Phenotype measures set

ID, description, units MPD:9906   total cholesterol   [mg/dL]
high-fat diet study
Measures • baseline    • after 17wks on diet    • Δchange
Data set, strains Paigen2   inbred w/CC7   41 strains     sex: both     age: 7-9wks
Procedure lipid profile
Comparisonrepeated measures, baseline then treated, same cohort
Ontology mappings



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Paigen2 - total cholesterol

Female

Male



  RM-ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   sex 1 35076.027 35076.027 7.4344 0.0066
between   strain 33 11815340.9412 358040.6346 75.8867 < 0.0001
between   sex:strain 33 1234319.4178 37403.6187 7.9277 < 0.0001
between   Residuals 505 2382636.6104 4718.0923
within   group 1 8634447.3613 8634447.3613 1852.993 < 0.0001
within   group:sex 1 5839.2839 5839.2839 1.2531 0.2635
within   group:strain 33 11601059.4881 351547.2572 75.4437 < 0.0001
within   group:sex:strain 33 1217753.1505 36901.6106 7.9193 < 0.0001
within   Residuals 505 2353163.7163 4659.7301

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDDrug or
challenge
Description and varname PanelNo.
strains
SexAge
Paigen2 9906 lipid profile high-fat diet total cholesterol   [mg/dL]   baseline   CHOL inbred w/CC7 41 both 7-9wks
Paigen2 9909 lipid profile high-fat diet total cholesterol   [mg/dL]   after 17wks on diet   CHOL_fat17 inbred w/CC7 41 both 7-9wks
Paigen2 9912 lipid profile high-fat diet total cholesterol   [mg/dL]   fold change   CHOL_chg inbred w/CC7 41 both 7-9wks (not included in the analysis / display)