   mg/dL
Mean sample size per strain8.8   mice 8.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0312 0.0312 0.2722 0.602
strain 38 20.0443 0.5275 4.6062 < 0.0001
sex:strain 38 8.2419 0.2169 1.894 0.0012
Residuals 589 67.4492 0.1145


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.676 0.104   10 0.0329 0.154 0.533, 0.866 -1.15
129S1/SvImJ m 0.678 0.167   9 0.0557 0.247 0.445, 0.962 -1.02
A/J f 0.546 0.0667   10 0.0211 0.122 0.434, 0.643 -1.78
A/J m 0.458 0.154   9 0.0513 0.336 0.075, 0.588 -2.03
AKR/J f 0.715 0.215   12 0.062 0.3 0.238, 1.01 -0.96
BALB/cByJ f 0.75 0.153   11 0.046 0.203 0.55, 1.03 -0.79
BALB/cByJ m 0.869 0.26   8 0.092 0.3 0.518, 1.24 -0.15
BALB/cJ f 0.725 0.126   9 0.0421 0.174 0.595, 1.01 -0.91
BALB/cJ m 0.795 0.0963   10 0.0304 0.121 0.578, 0.878 -0.49
BTBR T+ Itpr3tf/J f 1.04 0.169   8 0.0597 0.162 0.799, 1.31 0.63
BTBR T+ Itpr3tf/J m 1.07 0.201   7 0.0758 0.187 0.84, 1.42 0.77
BUB/BnJ f 1.06 0.304   10 0.0962 0.287 0.583, 1.47 0.73
BUB/BnJ m 0.992 0.177   5 0.0791 0.178 0.766, 1.23 0.42
C3H/HeJ f 0.938 0.169   10 0.0535 0.18 0.639, 1.14 0.13
C3H/HeJ m 0.825 0.215   8 0.0762 0.261 0.475, 1.15 -0.35
C57BL/10J f 0.856 0.177   9 0.0591 0.207 0.63, 1.09 -0.27
C57BL/10J m 0.728 0.151   10 0.0479 0.208 0.361, 0.867 -0.79
C57BL/6J f 0.857 0.153   10 0.0485 0.179 0.659, 1.1 -0.26
C57BL/6J m 0.861 0.192   10 0.0606 0.222 0.648, 1.22 -0.18
C57BLKS/J f 0.838 0.165   9 0.0551 0.197 0.616, 1.14 -0.36
C57BLKS/J m 0.707 0.109   5 0.0485 0.153 0.594, 0.868 -0.89
C57BR/cdJ f 1.22 0.368   10 0.116 0.301 0.746, 2.06 1.51
C57BR/cdJ m 1.27 0.383   10 0.121 0.301 0.846, 2.15 1.69
C57L/J f 0.94 0.195   10 0.0618 0.208 0.613, 1.35 0.14
C57L/J m 0.968 0.161   10 0.051 0.167 0.797, 1.31 0.31
C58/J f 0.604 0.0669   5 0.0299 0.111 0.529, 0.674 -1.5
C58/J m 0.955 0.31   7 0.117 0.325 0.731, 1.44 0.25
CAST/EiJ f 0.756 0.126   9 0.042 0.167 0.595, 1.01 -0.76
CAST/EiJ m 0.795 0.326   8 0.115 0.41 0.442, 1.47 -0.49
CBA/J f 0.942 0.187   8 0.0662 0.199 0.751, 1.3 0.15
CBA/J m 0.775 0.176   8 0.0623 0.228 0.543, 1.0 -0.58
CZECHII/EiJ f 0.785 0.489   11 0.147 0.623 0.203, 1.86 -0.62
CZECHII/EiJ m 0.906 0.78   9 0.26 0.86 0.304, 2.63 0.02
DBA/1J f 0.921 0.156   7 0.0589 0.169 0.729, 1.12 0.05
DBA/1J m 0.883 0.474   8 0.167 0.536 0.29, 1.93 -0.08
DBA/2J f 0.956 0.0972   9 0.0324 0.102 0.835, 1.11 0.22
DBA/2J m 0.906 0.167   9 0.0557 0.184 0.711, 1.24 0.02
FVB/NJ f 0.967 0.154   8 0.0545 0.159 0.791, 1.29 0.27
FVB/NJ m 0.647 0.12   5 0.0536 0.185 0.553, 0.847 -1.16
I/LnJ f 0.823 0.136   10 0.043 0.165 0.667, 1.06 -0.43
I/LnJ m 1.09 0.175   9 0.0584 0.161 0.829, 1.39 0.86
JF1/MsJ f 0.783 0.159   10 0.0504 0.203 0.592, 1.11 -0.62
JF1/MsJ m 0.649 0.192   7 0.0726 0.296 0.404, 0.915 -1.15
KK/HlJ f 0.784 0.106   7 0.0402 0.136 0.671, 0.973 -0.62
LP/J f 1.31 0.331   10 0.105 0.253 0.892, 1.88 1.95
LP/J m 1.13 0.198   12 0.0572 0.176 0.786, 1.38 1.05
MA/MyJ f 0.884 0.284   10 0.0897 0.321 0.47, 1.51 -0.13
MA/MyJ m 0.746 0.174   10 0.0551 0.234 0.516, 1.05 -0.71
MOLF/EiJ f 0.557 0.0961   7 0.0363 0.173 0.427, 0.665 -1.73
MOLF/EiJ m 0.52 0.135   9 0.0449 0.259 0.307, 0.767 -1.74
MSM/MsJ f 0.951 0.128   5 0.0575 0.135 0.851, 1.18 0.2
MSM/MsJ m 1.12 0.238   11 0.0718 0.214 0.717, 1.59 1.0
NOD/ShiLtJ f 1.23 0.492   7 0.186 0.399 0.785, 2.23 1.56
NOD/ShiLtJ m 1.5 1.06   4 0.529 0.706 0.819, 3.08 2.74
NON/ShiLtJ f 0.879 0.571   10 0.181 0.649 0.358, 2.34 -0.16
NON/ShiLtJ m 1.32 0.96   12 0.277 0.727 0.621, 3.49 1.92
NZB/BlNJ f 0.992 0.475   12 0.137 0.479 0.606, 2.38 0.4
NZB/BlNJ m 0.99 0.236   9 0.0788 0.239 0.648, 1.24 0.41
NZW/LacJ f 0.951 0.0806   9 0.0269 0.0848 0.832, 1.09 0.2
NZW/LacJ m 0.922 0.25   8 0.0884 0.271 0.66, 1.34 0.09
PERA/EiJ f 1.04 0.269   9 0.0897 0.259 0.504, 1.39 0.63
PERA/EiJ m 0.994 0.179   8 0.0632 0.18 0.702, 1.23 0.42
PL/J f 0.918 0.313   10 0.0988 0.34 0.504, 1.43 0.03
PL/J m 0.712 0.0473   5 0.0211 0.0664 0.629, 0.749 -0.87
PWK/PhJ f 1.05 0.192   9 0.0639 0.183 0.799, 1.41 0.68
PWK/PhJ m 0.948 0.236   8 0.0836 0.249 0.594, 1.43 0.21
RF/J f 0.995 0.248   7 0.0937 0.249 0.69, 1.29 0.41
RIIIS/J f 0.851 0.133   6 0.0543 0.156 0.704, 1.1 -0.29
RIIIS/J m 0.888 0.182   8 0.0643 0.205 0.602, 1.1 -0.06
SEA/GnJ f 0.826 0.169   9 0.0563 0.204 0.633, 1.13 -0.41
SEA/GnJ m 1.07 0.168   7 0.0634 0.157 0.886, 1.39 0.77
SJL/J f 0.838 0.209   9 0.0697 0.249 0.55, 1.19 -0.36
SJL/J m 0.7 0.251   12 0.0725 0.359 0.157, 1.22 -0.92
SM/J f 0.887 0.229   8 0.0809 0.258 0.626, 1.35 -0.12
SM/J m 1.11 0.232   9 0.0773 0.21 0.733, 1.4 0.95
SPRET/EiJ f 1.12 0.116   4 0.0578 0.103 1.03, 1.28 1.02
SPRET/EiJ m 1.18 0.474   5 0.212 0.4 0.736, 1.97 1.28
SWR/J f 0.816 0.208   8 0.0734 0.255 0.65, 1.15 -0.46
SWR/J m 0.795 0.11   7 0.0417 0.139 0.6, 0.925 -0.49
WSB/EiJ f 1.68 1.52   8 0.537 0.903 0.422, 4.82 3.76
WSB/EiJ m 0.677 0.213   9 0.0708 0.314 0.453, 1.07 -1.03


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.6763 0.107 0.8865 0.4661
129S1/SvImJ m 0.6778 0.1128 0.8993 0.4562
A/J f 0.5461 0.107 0.7563 0.3359
A/J m 0.4581 0.1128 0.6797 0.2366
BALB/cByJ f 0.7499 0.102 0.9503 0.5495
BALB/cByJ m 0.8689 0.1196 1.1039 0.6339
BALB/cJ f 0.7249 0.1128 0.9464 0.5033
BALB/cJ m 0.7946 0.107 1.0048 0.5844
BTBR T+ Itpr3tf/J f 1.0401 0.1196 1.2751 0.8051
BTBR T+ Itpr3tf/J m 1.0719 0.1279 1.3231 0.8207
BUB/BnJ f 1.0582 0.107 1.2684 0.848
BUB/BnJ m 0.9916 0.1513 1.2888 0.6944
C3H/HeJ f 0.9381 0.107 1.1483 0.7279
C3H/HeJ m 0.8251 0.1196 1.0601 0.5901
C57BL/10J f 0.8561 0.1128 1.0777 0.6346
C57BL/10J m 0.7284 0.107 0.9386 0.5182
C57BL/6J f 0.8574 0.107 1.0676 0.6472
C57BL/6J m 0.8614 0.107 1.0716 0.6512
C57BLKS/J f 0.8384 0.1128 1.06 0.6169
C57BLKS/J m 0.707 0.1513 1.0042 0.4098
C57BR/cdJ f 1.2238 0.107 1.434 1.0136
C57BR/cdJ m 1.2703 0.107 1.4805 1.0601
C57L/J f 0.94 0.107 1.1502 0.7298
C57L/J m 0.9677 0.107 1.1779 0.7575
C58/J f 0.6038 0.1513 0.901 0.3066
C58/J m 0.955 0.1279 1.2062 0.7038
CAST/EiJ f 0.7556 0.1128 0.9771 0.534
CAST/EiJ m 0.795 0.1196 1.03 0.56
CBA/J f 0.9424 0.1196 1.1774 0.7074
CBA/J m 0.7745 0.1196 1.0095 0.5395
CZECHII/EiJ f 0.7845 0.102 0.9849 0.5842
CZECHII/EiJ m 0.9063 0.1128 1.1279 0.6848
DBA/1J f 0.9206 0.1279 1.1718 0.6694
DBA/1J m 0.8831 0.1196 1.1181 0.6481
DBA/2J f 0.9559 0.1128 1.1774 0.7343
DBA/2J m 0.9064 0.1128 1.128 0.6849
FVB/NJ f 0.9667 0.1196 1.2017 0.7318
FVB/NJ m 0.6472 0.1513 0.9444 0.35
I/LnJ f 0.8225 0.107 1.0327 0.6123
I/LnJ m 1.0899 0.1128 1.3114 0.8683
JF1/MsJ f 0.7835 0.107 0.9937 0.5733
JF1/MsJ m 0.6494 0.1279 0.9006 0.3982
LP/J f 1.3121 0.107 1.5223 1.1019
LP/J m 1.1268 0.0977 1.3187 0.935
MA/MyJ f 0.8837 0.107 1.0939 0.6735
MA/MyJ m 0.7459 0.107 0.9561 0.5357
MOLF/EiJ f 0.5569 0.1279 0.8081 0.3057
MOLF/EiJ m 0.52 0.1128 0.7415 0.2985
MSM/MsJ f 0.9512 0.1513 1.2484 0.654
MSM/MsJ m 1.1156 0.102 1.316 0.9152
NOD/ShiLtJ f 1.233 0.1279 1.4842 0.9818
NOD/ShiLtJ m 1.5002 0.1692 1.8326 1.1679
NON/ShiLtJ f 0.8793 0.107 1.0895 0.6691
NON/ShiLtJ m 1.3194 0.0977 1.5113 1.1276
NZB/BlNJ f 0.9918 0.0977 1.1837 0.8
NZB/BlNJ m 0.9903 0.1128 1.2119 0.7688
NZW/LacJ f 0.9511 0.1128 1.1727 0.7296
NZW/LacJ m 0.9218 0.1196 1.1567 0.6868
PERA/EiJ f 1.0368 0.1128 1.2583 0.8152
PERA/EiJ m 0.9945 0.1196 1.2295 0.7595
PL/J f 0.9181 0.107 1.1283 0.7079
PL/J m 0.7116 0.1513 1.0088 0.4144
PWK/PhJ f 1.0499 0.1128 1.2714 0.8283
PWK/PhJ m 0.9481 0.1196 1.1831 0.7131
RIIIS/J f 0.8515 0.1382 1.1228 0.5802
RIIIS/J m 0.8885 0.1196 1.1235 0.6535
SEA/GnJ f 0.826 0.1128 1.0475 0.6045
SEA/GnJ m 1.0706 0.1279 1.3218 0.8194
SJL/J f 0.8384 0.1128 1.06 0.6169
SJL/J m 0.7 0.0977 0.8919 0.5081
SM/J f 0.8872 0.1196 1.1222 0.6523
SM/J m 1.1061 0.1128 1.3277 0.8846
SPRET/EiJ f 1.1242 0.1692 1.4566 0.7919
SPRET/EiJ m 1.1834 0.1513 1.4806 0.8862
SWR/J f 0.816 0.1196 1.051 0.581
SWR/J m 0.795 0.1279 1.0462 0.5438
WSB/EiJ f 1.6826 0.1196 1.9176 1.4476
WSB/EiJ m 0.6774 0.1128 0.899 0.4559


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.677 0.0777 0.8297 0.5244
A/J both 0.5021 0.0777 0.6548 0.3494
BALB/cByJ both 0.8094 0.0786 0.9638 0.655
BALB/cJ both 0.7597 0.0777 0.9124 0.6071
BTBR T+ Itpr3tf/J both 1.056 0.0876 1.228 0.884
BUB/BnJ both 1.0249 0.0927 1.2069 0.8429
C3H/HeJ both 0.8816 0.0803 1.0392 0.724
C57BL/10J both 0.7923 0.0777 0.9449 0.6396
C57BL/6J both 0.8594 0.0757 1.008 0.7108
C57BLKS/J both 0.7727 0.0944 0.9581 0.5874
C57BR/cdJ both 1.247 0.0757 1.3957 1.0984
C57L/J both 0.9538 0.0757 1.1025 0.8052
C58/J both 0.7794 0.0991 0.974 0.5848
CAST/EiJ both 0.7753 0.0822 0.9368 0.6138
CBA/J both 0.8584 0.0846 1.0246 0.6923
CZECHII/EiJ both 0.8454 0.076 0.9948 0.6961
DBA/1J both 0.9018 0.0876 1.0738 0.7299
DBA/2J both 0.9312 0.0798 1.0878 0.7745
FVB/NJ both 0.807 0.0965 0.9964 0.6175
I/LnJ both 0.9562 0.0777 1.1089 0.8035
JF1/MsJ both 0.7165 0.0834 0.8802 0.5527
LP/J both 1.2195 0.0724 1.3618 1.0772
MA/MyJ both 0.8148 0.0757 0.9634 0.6662
MOLF/EiJ both 0.5384 0.0853 0.7059 0.371
MSM/MsJ both 1.0334 0.0913 1.2127 0.8542
NOD/ShiLtJ both 1.3666 0.1061 1.5749 1.1583
NON/ShiLtJ both 1.0994 0.0724 1.2416 0.9571
NZB/BlNJ both 0.9911 0.0746 1.1376 0.8445
NZW/LacJ both 0.9364 0.0822 1.0979 0.775
PERA/EiJ both 1.0156 0.0822 1.1771 0.8542
PL/J both 0.8148 0.0927 0.9969 0.6328
PWK/PhJ both 0.999 0.0822 1.1605 0.8375
RIIIS/J both 0.87 0.0914 1.0495 0.6905
SEA/GnJ both 0.9483 0.0853 1.1158 0.7808
SJL/J both 0.7692 0.0746 0.9158 0.6227
SM/J both 0.9967 0.0822 1.1582 0.8352
SPRET/EiJ both 1.1538 0.1135 1.3767 0.9309
SWR/J both 0.8055 0.0876 0.9775 0.6335
WSB/EiJ both 1.18 0.0822 1.3415 1.0186




  GWAS USING LINEAR MIXED MODELS