Project measure / variable:   CSNA03   extinction_inactive_in_s7

ID, description, units MPD:110213   extinction_inactive_in_s7   extinction, inactive lever presses (intravenous self administration), founders   [n]  session 7  
cocaine study
Data set, strains CSNA03   inbred w/CC8   7 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, inactive lever presses (intravenous self administration), founders session 7



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means30.926   n 20.917   n
Median of the strain means30.636   n 21.5   n
SD of the strain means± 18.249 ± 14.136
Coefficient of variation (CV)0.5901 0.6758
Min–max range of strain means9.8   –   59.78   n 5.7273   –   49.429   n
Mean sample size per strain6.7   mice 6.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2054.6102 2054.6102 1.222 0.2723
strain 5 10417.4926 2083.4985 1.2391 0.2989
sex:strain 5 13943.8158 2788.7632 1.6586 0.1544
Residuals 79 132831.3781 1681.4098


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 15.429 15.799   7 5.9716 1.024 1.0, 46.0 -0.85
A/J m 49.429 84.06   7 31.771 1.7006 2.02
C57BL/6J f 30.636 40.532   11 12.221 1.323 5.0, 127.0 -0.02
C57BL/6J m 5.7273 6.7096   11 2.023 1.1715 -1.07
CAST/EiJ f 43.0 0.0   1   0.0 0.0 43.0, 43.0 0.66
CAST/EiJ m 21.5 28.991   2   20.5 1.3484 1.0, 42.0 0.04
NOD/ShiLtJ f 59.78 82.61   9 27.538 1.382 1.58
NOD/ShiLtJ m 14.333 13.201   6 5.3893 0.921 1.0, 37.0 -0.47
NZO/HlLtJ f 9.8 8.3772   10 2.6491 0.8548 -1.16
NZO/HlLtJ m 10.6 10.362   10 3.2769 0.9776 2.0, 35.0 -0.73
PWK/PhJ f 16.167 10.147   6 4.1426 0.6277 6.0, 33.0 -0.81
PWK/PhJ m 21.833 30.116   6 12.295 1.3794 2.0, 82.0 0.06
WSB/EiJ f 41.667 63.71   3 36.78 1.5289 0.59
WSB/EiJ m 23.0 21.342   5 9.5446 0.9279 5.0, 55.0 0.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 15.4285714286 15.4984324043 46.277429466 -15.4202866089
A/J m 49.4285714286 15.4984324043 80.277429466 18.5797133911
C57BL/6J f 30.6363636364 12.3634720371 55.2452391518 6.0274881209
C57BL/6J m 5.7272727273 12.3634720371 30.3361482427 -18.8816027882
NOD/ShiLtJ f 59.7777777778 13.6683326177 86.9839133102 32.5716422453
NOD/ShiLtJ m 14.3333333333 16.740220274 47.6539082971 -18.9872416304
NZO/HlLtJ f 9.8 12.9669188666 35.6100063842 -16.0100063842
NZO/HlLtJ m 10.6 12.9669188666 36.4100063842 -15.2100063842
PWK/PhJ f 16.1666666667 16.740220274 49.4872416304 -17.1539082971
PWK/PhJ m 21.8333333333 16.740220274 55.1539082971 -11.4872416304
WSB/EiJ f 41.6666666667 23.6742465487 88.7890756865 -5.4557423532
WSB/EiJ m 23.0 18.3379925234 59.5008610734 -13.5008610734


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 32.4285714286 10.9590466509 54.2420081387 10.6151347184
C57BL/6J both 18.1818181818 8.7422949165 35.5829209362 0.7807154274
NOD/ShiLtJ both 37.0555555556 10.8057657222 58.563894209 15.5472169021
NZO/HlLtJ both 10.2 9.1689962617 28.4504305367 -8.0504305367
PWK/PhJ both 19.0 11.8371232743 42.5612045099 -4.5612045099
WSB/EiJ both 32.3333333333 14.9729081964 62.1361616007 2.530505066




  GWAS USING LINEAR MIXED MODELS