Project measure / variable:   Donahue2   elastic_modulus

ID, description, units MPD:17230   elastic_modulus   estimated elastic modulus   [N/mm2]  
Data set, strains Donahue2   inbred   10 strains     sex: both     age: 16wks
Procedure biomechanical test
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  STRAIN COMPARISON PLOT
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Donahue2 - estimated elastic modulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means4.30   N/mm2 3.56   N/mm2
Median of the strain means4.29   N/mm2 3.53   N/mm2
SD of the strain means± 0.671 ± 0.940
Coefficient of variation (CV)0.156 0.264
Min–max range of strain means3.29   –   5.30   N/mm2 2.18   –   5.63   N/mm2
Mean sample size per strain9.9   mice 10.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 27.6525 27.6525 77.3014 < 0.0001
strain 9 111.5025 12.3892 34.6334 < 0.0001
sex:strain 9 16.4083 1.8231 5.0965 < 0.0001
Residuals 189 67.6097 0.3577


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 4.23 0.35   10 0.111 0.0826 3.66, 4.86 -0.11
129S1/SvImJ m 4.01 0.553   14 0.148 0.138 3.1, 4.89 0.48
BALB/cJ f 4.42 0.442   10 0.14 0.0999 3.92, 5.38 0.17
BALB/cJ m 3.62 0.559   10 0.177 0.154 2.84, 4.56 0.06
C3H/HeJ f 5.3 0.881   9 0.294 0.166 4.2, 7.34 1.49
C3H/HeJ m 4.04 0.83   10 0.262 0.206 2.82, 5.13 0.51
C57BL/6J f 3.29 0.215   10 0.0681 0.0655 2.83, 3.55 -1.51
C57BL/6J m 2.18 0.354   12 0.102 0.163 1.77, 2.88 -1.47
C58/J f 3.7 0.648   10 0.205 0.175 2.75, 4.69 -0.9
C58/J m 3.04 0.288   10 0.0912 0.0951 2.6, 3.6 -0.55
FVB/NJ f 3.56 0.512   10 0.162 0.144 2.48, 4.32 -1.11
FVB/NJ m 2.62 0.344   9 0.115 0.131 2.17, 3.28 -1.0
NZB/BlNJ f 4.12 0.376   11 0.113 0.0912 3.27, 4.57 -0.27
NZB/BlNJ m 3.23 0.311   13 0.0863 0.0962 2.67, 3.67 -0.35
PWK/PhJ f 4.99 0.757   12 0.218 0.152 3.52, 6.02 1.02
PWK/PhJ m 5.63 0.837   11 0.252 0.149 4.34, 6.86 2.2
SJL/J f 4.35 0.599   8 0.212 0.138 2.97, 5.01 0.07
SJL/J m 3.44 0.496   11 0.15 0.144 2.6, 4.06 -0.13
SWR/J f 5.07 0.944   9 0.315 0.186 3.6, 6.51 1.14
SWR/J m 3.79 0.939   10 0.297 0.248 2.06, 5.2 0.24


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 4.233 0.1891 4.6061 3.8599
129S1/SvImJ m 4.01 0.1598 4.3253 3.6947
BALB/cJ f 4.42 0.1891 4.7931 4.0469
BALB/cJ m 3.621 0.1891 3.9941 3.2479
C3H/HeJ f 5.3011 0.1994 5.6944 4.9078
C3H/HeJ m 4.035 0.1891 4.4081 3.6619
C57BL/6J f 3.29 0.1891 3.6631 2.9169
C57BL/6J m 2.1783 0.1727 2.5189 1.8378
C58/J f 3.704 0.1891 4.0771 3.3309
C58/J m 3.035 0.1891 3.4081 2.6619
FVB/NJ f 3.558 0.1891 3.9311 3.1849
FVB/NJ m 2.6189 0.1994 3.0122 2.2256
NZB/BlNJ f 4.1209 0.1803 4.4766 3.7652
NZB/BlNJ m 3.2338 0.1659 3.5611 2.9066
PWK/PhJ f 4.9908 0.1727 5.3314 4.6503
PWK/PhJ m 5.6327 0.1803 5.9885 5.277
SJL/J f 4.3513 0.2115 4.7684 3.9341
SJL/J m 3.4427 0.1803 3.7985 3.087
SWR/J f 5.0656 0.1994 5.4588 4.6723
SWR/J m 3.788 0.1891 4.1611 3.4149


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 4.1215 0.1238 4.3657 3.8773
BALB/cJ both 4.0205 0.1337 4.2843 3.7567
C3H/HeJ both 4.6681 0.1374 4.9391 4.397
C57BL/6J both 2.7342 0.128 2.9867 2.4816
C58/J both 3.3695 0.1337 3.6333 3.1057
FVB/NJ both 3.0884 0.1374 3.3595 2.8174
NZB/BlNJ both 3.6774 0.1225 3.919 3.4357
PWK/PhJ both 5.3118 0.1248 5.558 5.0655
SJL/J both 3.897 0.139 4.1711 3.6229
SWR/J both 4.4268 0.1374 4.6978 4.1557




  GWAS USING LINEAR MIXED MODELS