Project measure / variable:   CSNA03   extinction_inactive_in_s1

ID, description, units MPD:110207   extinction_inactive_in_s1   extinction, inactive lever presses (intravenous self administration), founders   [n]  session 1  
cocaine study
Data set, strains CSNA03   inbred w/CC8   7 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, inactive lever presses (intravenous self administration), founders session 1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means35.535   n 41.047   n
Median of the strain means30.0   n 24.833   n
SD of the strain means± 18.085 ± 42.849
Coefficient of variation (CV)0.5089 1.0439
Min–max range of strain means19.778   –   72.9   n 7.8   –   134.3   n
Mean sample size per strain7.1   mice 6.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 202.3197 202.3197 0.0238 0.8777
strain 5 34124.4307 6824.8861 0.8035 0.5504
sex:strain 5 61613.1477 12322.6295 1.4507 0.2149
Residuals 83 705040.6913 8494.4662


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 19.778 25.733   9 8.5777 1.3011 -0.87
A/J m 134.3 289.6   7 109.5 2.1565 2.0, 788.0 2.18
C57BL/6J f 36.333 31.827   12 9.1877 0.876 0.04
C57BL/6J m 19.583 17.239   12 4.9764 0.8803 3.0, 57.0 -0.5
CAST/EiJ f 30.0 0.0   1   0.0 0.0 30.0, 30.0 -0.31
CAST/EiJ m 34.0 24.042   2   17.0 0.7071 17.0, 51.0 -0.16
NOD/ShiLtJ f 72.9 128.0   10 40.477 1.7558 2.07
NOD/ShiLtJ m 24.833 18.862   6 7.7003 0.7595 -0.38
NZO/HlLtJ f 20.9 19.273   10 6.0945 0.9221 2.0, 54.0 -0.81
NZO/HlLtJ m 20.667 15.091   9 5.0305 0.7302 3.0, 47.0 -0.48
PWK/PhJ f 40.333 20.106   6 8.2084 0.4985 8.0, 71.0 0.27
PWK/PhJ m 46.143 63.33   7 23.938 1.3726 9.0, 186.0 0.12
WSB/EiJ f 28.5 34.648   2   24.5 1.2157 4.0, 53.0 -0.39
WSB/EiJ m 7.8 10.918   5 4.8826 1.3997 1.0, 27.0 -0.78


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 19.7777777778 30.7218094083 80.8822210651 -41.3266655095
A/J m 134.2857142857 34.8352575087 203.5716404025 64.9997881689
C57BL/6J f 36.3333333333 26.6058673978 89.2513335042 -16.5846668376
C57BL/6J m 19.5833333333 26.6058673978 72.5013335042 -33.3346668376
NOD/ShiLtJ f 72.9 29.1452674715 130.8687647833 14.9312352167
NOD/ShiLtJ m 24.8333333333 37.6263785127 99.6706868687 -50.004020202
NZO/HlLtJ f 20.9 29.1452674715 78.8687647833 -37.0687647833
NZO/HlLtJ m 20.6666666667 30.7218094083 81.771109954 -40.4377766206
PWK/PhJ f 40.3333333333 37.6263785127 115.1706868687 -34.504020202
PWK/PhJ m 46.1428571429 34.8352575087 115.4287832597 -23.143068974
WSB/EiJ f 28.5 65.1707992888 158.1220986273 -101.1220986273
WSB/EiJ m 7.8 41.2176325372 89.7802133506 -74.1802133506


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 77.0317460317 23.2235050058 123.222363443 30.8411286205
C57BL/6J both 27.9583333333 18.8131892563 65.377010101 -9.4603434344
NOD/ShiLtJ both 48.8666666667 23.7970112407 96.1979649129 1.5353684205
NZO/HlLtJ both 20.7833333333 21.1735459318 62.8966645954 -21.3299979287
PWK/PhJ both 43.2380952381 25.6380553361 94.2311561436 -7.7549656674
WSB/EiJ both 18.15 38.5555648121 94.8354677132 -58.5354677132




  GWAS USING LINEAR MIXED MODELS