Project measure / variable:   CSNA03   extinction_inactive_in_s3

ID, description, units MPD:110209   extinction_inactive_in_s3   extinction, inactive lever presses (intravenous self administration), founders   [n]  session 3  
cocaine study
Data set, strains CSNA03   inbred w/CC8   7 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, inactive lever presses (intravenous self administration), founders session 3



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means27.296   n 16.514   n
Median of the strain means37.909   n 17.857   n
SD of the strain means± 18.937 ± 5.6202
Coefficient of variation (CV)0.6938 0.3403
Min–max range of strain means4.5   –   48.273   n 9.0769   –   26.429   n
Mean sample size per strain7.0   mice 7.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3838.0104 3838.0104 1.9459 0.1667
strain 5 5213.3638 1042.6728 0.5286 0.754
sex:strain 5 10441.855 2088.371 1.0588 0.3891
Residuals 84 165676.9271 1972.3444


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 8.625 14.242   8 5.0354 1.6513 -0.99
A/J m 26.429 29.938   7 11.316 1.1328 1.76
C57BL/6J f 37.909 54.42   11 16.407 1.4354 0.56
C57BL/6J m 9.0769 6.4351   13 1.7848 0.7089 -1.32
CAST/EiJ f 43.0 0.0   1   0.0 0.0 43.0, 43.0 0.83
CAST/EiJ m 18.5 17.678   2   12.5 0.9555 6.0, 31.0 0.35
NOD/ShiLtJ f 48.273 102.6   11 30.923 2.1246 1.11
NOD/ShiLtJ m 11.833 10.852   6 4.4303 0.9171 1.0, 31.0 -0.83
NZO/HlLtJ f 9.1 9.4334   10 2.9831 1.0366 -0.96
NZO/HlLtJ m 17.9 22.698   10 7.1778 1.2681 1.0, 74.0 0.25
PWK/PhJ f 39.667 56.75   6 23.168 1.4307 5.0, 153.0 0.65
PWK/PhJ m 17.857 12.362   7 4.6723 0.6923 7.0, 38.0 0.24
WSB/EiJ f 4.5 0.70711   2   0.5 0.1571 4.0, 5.0 -1.2
WSB/EiJ m 14.0 11.619   5 5.1962 0.8299 5.0, 33.0 -0.45


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 8.625 15.7016892802 39.8495310904 -22.5995310904
A/J m 26.4285714286 16.7858119086 59.808999258 -6.9518564009
C57BL/6J f 37.9090909091 13.3904456101 64.5374604945 11.2807213237
C57BL/6J m 9.0769230769 12.3174184671 33.5714605128 -15.4176143589
NOD/ShiLtJ f 48.2727272727 13.3904456101 74.9010968581 21.6443576873
NOD/ShiLtJ m 11.8333333333 18.1307490653 47.8883161941 -24.2216495274
NZO/HlLtJ f 9.1 14.0440178368 37.0280696335 -18.8280696335
NZO/HlLtJ m 17.9 14.0440178368 45.8280696335 -10.0280696335
PWK/PhJ f 39.6666666667 18.1307490653 75.7216495274 3.6116838059
PWK/PhJ m 17.8571428571 16.7858119086 51.2375706866 -15.5232849723
WSB/EiJ f 4.5 31.4033785604 66.9490621809 -57.9490621809
WSB/EiJ m 14.0 19.8612404951 53.4962548466 -25.4962548466


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 17.5267857143 11.4924597855 40.380802341 -5.3272309124
C57BL/6J both 23.493006993 9.0970164248 41.583421796 5.40259219
NOD/ShiLtJ both 30.053030303 11.2697392972 52.4641428137 7.6419177923
NZO/HlLtJ both 13.5 9.9306202475 33.2481274233 -6.2481274233
PWK/PhJ both 28.7619047619 12.3540230603 53.3292344457 4.1945750781
WSB/EiJ both 9.25 18.5784893022 46.1953634242 -27.6953634242




  GWAS USING LINEAR MIXED MODELS