Project measure / variable:   CSNA03   extinction_active_in_s3

ID, description, units MPD:110200   extinction_active_in_s3   extinction, active lever presses (intravenous self administration), founders   [n]  session 3  
cocaine study
Data set, strains CSNA03   inbred w/CC8   7 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

  STRAIN COMPARISON PLOT
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CSNA03 - extinction, active lever presses (intravenous self administration), founders session 3



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means88.98   n 46.573   n
Median of the strain means94.0   n 42.462   n
SD of the strain means± 74.27 ± 22.316
Coefficient of variation (CV)0.8347 0.4792
Min–max range of strain means15.5   –   226.5   n 17.286   –   80.43   n
Mean sample size per strain7.0   mice 7.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 82602.6667 82602.6667 5.3496 0.0232
strain 5 169971.0734 33994.2147 2.2016 0.0616
sex:strain 5 133287.1136 26657.4227 1.7264 0.1374
Residuals 84 1297028.9797 15440.8212


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 17.75 23.975   8 8.4763 1.3507 -0.96
A/J m 17.286 19.19   7 7.253 1.1101 -1.31
C57BL/6J f 226.5 281.2   11 84.79 1.2413 19.0, 1005.0 1.85
C57BL/6J m 42.462 28.445   13 7.8891 0.6699 5.0, 104.0 -0.18
CAST/EiJ f 94.0 0.0   1   0.0 0.0 94.0, 94.0 0.07
CAST/EiJ m 44.0 2.8284   2   2.0 0.0643 42.0, 46.0 -0.12
NOD/ShiLtJ f 116.4 180.7   11 54.47 1.5526 3.0, 483.0 0.37
NOD/ShiLtJ m 72.33 88.54   6 36.146 1.224 4.0, 193.0 1.15
NZO/HlLtJ f 40.2 56.2   10 17.772 1.398 -0.66
NZO/HlLtJ m 37.7 41.82   10 13.225 1.1093 7.0, 143.0 -0.4
PWK/PhJ f 112.5 112.6   6 45.967 1.0009 29.0, 324.0 0.32
PWK/PhJ m 80.43 51.38   7 19.42 0.6388 7.0, 138.0 1.52
WSB/EiJ f 15.5 0.70711   2   0.5 0.0456 15.0, 16.0 -0.99
WSB/EiJ m 31.8 18.377   5 8.2183 0.5779 11.0, 54.0 -0.66


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 17.75 43.9329335276 105.1154563117 -69.6154563117
A/J m 17.2857142857 46.9662815018 110.6833157021 -76.1118871307
C57BL/6J f 226.5454545455 37.4661315988 301.050966027 152.0399430639
C57BL/6J m 42.4615384615 34.4638285149 110.9966410072 -26.0735640842
NOD/ShiLtJ f 116.3636363636 37.4661315988 190.8691478452 41.8581248821
NOD/ShiLtJ m 72.3333333333 50.7293819969 173.2142727722 -28.5476061055
NZO/HlLtJ f 40.2 39.2948103275 118.3420396793 -37.9420396793
NZO/HlLtJ m 37.7 39.2948103275 115.8420396793 -40.4420396793
PWK/PhJ f 112.5 50.7293819969 213.3809394388 11.6190605612
PWK/PhJ m 80.4285714286 46.9662815018 173.826172845 -12.9690299878
WSB/EiJ f 15.5 87.8658670553 190.2309126233 -159.2309126233
WSB/EiJ m 31.8 55.571253696 142.3095323059 -78.7095323059


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 17.5178571429 32.1556147758 81.4628235337 -46.4271092479
C57BL/6J both 134.5034965035 25.4532242205 185.1200242441 83.8869687629
NOD/ShiLtJ both 94.3484848485 31.5324484253 157.0542166104 31.6427530866
NZO/HlLtJ both 38.95 27.785626848 94.204766153 -16.304766153
PWK/PhJ both 96.4642857143 34.5662472504 165.2030591475 27.7255122811
WSB/EiJ both 23.65 51.982147971 127.0222019653 -79.7222019653




  GWAS USING LINEAR MIXED MODELS