Project measure / variable:   Donahue2   femur_peak_extension

ID, description, units MPD:17207   femur_peak_extension   displacement at peak load   [mm]  
Data set, strains Donahue2   inbred   10 strains     sex: both     age: 16wks
Procedure biomechanical test
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  STRAIN COMPARISON PLOT
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Donahue2 - displacement at peak load



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means0.252   mm 0.279   mm
Median of the strain means0.254   mm 0.277   mm
SD of the strain means± 0.0385 ± 0.0254
Coefficient of variation (CV)0.153 0.0913
Min–max range of strain means0.186   –   0.321   mm 0.235   –   0.310   mm
Mean sample size per strain10.0   mice 11.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0331 0.0331 14.8047 0.0002
strain 9 0.1898 0.0211 9.4297 < 0.0001
sex:strain 9 0.0228 0.0025 1.1335 0.3409
Residuals 192 0.4294 0.0022


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.186 0.0479   10 0.0151 0.257 0.111, 0.262 -1.71
129S1/SvImJ m 0.246 0.0551   15 0.0142 0.224 0.149, 0.324 -1.28
BALB/cJ f 0.246 0.0306   10 0.00969 0.125 0.207, 0.296 -0.16
BALB/cJ m 0.265 0.0269   10 0.00852 0.102 0.225, 0.311 -0.53
C3H/HeJ f 0.25 0.0372   9 0.0124 0.149 0.202, 0.311 -0.05
C3H/HeJ m 0.28 0.0476   11 0.0144 0.17 0.189, 0.352 0.06
C57BL/6J f 0.269 0.0407   10 0.0129 0.151 0.224, 0.358 0.44
C57BL/6J m 0.31 0.0804   12 0.0232 0.259 0.196, 0.438 1.23
C58/J f 0.258 0.056   10 0.0177 0.217 0.192, 0.346 0.16
C58/J m 0.273 0.0561   10 0.0177 0.206 0.176, 0.354 -0.22
FVB/NJ f 0.293 0.0535   11 0.0161 0.182 0.193, 0.354 1.06
FVB/NJ m 0.299 0.059   9 0.0197 0.198 0.225, 0.398 0.8
NZB/BlNJ f 0.321 0.0414   11 0.0125 0.129 0.241, 0.39 1.79
NZB/BlNJ m 0.308 0.0414   13 0.0115 0.134 0.211, 0.385 1.16
PWK/PhJ f 0.212 0.0267   12 0.0077 0.126 0.162, 0.25 -1.04
PWK/PhJ m 0.235 0.0352   11 0.0106 0.15 0.187, 0.311 -1.71
SJL/J f 0.228 0.0305   8 0.0108 0.133 0.193, 0.275 -0.62
SJL/J m 0.273 0.0346   11 0.0104 0.126 0.225, 0.334 -0.22
SWR/J f 0.257 0.0303   9 0.0101 0.118 0.218, 0.294 0.13
SWR/J m 0.297 0.0621   10 0.0196 0.209 0.205, 0.425 0.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.1864 0.015 0.2159 0.1569
129S1/SvImJ m 0.2459 0.0122 0.27 0.2218
BALB/cJ f 0.2457 0.015 0.2752 0.2162
BALB/cJ m 0.2652 0.015 0.2947 0.2357
C3H/HeJ f 0.2501 0.0158 0.2812 0.219
C3H/HeJ m 0.2802 0.0143 0.3083 0.2521
C57BL/6J f 0.2693 0.015 0.2988 0.2398
C57BL/6J m 0.3101 0.0137 0.337 0.2832
C58/J f 0.2583 0.015 0.2878 0.2288
C58/J m 0.2726 0.015 0.3021 0.2431
FVB/NJ f 0.2932 0.0143 0.3213 0.2651
FVB/NJ m 0.2988 0.0158 0.3299 0.2677
NZB/BlNJ f 0.3213 0.0143 0.3494 0.2931
NZB/BlNJ m 0.3082 0.0131 0.334 0.2823
PWK/PhJ f 0.2118 0.0137 0.2388 0.1849
PWK/PhJ m 0.2345 0.0143 0.2627 0.2064
SJL/J f 0.2283 0.0167 0.2612 0.1953
SJL/J m 0.2732 0.0143 0.3013 0.2451
SWR/J f 0.2567 0.0158 0.2878 0.2256
SWR/J m 0.2974 0.015 0.3269 0.2679


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.2161 0.0097 0.2352 0.1971
BALB/cJ both 0.2555 0.0106 0.2763 0.2346
C3H/HeJ both 0.2651 0.0106 0.2861 0.2442
C57BL/6J both 0.2897 0.0101 0.3097 0.2697
C58/J both 0.2655 0.0106 0.2863 0.2446
FVB/NJ both 0.296 0.0106 0.3169 0.275
NZB/BlNJ both 0.3147 0.0097 0.3338 0.2956
PWK/PhJ both 0.2232 0.0099 0.2427 0.2037
SJL/J both 0.2507 0.011 0.2724 0.229
SWR/J both 0.277 0.0109 0.2985 0.2556




  GWAS USING LINEAR MIXED MODELS