Project measure / variable:   CSNA03   reinstatement_inactive_in_s2

ID, description, units MPD:110219   reinstatement_inactive_in_s2   reinstatement, inactive lever presses (intravenous self administration), founders   [n]  session 2  
cocaine study
Data set, strains CSNA03   inbred w/CC8   7 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - reinstatement, inactive lever presses (intravenous self administration), founders session 2



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means24.022   n 32.611   n
Median of the strain means26.455   n 24.8   n
SD of the strain means± 11.268 ± 20.673
Coefficient of variation (CV)0.4691 0.6339
Min–max range of strain means7.3333   –   37.0   n 11.615   –   63.0   n
Mean sample size per strain7.6   mice 7.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 235.8401 235.8401 0.1811 0.6715
strain 5 4925.1325 985.0265 0.7563 0.5838
sex:strain 5 12058.8425 2411.7685 1.8517 0.1112
Residuals 87 113316.7304 1302.4912


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 7.3333 13.096   9 4.3653 1.7858 -1.48
A/J m 50.43 92.84   7 35.092 1.8411 0.86
C57BL/6J f 31.583 32.759   12 9.4568 1.0372 1.0, 105.0 0.67
C57BL/6J m 11.615 8.94   13 2.4795 0.7697 -1.02
CAST/EiJ f 30.0 0.0   1   0.0 0.0 30.0, 30.0 0.53
CAST/EiJ m 63.0 86.27   2   61.0 1.3693 2.0, 124.0 1.47
NOD/ShiLtJ f 26.455 42.113   11 12.697 1.5919 0.22
NOD/ShiLtJ m 14.667 12.061   6 4.9239 0.8223 4.0, 31.0 -0.87
NZO/HlLtJ f 9.5 9.2646   10 2.9297 0.9752 -1.29
NZO/HlLtJ m 16.1 21.687   10 6.858 1.347 1.0, 73.0 -0.8
PWK/PhJ f 26.286 17.124   7 6.4723 0.6515 11.0, 56.0 0.2
PWK/PhJ m 47.667 54.23   6 22.14 1.1377 5.0, 146.0 0.73
WSB/EiJ f 37.0 40.927   3 23.629 1.1061 2.0, 82.0 1.15
WSB/EiJ m 24.8 32.322   5 14.455 1.3033 3.0, 82.0 -0.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 7.3333333333 12.030014103 31.2442889921 -16.5776223254
A/J m 50.4285714286 13.6407538222 77.5410466927 23.3160961644
C57BL/6J f 31.5833333333 10.4182978211 52.2908283626 10.8758383041
C57BL/6J m 11.6153846154 10.0095767753 31.5105023092 -8.2797330784
NOD/ShiLtJ f 26.4545454545 10.8815571825 48.082818627 4.8262722821
NOD/ShiLtJ m 14.6666666667 14.7336980754 43.9514869798 -14.6181536465
NZO/HlLtJ f 9.5 11.4126734548 32.1839242739 -13.1839242739
NZO/HlLtJ m 16.1 11.4126734548 38.7839242739 -6.5839242739
PWK/PhJ f 26.2857142857 13.6407538222 53.3981895498 -0.8267609784
PWK/PhJ m 47.6666666667 14.7336980754 76.9514869798 18.3818463535
WSB/EiJ f 37.0 20.8365956422 78.4149900585 -4.4149900585
WSB/EiJ m 24.8 16.1399575828 56.879913356 -7.279913356


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 28.880952381 9.0938358815 46.9559358904 10.8059688715
C57BL/6J both 21.5993589744 7.2237898071 35.9574234194 7.2412945293
NOD/ShiLtJ both 20.5606060606 9.1581950418 38.76351037 2.3577017512
NZO/HlLtJ both 12.8 8.0699787914 28.839956678 -3.239956678
PWK/PhJ both 36.9761904762 10.0393229828 56.9304319784 17.0219489739
WSB/EiJ both 30.9 13.1782201826 57.0931395716 4.7068604284




  GWAS USING LINEAR MIXED MODELS