Project measure / variable:   CSNA03   reinstatement_inactive_in_s1

ID, description, units MPD:110218   reinstatement_inactive_in_s1   reinstatement, inactive lever presses (intravenous self administration), founders   [n]  session 1  
cocaine study
Data set, strains CSNA03   inbred w/CC8   7 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - reinstatement, inactive lever presses (intravenous self administration), founders session 1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means35.719   n 36.121   n
Median of the strain means34.0   n 22.5   n
SD of the strain means± 26.773 ± 41.964
Coefficient of variation (CV)0.7495 1.1618
Min–max range of strain means10.222   –   89.0   n 10.846   –   129.6   n
Mean sample size per strain7.6   mice 7.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1115.406 1115.406 0.1547 0.695
strain 5 24666.3063 4933.2613 0.6844 0.6365
sex:strain 5 62440.4788 12488.0958 1.7325 0.1356
Residuals 87 627095.9907 7207.9999


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 10.222 8.0743   9 2.6914 0.7899 -0.95
A/J m 129.6 307.0   7 116.0 2.3691 2.23
C57BL/6J f 42.5 46.615   12 13.457 1.0968 0.25
C57BL/6J m 10.846 9.856   13 2.7336 0.9087 -0.6
CAST/EiJ f 89.0 0.0   1   0.0 0.0 89.0, 89.0 1.99
CAST/EiJ m 32.0 39.598   2   28.0 1.2374 4.0, 60.0 -0.1
NOD/ShiLtJ f 34.0 48.924   11 14.751 1.439 -0.06
NOD/ShiLtJ m 15.5 13.308   6 5.4329 0.8586 2.0, 37.0 -0.49
NZO/HlLtJ f 10.6 7.8627   10 2.4864 0.7418 1.0, 22.0 -0.94
NZO/HlLtJ m 13.6 12.501   10 3.9531 0.9192 3.0, 37.0 -0.54
PWK/PhJ f 24.714 12.566   7 4.7495 0.5085 11.0, 47.0 -0.41
PWK/PhJ m 22.5 11.327   6 4.6242 0.5034 6.0, 37.0 -0.32
WSB/EiJ f 39.0 45.211   3 26.102 1.1592 1.0, 89.0 0.12
WSB/EiJ m 28.8 30.327   5 13.562 1.053 3.0, 77.0 -0.17


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 10.2222222222 28.2999801597 66.4714971564 -46.0270527119
A/J m 129.5714285714 32.0891612617 193.3521112444 65.7907458985
C57BL/6J f 42.5 24.5085017449 91.2133010374 -6.2133010374
C57BL/6J m 10.8461538462 23.5470068216 57.6483796114 -35.9560719191
NOD/ShiLtJ f 34.0 25.5982952084 84.8793835508 -16.8793835508
NOD/ShiLtJ m 15.5 34.660255561 84.3910109951 -53.3910109951
NZO/HlLtJ f 10.6 26.8477185126 63.9627476575 -42.7627476575
NZO/HlLtJ m 13.6 26.8477185126 66.9627476575 -39.7627476575
PWK/PhJ f 24.7142857143 32.0891612617 88.4949683872 -39.0663969586
PWK/PhJ m 22.5 34.660255561 91.3910109951 -46.3910109951
WSB/EiJ f 39.0 49.0170034897 136.4266020749 -58.4266020749
WSB/EiJ m 28.8 37.9684076393 104.2663214627 -46.6663214627


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 69.8968253968 21.3927741744 112.4172805121 27.3763702815
C57BL/6J both 26.6730769231 16.9935884088 60.4496739784 -7.1035201322
NOD/ShiLtJ both 24.75 21.5441757392 67.5713821193 -18.0713821193
NZO/HlLtJ both 12.1 18.9842038197 49.8331607314 -25.6331607314
PWK/PhJ both 23.6071428571 23.616983222 70.5484542953 -23.3341685811
WSB/EiJ both 33.9 31.0010750208 95.5179934495 -27.7179934495




  GWAS USING LINEAR MIXED MODELS