Project measure / variable:   Donahue2   femur_peak_load

ID, description, units MPD:17206   femur_peak_load   maximum load on load-displacement curve   [N]  
Data set, strains Donahue2   inbred   10 strains     sex: both     age: 16wks
Procedure biomechanical test
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  STRAIN COMPARISON PLOT
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Donahue2 - maximum load on load-displacement curve



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means26.3   N 28.8   N
Median of the strain means25.1   N 27.1   N
SD of the strain means± 6.08 ± 7.68
Coefficient of variation (CV)0.231 0.267
Min–max range of strain means19.0   –   39.7   N 18.6   –   45.2   N
Mean sample size per strain10.0   mice 11.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 435.027 435.027 52.878 < 0.0001
strain 9 8708.8431 967.6492 117.6188 < 0.0001
sex:strain 9 419.6372 46.6264 5.6675 < 0.0001
Residuals 192 1579.5826 8.227


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 23.7 4.01   10 1.27 0.169 18.2, 30.9 -0.43
129S1/SvImJ m 28.0 4.0   15 1.03 0.143 23.4, 36.4 -0.1
BALB/cJ f 30.3 2.18   10 0.69 0.0721 25.5, 32.9 0.65
BALB/cJ m 32.2 1.68   10 0.532 0.0523 29.9, 35.2 0.45
C3H/HeJ f 39.7 2.69   9 0.896 0.0676 35.2, 42.8 2.2
C3H/HeJ m 45.2 4.22   11 1.27 0.0934 36.9, 50.8 2.14
C57BL/6J f 20.9 2.71   10 0.856 0.129 17.9, 25.2 -0.89
C57BL/6J m 26.3 2.42   12 0.698 0.0921 21.7, 29.9 -0.32
C58/J f 24.0 2.08   10 0.658 0.0867 21.4, 27.2 -0.38
C58/J m 23.6 2.79   10 0.883 0.118 19.4, 28.2 -0.67
FVB/NJ f 26.9 2.02   11 0.61 0.0754 23.6, 29.7 0.1
FVB/NJ m 24.2 2.13   9 0.71 0.0882 21.6, 27.5 -0.59
NZB/BlNJ f 30.8 2.92   11 0.881 0.095 26.7, 37.4 0.74
NZB/BlNJ m 37.1 3.42   13 0.947 0.092 31.0, 43.1 1.09
PWK/PhJ f 19.0 2.41   12 0.697 0.127 15.3, 22.7 -1.2
PWK/PhJ m 18.6 2.74   11 0.826 0.147 13.0, 22.2 -1.32
SJL/J f 26.3 3.17   8 1.12 0.121 22.0, 32.0 0.0
SJL/J m 28.3 2.1   11 0.634 0.0742 25.8, 31.1 -0.06
SWR/J f 21.6 1.25   9 0.417 0.0579 20.5, 24.2 -0.78
SWR/J m 24.1 3.3   10 1.04 0.137 19.8, 29.7 -0.61


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 23.74 0.907 25.529 21.951
129S1/SvImJ m 28.0333 0.7406 29.4941 26.5726
BALB/cJ f 30.26 0.907 32.049 28.471
BALB/cJ m 32.18 0.907 33.969 30.391
C3H/HeJ f 39.7333 0.9561 41.6191 37.8475
C3H/HeJ m 45.2 0.8648 46.9058 43.4942
C57BL/6J f 20.93 0.907 22.719 19.141
C57BL/6J m 26.25 0.828 27.8831 24.6169
C58/J f 23.99 0.907 25.779 22.201
C58/J m 23.63 0.907 25.419 21.841
FVB/NJ f 26.8545 0.8648 28.5603 25.1488
FVB/NJ m 24.1667 0.9561 26.0525 22.2809
NZB/BlNJ f 30.7545 0.8648 32.4603 29.0488
NZB/BlNJ m 37.1385 0.7955 38.7075 35.5694
PWK/PhJ f 18.9833 0.828 20.6165 17.3502
PWK/PhJ m 18.6364 0.8648 20.3421 16.9306
SJL/J f 26.3375 1.0141 28.3377 24.3373
SJL/J m 28.3091 0.8648 30.0149 26.6033
SWR/J f 21.6 0.9561 23.4858 19.7142
SWR/J m 24.09 0.907 25.879 22.301


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 25.8867 0.5855 27.0415 24.7319
BALB/cJ both 31.22 0.6414 32.485 29.955
C3H/HeJ both 42.4667 0.6446 43.7381 41.1953
C57BL/6J both 23.59 0.6141 24.8012 22.3788
C58/J both 23.81 0.6414 25.075 22.545
FVB/NJ both 25.5106 0.6446 26.782 24.2392
NZB/BlNJ both 33.9465 0.5875 35.1053 32.7877
PWK/PhJ both 18.8098 0.5986 19.9906 17.6291
SJL/J both 27.3233 0.6664 28.6377 26.0089
SWR/J both 22.845 0.6589 24.1447 21.5453




  GWAS USING LINEAR MIXED MODELS