Project measure / variable:   CSNA03   extinction_active_in_s5

ID, description, units MPD:110202   extinction_active_in_s5   extinction, active lever presses (intravenous self administration), founders   [n]  session 5  
cocaine study
Data set, strains CSNA03   inbred w/CC8   7 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, active lever presses (intravenous self administration), founders session 5



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means88.14   n 45.922   n
Median of the strain means72.0   n 29.5   n
SD of the strain means± 75.34 ± 30.802
Coefficient of variation (CV)0.8549 0.6708
Min–max range of strain means22.4   –   240.4   n 14.857   –   95.2   n
Mean sample size per strain6.7   mice 6.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 64677.5117 64677.5117 3.5186 0.0644
strain 5 216005.9555 43201.1911 2.3503 0.0483
sex:strain 5 148639.9659 29727.9932 1.6173 0.1651
Residuals 79 1452139.468 18381.5123


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 24.429 26.476   7 10.007 1.0838 -0.85
A/J m 14.857 26.175   7 9.8933 1.7618 -1.01
C57BL/6J f 240.4 339.3   11 102.3 1.4116 8.0, 1070.0 2.02
C57BL/6J m 48.455 37.901   11 11.428 0.7822 12.0, 139.0 0.08
CAST/EiJ f 72.0 0.0   1   0.0 0.0 72.0, 72.0 -0.21
CAST/EiJ m 29.5 12.021   2   8.5 0.4075 21.0, 38.0 -0.53
NOD/ShiLtJ f 73.8 113.7   10 35.95 1.5404 2.0, 326.0 -0.19
NOD/ShiLtJ m 95.2 91.41   5 40.878 0.9602 19.0, 246.0 1.6
NZO/HlLtJ f 22.4 16.05   10 5.0754 0.7165 -0.87
NZO/HlLtJ m 26.9 11.874   10 3.7548 0.4414 6.0, 39.0 -0.62
PWK/PhJ f 123.6 141.5   5 63.3 1.1451 33.0, 372.0 0.47
PWK/PhJ m 81.14 80.13   7 30.286 0.9875 1.0, 237.0 1.14
WSB/EiJ f 60.33 52.0   3 30.024 0.8619 13.0, 116.0 -0.37
WSB/EiJ m 25.4 14.993   5 6.7052 0.5903 10.0, 49.0 -0.67


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 24.4285714286 51.2438320368 126.4268676793 -77.5697248221
A/J m 14.8571428571 51.2438320368 116.8554391078 -87.1411533935
C57BL/6J f 240.3636363636 40.8784364724 321.730128834 158.9971438932
C57BL/6J m 48.4545454545 40.8784364724 129.821037925 -32.9119470159
NOD/ShiLtJ f 73.8 42.8736658716 159.1378972475 -11.5378972475
NOD/ShiLtJ m 95.2 60.6325197443 215.8860116719 -25.4860116719
NZO/HlLtJ f 22.4 42.8736658716 107.7378972475 -62.9378972475
NZO/HlLtJ m 26.9 42.8736658716 112.2378972475 -58.4378972475
PWK/PhJ f 123.6 60.6325197443 244.2860116719 2.9139883281
PWK/PhJ m 81.1428571429 51.2438320368 183.1411533935 -20.8554391078
WSB/EiJ f 60.3333333333 78.2762464028 216.1383044418 -95.4716377751
WSB/EiJ m 25.4 60.6325197443 146.0860116719 -95.2860116719


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 19.6428571429 36.2348611272 91.7665440912 -52.4808298055
C57BL/6J both 144.4090909091 28.905419634 201.9438894963 86.8742923219
NOD/ShiLtJ both 84.5 37.1296837982 158.4047869219 10.5952130781
NZO/HlLtJ both 24.65 30.3162598722 84.9930058359 -35.6930058359
PWK/PhJ both 102.3714285714 39.6933016149 181.3789691155 23.3638880273
WSB/EiJ both 42.8666666667 49.5062450643 141.4063825625 -55.6730492292




  GWAS USING LINEAR MIXED MODELS