Project measure / variable:   CSNA03   extinction_inactive_in_s4

ID, description, units MPD:110210   extinction_inactive_in_s4   extinction, inactive lever presses (intravenous self administration), founders   [n]  session 4  
cocaine study
Data set, strains CSNA03   inbred w/CC8   7 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, inactive lever presses (intravenous self administration), founders session 4



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means27.833   n 16.165   n
Median of the strain means17.333   n 8.4545   n
SD of the strain means± 20.124 ± 17.418
Coefficient of variation (CV)0.723 1.0775
Min–max range of strain means10.1   –   63.0   n 5.6   –   55.0   n
Mean sample size per strain7.1   mice 6.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1625.4452 1625.4452 0.9468 0.3334
strain 5 9091.2351 1818.247 1.0591 0.3891
sex:strain 5 13034.4145 2606.8829 1.5185 0.1931
Residuals 82 140770.618 1716.7149


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 13.667 23.914   6 9.7627 1.7498 -0.7
A/J m 55.0 85.55   7 32.333 1.5554 2.23
C57BL/6J f 42.083 68.52   12 19.781 1.6283 0.71
C57BL/6J m 8.4545 7.7893   11 2.3486 0.9213 -0.44
CAST/EiJ f 63.0 0.0   1   0.0 0.0 63.0, 63.0 1.75
CAST/EiJ m 8.0 11.314   2   8.0 1.4142 -0.47
NOD/ShiLtJ f 37.364 60.6   11 18.271 1.6218 0.47
NOD/ShiLtJ m 14.0 12.309   5 5.5045 0.8792 6.0, 35.0 -0.12
NZO/HlLtJ f 10.1 11.298   10 3.5729 1.1187 3.0, 39.0 -0.88
NZO/HlLtJ m 8.1 5.4661   10 1.7285 0.6748 1.0, 20.0 -0.46
PWK/PhJ f 11.286 8.8641   7 3.3503 0.7854 2.0, 28.0 -0.82
PWK/PhJ m 14.0 12.179   7 4.6033 0.8699 2.0, 32.0 -0.12
WSB/EiJ f 17.333 28.29   3 16.333 1.6321 1.0, 50.0 -0.52
WSB/EiJ m 5.6 3.1305   5 1.4 0.559 3.0, 11.0 -0.61


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 13.6666666667 16.9150566717 47.3161027986 -19.9827694653
A/J m 55.0 15.6602994554 86.153324317 23.846675683
C57BL/6J f 42.0833333333 11.9607512767 65.8770778054 18.2895888613
C57BL/6J m 8.4545454545 12.4925972743 33.3063010391 -16.3972101301
NOD/ShiLtJ f 37.3636363636 12.4925972743 62.2153919482 12.511880779
NOD/ShiLtJ m 14.0 18.5295162011 50.8611104336 -22.8611104336
NZO/HlLtJ f 10.1 13.1023465579 36.1647411497 -15.9647411497
NZO/HlLtJ m 8.1 13.1023465579 34.1647411497 -17.9647411497
PWK/PhJ f 11.2857142857 15.6602994554 42.4390386027 -19.8676100313
PWK/PhJ m 14.0 15.6602994554 45.153324317 -17.153324317
WSB/EiJ f 17.3333333333 23.9215025534 64.9208222774 -30.2541556107
WSB/EiJ m 5.6 18.5295162011 42.4611104336 -31.2611104336


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 34.3333333333 11.5256683238 57.2615592132 11.4051074534
C57BL/6J both 25.2689393939 8.6476088857 42.4717882251 8.0660905627
NOD/ShiLtJ both 25.6818181818 11.1737186883 47.9099041208 3.4537322429
NZO/HlLtJ both 9.1 9.2647581006 27.5305552168 -9.3305552168
PWK/PhJ both 12.6428571429 11.0735039403 34.6715840239 -9.3858697382
WSB/EiJ both 11.4666666667 15.1292866245 41.5636373049 -18.6303039716




  GWAS USING LINEAR MIXED MODELS