Phenotype measure

ID, description, units MPD:43937   QT_dispersion   difference between smallest and largest QT interval   [ms]
Data set, strains CGDpheno3   CC diallel w/par   42 strains     sex: both     age: 12wks
Procedure ECG
Ontology mappings

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  STRAIN COMPARISON PLOT
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CGDpheno3 - difference between smallest and largest QT interval



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested42 strains39 strains
Mean of the strain means20.8   ms 19.2   ms
Median of the strain means19.7   ms 18.8   ms
SD of the strain means± 5.09 ± 5.16
Coefficient of variation (CV)0.245 0.269
Min–max range of strain means12.6   –   39.2   ms 6.75   –   31.1   ms
Mean sample size per strain4.8   mice 4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 347.8424 347.8424 6.1322 0.0138
strain 38 7074.3888 186.1681 3.282 < 0.0001
sex:strain 38 2161.3826 56.8785 1.0027 0.4703
Residuals 306 17357.4168 56.7236


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129SAF1 f 23.7 6.7   5 2.99 0.282 14.5, 30.5 0.57
129SAF1 m 18.0 4.37   5 1.96 0.243 12.0, 23.0 -0.22
129SB6F1 f 13.4 5.07   5 2.27 0.378 8.5, 19.0 -1.45
129SCASTF1 f 19.1 5.99   5 2.68 0.314 8.5, 23.0 -0.33
129SCASTF1 m 11.8 4.88   5 2.18 0.414 6.5, 19.5 -1.43
129SNZOF1 f 26.6 6.55   7 2.48 0.246 18.5, 38.5 1.14
129SNZOF1 m 20.4 8.09   13 2.24 0.397 2.0, 36.5 0.24
129SPWKF1 f 26.5 7.0   3 4.04 0.264 19.5, 33.5 1.12
129SPWKF1 m 21.8 0.758   5 0.339 0.0348 20.5, 22.5 0.51
129SWSBF1 f 19.2 4.6   2   3.25 0.239 16.0, 22.5 -0.32
129SWSBF1 m 6.75 8.13   2   5.75 1.2 1.0, 12.5 -2.4
A129SF1 f 39.2 15.8   5 7.04 0.402 21.5, 56.0 3.61
A129SF1 m 22.7 8.87   5 3.97 0.391 15.0, 32.5 0.69
AB6F1 f 23.7 6.13   5 2.74 0.259 20.0, 34.5 0.57
AB6F1 m 23.2 1.89   5 0.846 0.0815 21.0, 25.5 0.78
ACASTF1 f 14.0 13.6   4 6.79 0.97 4.0, 33.5 -1.34
A/J f 25.0 6.03   5 2.7 0.241 19.0, 31.5 0.82
A/J m 30.2 15.5   5 6.94 0.514 19.5, 56.0 2.14
ANODF1 f 23.4 2.95   5 1.32 0.126 20.5, 28.0 0.51
ANODF1 m 23.2 2.39   5 1.07 0.103 20.5, 27.0 0.78
ANZOF1 f 30.6 15.7   5 7.02 0.513 22.0, 58.5 1.92
ANZOF1 m 18.8 3.13   5 1.4 0.167 16.0, 23.5 -0.07
B6129SF1/J f 21.8 5.96   5 2.67 0.274 16.0, 29.0 0.2
B6129SF1/J m 17.9 3.36   5 1.5 0.188 13.5, 21.5 -0.24
B6AF1/J f 23.5 6.73   5 3.01 0.286 17.0, 33.0 0.53
B6AF1/J m 31.1 23.0   5 10.3 0.74 16.5, 71.5 2.32
B6CASTF1 f 19.7 5.11   5 2.28 0.259 14.0, 26.0 -0.22
B6CASTF1 m 19.5 3.98   5 1.78 0.204 14.5, 24.5 0.07
B6NODF1 f 18.7 4.63   5 2.07 0.248 12.0, 23.5 -0.41
B6NODF1 m 19.0 2.69   5 1.2 0.142 16.5, 22.5 -0.03
B6NZOF1 f 28.4 14.8   5 6.61 0.52 17.0, 52.0 1.49
B6NZOF1 m 18.4 4.42   5 1.98 0.24 14.0, 24.5 -0.15
B6PWKF1 f 24.3 5.46   5 2.44 0.225 18.0, 31.0 0.69
B6PWKF1 m 27.5 14.6   5 6.54 0.532 19.0, 53.5 1.62
B6WSBF1 f 22.5 5.93   5 2.65 0.263 16.0, 31.5 0.33
B6WSBF1 m 21.9 3.25   5 1.45 0.148 17.0, 25.5 0.53
C57BL/6J f 19.7 9.98   5 4.47 0.507 2.5, 28.5 -0.22
C57BL/6J m 19.6 3.6   5 1.61 0.183 13.5, 22.5 0.09
CAST129SF1 f 12.6 9.26   5 4.14 0.735 3.5, 25.5 -1.61
CAST129SF1 m 12.8 8.74   5 3.91 0.683 2.0, 23.0 -1.23
CASTAF1 f 20.8 12.0   3 6.93 0.576 10.5, 34.0 0.0
CASTAF1 m 20.6 9.11   5 4.07 0.442 12.5, 35.5 0.28
CASTNZOF1 f 19.8 5.99   5 2.68 0.302 12.0, 27.0 -0.2
CASTNZOF1 m 16.8 3.11   5 1.39 0.185 12.5, 20.5 -0.46
NOD129SF1 f 17.7 7.47   5 3.34 0.422 11.0, 26.0 -0.61
NOD129SF1 m 15.7 2.93   5 1.31 0.187 13.5, 20.0 -0.67
NODAF1 f 25.4 6.51   5 2.91 0.256 19.5, 36.0 0.9
NODAF1 m 22.7 4.44   5 1.98 0.196 18.0, 29.0 0.69
NODB6F1 f 18.0 5.53   5 2.47 0.307 10.0, 23.0 -0.55
NODB6F1 m 13.5 7.56   5 3.38 0.56 1.0, 21.5 -1.1
NODCASTF1 f 12.8 1.64   5 0.735 0.128 11.0, 15.0 -1.57
NODCASTF1 m 9.3 3.68   5 1.65 0.396 5.5, 13.5 -1.91
NODNZOF1 f 16.3 4.37   5 1.95 0.268 12.0, 21.5 -0.88
NODNZOF1 m 18.6 4.46   5 2.0 0.24 11.0, 22.0 -0.11
NODPWKF1 f 17.2 5.54   7 2.09 0.322 10.5, 24.5 -0.71
NODPWKF1 m 18.5 4.32   5 1.93 0.233 13.5, 25.0 -0.13
NOD/ShiLtJ f 18.0 3.91   5 1.75 0.217 12.5, 22.0 -0.55
NOD/ShiLtJ m 16.1 3.58   5 1.6 0.222 11.5, 21.0 -0.59
NZO129SF1 f 18.2 2.22   5 0.995 0.122 15.5, 21.5 -0.51
NZO129SF1 m 17.1 8.15   5 3.64 0.477 3.0, 23.5 -0.4
NZOAF1 f 20.9 1.44   4 0.718 0.0688 19.0, 22.5 0.02
NZOAF1 m 20.4 6.16   5 2.75 0.302 12.5, 28.0 0.24
NZOB6F1 f 18.2 4.15   5 1.85 0.228 12.0, 22.0 -0.51
NZOB6F1 m 22.3 1.3   5 0.583 0.0585 21.0, 24.5 0.61
NZO/HlLtJ f 15.1 4.56   5 2.04 0.302 10.5, 22.0 -1.12
NZO/HlLtJ m 13.3 6.32   5 2.83 0.475 5.0, 20.0 -1.14
NZONODF1 f 18.2 5.73   5 2.56 0.315 12.0, 25.0 -0.51
NZONODF1 m 19.0 6.75   5 3.02 0.356 9.0, 24.5 -0.03
NZOWSBF1 f 21.7 10.6   5 4.73 0.487 11.0, 39.0 0.18
NZOWSBF1 m 16.8 2.39   5 1.07 0.142 13.0, 19.5 -0.46
PWK129SF1 f 18.6 4.55   5 2.03 0.244 15.0, 26.5 -0.43
PWK129SF1 m 24.2 4.54   3 2.62 0.188 19.0, 27.5 0.98
PWKAF1 f 26.2 15.8   5 7.08 0.604 10.5, 47.5 1.06
PWKAF1 m 28.5 15.6   5 6.98 0.548 17.5, 56.0 1.81
PWKB6F1 f 19.2 2.14   5 0.957 0.111 17.0, 22.5 -0.32
PWKB6F1 m 16.0 2.03   5 0.908 0.127 14.0, 18.5 -0.61
PWKNZOF1 f 21.1 0.822   5 0.367 0.0389 20.0, 22.0 0.06
PWKNZOF1 m 16.3 3.62   3 2.09 0.221 14.0, 20.5 -0.55
WSBAF1 f 18.0 0.0   1   0.0 0.0 18.0, 18.0 -0.55
WSBNZOF1 f 16.8 1.89   3 1.09 0.112 15.5, 19.0 -0.79
WSBNZOF1 m 16.8 2.84   4 1.42 0.17 12.5, 18.5 -0.46


  LEAST SQUARES MEANS (ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 f 23.7 3.3682 30.3277 17.0723
129SAF1 m 18.0 3.3682 24.6277 11.3723
129SCASTF1 f 19.1 3.3682 25.7277 12.4723
129SCASTF1 m 11.8 3.3682 18.4277 5.1723
129SNZOF1 f 26.6429 2.8466 32.2443 21.0414
129SNZOF1 m 20.3846 2.0889 24.495 16.2743
129SPWKF1 f 26.5 4.3483 35.0564 17.9436
129SPWKF1 m 21.8 3.3682 28.4277 15.1723
129SWSBF1 f 19.25 5.3256 29.7294 8.7706
129SWSBF1 m 6.75 5.3256 17.2294 0.0
A129SF1 f 39.2 3.3682 45.8277 32.5723
A129SF1 m 22.7 3.3682 29.3277 16.0723
AB6F1 f 23.7 3.3682 30.3277 17.0723
AB6F1 m 23.2 3.3682 29.8277 16.5723
A/J f 25.0 3.3682 31.6277 18.3723
A/J m 30.2 3.3682 36.8277 23.5723
ANODF1 f 23.4 3.3682 30.0277 16.7723
ANODF1 m 23.2 3.3682 29.8277 16.5723
ANZOF1 f 30.6 3.3682 37.2277 23.9723
ANZOF1 m 18.8 3.3682 25.4277 12.1723
B6129SF1/J f 21.8 3.3682 28.4277 15.1723
B6129SF1/J m 17.9 3.3682 24.5277 11.2723
B6AF1/J f 23.5 3.3682 30.1277 16.8723
B6AF1/J m 31.1 3.3682 37.7277 24.4723
B6CASTF1 f 19.7 3.3682 26.3277 13.0723
B6CASTF1 m 19.5 3.3682 26.1277 12.8723
B6NODF1 f 18.7 3.3682 25.3277 12.0723
B6NODF1 m 19.0 3.3682 25.6277 12.3723
B6NZOF1 f 28.4 3.3682 35.0277 21.7723
B6NZOF1 m 18.4 3.3682 25.0277 11.7723
B6PWKF1 f 24.3 3.3682 30.9277 17.6723
B6PWKF1 m 27.5 3.3682 34.1277 20.8723
B6WSBF1 f 22.5 3.3682 29.1277 15.8723
B6WSBF1 m 21.9 3.3682 28.5277 15.2723
C57BL/6J f 19.7 3.3682 26.3277 13.0723
C57BL/6J m 19.6 3.3682 26.2277 12.9723
CAST129SF1 f 12.6 3.3682 19.2277 5.9723
CAST129SF1 m 12.8 3.3682 19.4277 6.1723
CASTAF1 f 20.8333 4.3483 29.3897 12.2769
CASTAF1 m 20.6 3.3682 27.2277 13.9723
CASTNZOF1 f 19.8 3.3682 26.4277 13.1723
CASTNZOF1 m 16.8 3.3682 23.4277 10.1723
NOD129SF1 f 17.7 3.3682 24.3277 11.0723
NOD129SF1 m 15.7 3.3682 22.3277 9.0723
NODAF1 f 25.4 3.3682 32.0277 18.7723
NODAF1 m 22.7 3.3682 29.3277 16.0723
NODB6F1 f 18.0 3.3682 24.6277 11.3723
NODB6F1 m 13.5 3.3682 20.1277 6.8723
NODCASTF1 f 12.8 3.3682 19.4277 6.1723
NODCASTF1 m 9.3 3.3682 15.9277 2.6723
NODNZOF1 f 16.3 3.3682 22.9277 9.6723
NODNZOF1 m 18.6 3.3682 25.2277 11.9723
NODPWKF1 f 17.2143 2.8466 22.8158 11.6128
NODPWKF1 m 18.5 3.3682 25.1277 11.8723
NOD/ShiLtJ f 18.0 3.3682 24.6277 11.3723
NOD/ShiLtJ m 16.1 3.3682 22.7277 9.4723
NZO129SF1 f 18.2 3.3682 24.8277 11.5723
NZO129SF1 m 17.1 3.3682 23.7277 10.4723
NZOAF1 f 20.875 3.7658 28.285 13.465
NZOAF1 m 20.4 3.3682 27.0277 13.7723
NZOB6F1 f 18.2 3.3682 24.8277 11.5723
NZOB6F1 m 22.3 3.3682 28.9277 15.6723
NZO/HlLtJ f 15.1 3.3682 21.7277 8.4723
NZO/HlLtJ m 13.3 3.3682 19.9277 6.6723
NZONODF1 f 18.2 3.3682 24.8277 11.5723
NZONODF1 m 19.0 3.3682 25.6277 12.3723
NZOWSBF1 f 21.7 3.3682 28.3277 15.0723
NZOWSBF1 m 16.8 3.3682 23.4277 10.1723
PWK129SF1 f 18.6 3.3682 25.2277 11.9723
PWK129SF1 m 24.1667 4.3483 32.7231 15.6103
PWKAF1 f 26.2 3.3682 32.8277 19.5723
PWKAF1 m 28.5 3.3682 35.1277 21.8723
PWKB6F1 f 19.2 3.3682 25.8277 12.5723
PWKB6F1 m 16.0 3.3682 22.6277 9.3723
PWKNZOF1 f 21.1 3.3682 27.7277 14.4723
PWKNZOF1 m 16.3333 4.3483 24.8897 7.7769
WSBNZOF1 f 16.8333 4.3483 25.3897 8.2769
WSBNZOF1 m 16.75 3.7658 24.16 9.34


  LEAST SQUARES MEANS (ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 both 20.85 2.3817 25.5365 16.1635
129SCASTF1 both 15.45 2.3817 20.1365 10.7635
129SNZOF1 both 23.5137 1.7654 26.9876 20.0399
129SPWKF1 both 24.15 2.7501 29.5615 18.7385
129SWSBF1 both 13.0 3.7658 20.41 5.59
A129SF1 both 30.95 2.3817 35.6365 26.2635
AB6F1 both 23.45 2.3817 28.1365 18.7635
A/J both 27.6 2.3817 32.2865 22.9135
ANODF1 both 23.3 2.3817 27.9865 18.6135
ANZOF1 both 24.7 2.3817 29.3865 20.0135
B6129SF1/J both 19.85 2.3817 24.5365 15.1635
B6AF1/J both 27.3 2.3817 31.9865 22.6135
B6CASTF1 both 19.6 2.3817 24.2865 14.9135
B6NODF1 both 18.85 2.3817 23.5365 14.1635
B6NZOF1 both 23.4 2.3817 28.0865 18.7135
B6PWKF1 both 25.9 2.3817 30.5865 21.2135
B6WSBF1 both 22.2 2.3817 26.8865 17.5135
C57BL/6J both 19.65 2.3817 24.3365 14.9635
CAST129SF1 both 12.7 2.3817 17.3865 8.0135
CASTAF1 both 20.7167 2.7501 26.1282 15.3051
CASTNZOF1 both 18.3 2.3817 22.9865 13.6135
NOD129SF1 both 16.7 2.3817 21.3865 12.0135
NODAF1 both 24.05 2.3817 28.7365 19.3635
NODB6F1 both 15.75 2.3817 20.4365 11.0635
NODCASTF1 both 11.05 2.3817 15.7365 6.3635
NODNZOF1 both 17.45 2.3817 22.1365 12.7635
NODPWKF1 both 17.8571 2.205 22.196 13.5183
NOD/ShiLtJ both 17.05 2.3817 21.7365 12.3635
NZO129SF1 both 17.65 2.3817 22.3365 12.9635
NZOAF1 both 20.6375 2.5261 25.6083 15.6667
NZOB6F1 both 20.25 2.3817 24.9365 15.5635
NZO/HlLtJ both 14.2 2.3817 18.8865 9.5135
NZONODF1 both 18.6 2.3817 23.2865 13.9135
NZOWSBF1 both 19.25 2.3817 23.9365 14.5635
PWK129SF1 both 21.3833 2.7501 26.7949 15.9718
PWKAF1 both 27.35 2.3817 32.0365 22.6635
PWKB6F1 both 17.6 2.3817 22.2865 12.9135
PWKNZOF1 both 18.7167 2.7501 24.1282 13.3051
WSBNZOF1 both 16.7917 2.8761 22.4512 11.1321