Project measure / variable:   CSNA03   extinction_inactive_in_s6

ID, description, units MPD:110212   extinction_inactive_in_s6   extinction, inactive lever presses (intravenous self administration), founders   [n]  session 6  
cocaine study
Data set, strains CSNA03   inbred w/CC8   7 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, inactive lever presses (intravenous self administration), founders session 6



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means28.272   n 26.988   n
Median of the strain means34.333   n 15.833   n
SD of the strain means± 17.353 ± 26.865
Coefficient of variation (CV)0.6138 0.9954
Min–max range of strain means5.1   –   49.2   n 9.9   –   85.86   n
Mean sample size per strain6.6   mice 6.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 39.7103 39.7103 0.009 0.9247
strain 5 14972.6271 2994.5254 0.6787 0.6409
sex:strain 5 29728.6546 5945.7309 1.3476 0.2532
Residuals 79 348563.9091 4412.2014


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 10.571 14.022   7 5.2999 1.3264 -1.02
A/J m 85.86 190.3   7 71.94 2.2169 2.19
C57BL/6J f 49.2 98.88   10 31.268 2.0097 2.0, 324.0 1.21
C57BL/6J m 9.9091 10.368   11 3.126 1.0463 -0.64
CAST/EiJ f 46.0 0.0   1   0.0 0.0 46.0, 46.0 1.02
CAST/EiJ m 29.5 27.577   2   19.5 0.9348 10.0, 49.0 0.09
NOD/ShiLtJ f 35.3 58.89   10 18.624 1.6684 0.4
NOD/ShiLtJ m 15.833 21.236   6 8.6696 1.3412 -0.42
NZO/HlLtJ f 5.1 4.3576   10 1.378 0.8544 -1.34
NZO/HlLtJ m 9.9 7.3704   10 2.3307 0.7445 -0.64
PWK/PhJ f 17.4 13.088   5 5.8532 0.7522 6.0, 39.0 -0.63
PWK/PhJ m 15.714 11.926   7 4.5077 0.759 5.0, 40.0 -0.42
WSB/EiJ f 34.333 43.097   3 24.882 1.2552 1.0, 83.0 0.35
WSB/EiJ m 22.2 19.791   5 8.851 0.8915 1.0, 43.0 -0.18


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 10.5714285714 25.1060646654 60.5438002628 -39.40094312
A/J m 85.8571428571 25.1060646654 135.8295145485 35.8847711658
C57BL/6J f 49.2 21.0052407292 91.0098858253 7.3901141747
C57BL/6J m 9.9090909091 20.0277112133 49.7732529041 -29.9550710859
NOD/ShiLtJ f 35.3 21.0052407292 77.1098858253 -6.5098858253
NOD/ShiLtJ m 15.8333333333 27.1176491757 69.809663836 -38.1429971694
NZO/HlLtJ f 5.1 21.0052407292 46.9098858253 -36.7098858253
NZO/HlLtJ m 9.9 21.0052407292 51.7098858253 -31.9098858253
PWK/PhJ f 17.4 29.7058963201 76.5281075754 -41.7281075754
PWK/PhJ m 15.7142857143 25.1060646654 65.6866574057 -34.2580859771
WSB/EiJ f 34.3333333333 38.3501472439 110.6673919774 -42.0007253107
WSB/EiJ m 22.2 29.7058963201 81.3281075754 -36.9281075754


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 48.2142857143 17.7526685738 83.5500886092 12.8784828193
C57BL/6J both 29.5545454545 14.5114554278 58.4388749616 0.6702159475
NOD/ShiLtJ both 25.5666666667 17.1507072369 59.704295492 -8.5709621587
NZO/HlLtJ both 7.5 14.85294816 37.0640537877 -22.0640537877
PWK/PhJ both 16.5571428571 19.4470740676 55.2655755234 -22.1512898091
WSB/EiJ both 28.2666666667 24.2547627787 76.5445643387 -20.0112310054




  GWAS USING LINEAR MIXED MODELS