Project measure / variable:   CSNA03   reinstatement_inf_in_s1

ID, description, units MPD:110220   reinstatement_inf_in_s1   reinstatement, number of infusions (intravenous self administration), founders   [n]  session 1  
cocaine study
Data set, strains CSNA03   inbred w/CC8   7 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - reinstatement, number of infusions (intravenous self administration), founders session 1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means53.72   n 37.276   n
Median of the strain means52.57   n 32.231   n
SD of the strain means± 24.716 ± 7.8621
Coefficient of variation (CV)0.4601 0.2109
Min–max range of strain means28.4   –   100.0   n 29.0   –   46.333   n
Mean sample size per strain7.6   mice 7.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3001.1275 3001.1275 3.8397 0.0533
strain 5 8466.153 1693.2306 2.1664 0.0651
sex:strain 5 5452.8587 1090.5717 1.3953 0.234
Residuals 87 67999.5174 781.6036


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 34.333 24.125   9 8.0416 0.7027 -0.78
A/J m 29.0 30.364   7 11.477 1.0471 -1.05
C57BL/6J f 69.42 43.393   12 12.527 0.6251 8.0, 160.0 0.64
C57BL/6J m 32.231 20.335   13 5.64 0.6309 2.0, 84.0 -0.64
CAST/EiJ f 100.0 0.0   1   0.0 0.0 100.0, 100.0 1.87
CAST/EiJ m 46.0 38.184   2   27.0 0.8301 19.0, 73.0 1.11
NOD/ShiLtJ f 37.636 31.255   11 9.4236 0.8304 3.0, 104.0 -0.65
NOD/ShiLtJ m 32.167 21.075   6 8.6039 0.6552 8.0, 64.0 -0.65
NZO/HlLtJ f 28.4 20.818   10 6.5831 0.733 5.0, 65.0 -1.02
NZO/HlLtJ m 30.8 16.096   10 5.0899 0.5226 6.0, 59.0 -0.82
PWK/PhJ f 52.57 25.198   7 9.524 0.4793 20.0, 93.0 -0.05
PWK/PhJ m 46.333 24.279   6 9.9118 0.524 10.0, 72.0 1.15
WSB/EiJ f 53.67 45.369   3 26.194 0.8454 2.0, 87.0 0.0
WSB/EiJ m 44.4 27.574   5 12.331 0.621 13.0, 78.0 0.91


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 34.3333333333 9.3190584208 52.8559710271 15.8106956396
A/J m 29.0 10.5668190149 50.002696984 7.997303016
C57BL/6J f 69.4166666667 8.0705413318 85.4577414546 53.3755918788
C57BL/6J m 32.2307692308 7.753925302 47.6425353758 16.8190030858
NOD/ShiLtJ f 37.6363636364 8.4294055039 54.3907198249 20.8820074478
NOD/ShiLtJ m 32.1666666667 11.4134690071 54.8521721868 9.4811611466
NZO/HlLtJ f 28.4 8.8408350774 45.9721170159 10.8278829841
NZO/HlLtJ m 30.8 8.8408350774 48.3721170159 13.2278829841
PWK/PhJ f 52.5714285714 10.5668190149 73.5741255554 31.5687315874
PWK/PhJ m 46.3333333333 11.4134690071 69.0188388534 23.6478278132
WSB/EiJ f 53.6666666667 16.1410826635 85.7488162425 21.5845170909
WSB/EiJ m 44.4 12.5028288691 69.2507262035 19.5492737965


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 31.6666666667 7.0445460099 45.668464656 17.6648686773
C57BL/6J both 50.8237179487 5.5959135755 61.9462021144 39.7012337831
NOD/ShiLtJ both 34.9015151515 7.0944018762 49.0024070736 20.8006232294
NZO/HlLtJ both 29.6 6.2514144346 42.0253631018 17.1746368982
PWK/PhJ both 49.4523809524 7.7769682214 64.9099473949 33.9948145098
WSB/EiJ both 49.0333333333 10.2085170235 69.3238663121 28.7428003546




  GWAS USING LINEAR MIXED MODELS